Detailed information NTG0687177

Bioinformatically predicted

Overview

• Name: braS
• Type: Regulator
• Locus tag: M3J23_RS12755
• Genome accession: NZ_CP097113
• Coordinates: 2585305..2586192 (-)
• Length: 295 a.a.
• NCBI ID: WP_000143419.1
• Uniprot ID: A0A266CLT2
• Organism: Staphylococcus aureus strain JP1250
• Function: promote expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 2580305..2591192

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
M3J23_RS12725 (M3J23_12715)	-	2580324..2580416 (+)	93	WP_010956583.1	hypothetical protein	-
M3J23_RS12730 (M3J23_12720)	-	2580524..2581021 (-)	498	WP_001065268.1	glutathione peroxidase	-
M3J23_RS12735 (M3J23_12725)	-	2581031..2581291 (-)	261	WP_001789910.1	hypothetical protein	-
M3J23_RS12740 (M3J23_12730)	-	2581673..2581786 (-)	114	WP_011447078.1	hypothetical protein	-
M3J23_RS12745 (M3J23_12735)	-	2582445..2584445 (-)	2001	WP_000776751.1	ABC transporter permease	-
M3J23_RS12750 (M3J23_12740)	-	2584442..2585197 (-)	756	WP_000923760.1	ABC transporter ATP-binding protein	-
M3J23_RS12755 (M3J23_12745)	braS	2585305..2586192 (-)	888	WP_000143419.1	nisin susceptibility-associated two-component system sensor histidine kinase NsaS	Regulator
M3J23_RS12760 (M3J23_12750)	braR	2586203..2586868 (-)	666	WP_000697886.1	nisin susceptibility-associated two-component system response regulator NsaR	Regulator
M3J23_RS12765 (M3J23_12755)	-	2586894..2587094 (-)	201	WP_000604728.1	hypothetical protein	-
M3J23_RS12770 (M3J23_12760)	-	2587292..2588716 (+)	1425	WP_000953744.1	alkaline phosphatase	-
M3J23_RS13240	-	2588776..2588877 (-)	102	WP_000731972.1	SE2200 family small protein	-
M3J23_RS12780 (M3J23_12770)	-	2588999..2589454 (-)	456	WP_000106185.1	MarR family winged helix-turn-helix transcriptional regulator	-
M3J23_RS12785 (M3J23_12775)	-	2589699..2590460 (-)	762	WP_000323455.1	alpha/beta hydrolase family protein	-

Sequence

Protein

• Length: 295 a.a.
• Molecular weight: 34019.28 Da
• Isoelectric Point: 6.0874

>NTDB_id=687177 M3J23_RS12755 WP_000143419.1 2585305..2586192(-) (braS) [Staphylococcus aureus strain JP1250]
MTFLKSITQEIAIVIVIFALFGLMFYLYHLPLEAYLLALGVILLLLLIFIGIKYLSFVKTISQQQQIENLENALYQLKNE
QIEYKNDVESYFLTWVHQMKTPITAAQLLLERDEPNVVNRVRQEVIQIDNYTSLALSYLKLLNETSDISVTKISINNIIR
PIIMKYSIQFIDQKTKIHYEPCHHEVLTDVRWTSLMIEQLINNALKYARGKDIWIEFDEQSNQLHVKDNGIGISEADLPK
IFDKGYSGYNGQRQSNSSGIGLFIVKQISTHTNHPVSVVSKQNEGTTFTIQFPDE

Nucleotide

• Length: 888 bp

>NTDB_id=687177 M3J23_RS12755 WP_000143419.1 2585305..2586192(-) (braS) [Staphylococcus aureus strain JP1250]
ATGACCTTTCTTAAAAGTATTACTCAGGAAATAGCAATAGTCATAGTTATTTTTGCTTTGTTTGGCTTAATGTTTTACCT
GTATCATTTGCCATTAGAAGCATATTTACTAGCACTTGGCGTTATTTTATTATTATTACTCATATTCATAGGTATTAAAT
ATTTAAGTTTTGTAAAAACTATAAGCCAACAACAACAAATTGAAAACTTAGAAAATGCGTTGTATCAGCTTAAAAATGAA
CAAATTGAATATAAAAATGATGTAGAGAGCTACTTTTTAACATGGGTACATCAAATGAAAACACCCATTACTGCAGCACA
ACTGTTACTTGAAAGAGATGAGCCTAATGTTGTTAATCGTGTTCGTCAAGAGGTTATTCAAATTGATAACTATACAAGTT
TAGCACTTAGTTATTTAAAGTTATTAAATGAAACTTCTGATATTTCTGTCACTAAAATTTCGATTAATAATATCATTCGC
CCAATTATTATGAAATATTCAATACAGTTTATTGATCAAAAAACAAAAATCCATTATGAACCTTGTCATCACGAAGTATT
AACTGACGTTAGATGGACCTCTTTAATGATAGAACAATTAATAAATAATGCACTTAAGTATGCGAGAGGTAAAGATATAT
GGATTGAATTTGATGAGCAATCCAATCAATTACACGTAAAAGATAATGGTATCGGTATTAGTGAAGCGGACTTGCCTAAA
ATATTTGATAAGGGCTATTCAGGTTATAATGGCCAGCGCCAAAGTAACTCAAGTGGGATTGGTTTATTTATCGTAAAACA
AATTTCAACACACACAAACCATCCTGTTTCAGTCGTATCTAAACAAAATGAGGGTACAACATTTACGATTCAATTTCCAG
ATGAATAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (191-294)

3D structure

• AlphaFold DB: A0A266CLT2

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
braS	Staphylococcus aureus N315	99.661	100	0.997