Detailed information    

insolico Bioinformatically predicted

Overview

Name   agrA   Type   Regulator
Locus tag   JP49775_RS10110 Genome accession   NZ_AP017922
Coordinates   2016657..2017373 (+) Length   238 a.a.
NCBI ID   WP_000688492.1    Uniprot ID   A0A7U7IEW1
Organism   Staphylococcus aureus strain JP02758     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 2011657..2022373
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  JP49775_RS10080 (JP02758_1872) - 2011871..2012497 (+) 627 WP_000522384.1 nitroreductase family protein -
  JP49775_RS10085 (JP02758_1873) - 2012858..2013643 (+) 786 WP_029550164.1 carbon-nitrogen family hydrolase -
  JP49775_RS14180 hld 2014245..2014325 (-) 81 WP_000046022.1 delta-hemolysin -
  JP49775_RS10095 (JP02758_1875) agrB 2014615..2015184 (+) 570 WP_001105708.1 accessory gene regulator AgrB -
  JP49775_RS10100 (JP02758_1876) agrD 2015181..2015321 (+) 141 WP_001093929.1 cyclic lactone autoinducer peptide AgrD -
  JP49775_RS10105 (JP02758_1877) agrC 2015346..2016638 (+) 1293 WP_001825886.1 quorum-sensing sensor histidine kinase AgrC -
  JP49775_RS10110 (JP02758_1878) agrA 2016657..2017373 (+) 717 WP_000688492.1 quorum-sensing response regulator AgrA Regulator
  JP49775_RS10115 (JP02758_1879) - 2017745..2018704 (-) 960 WP_029550165.1 carbohydrate kinase family protein -
  JP49775_RS10120 (JP02758_1880) - 2018701..2020185 (-) 1485 WP_029550166.1 sucrose-6-phosphate hydrolase -
  JP49775_RS10125 (JP02758_1881) - 2020334..2021284 (-) 951 WP_000790325.1 LacI family DNA-binding transcriptional regulator -

Sequence

Protein


Download         Length: 238 a.a.        Molecular weight: 27905.90 Da        Isoelectric Point: 6.0927

>NTDB_id=68509 JP49775_RS10110 WP_000688492.1 2016657..2017373(+) (agrA) [Staphylococcus aureus strain JP02758]
MKIFICEDDPKQRENMVTIIKNYIMIEEKPMEIALATDNPYEVLEQAKNMNDIGCYFLDIQLSTDINGIKLGSEIRKHDP
VGNIIFVTSHSELTYLTFVYKVAAMDFIFKDDPAELRTRIIDCLETAHTRLQLLSKDNSVETIELKRGSNSVYVQYDDIM
FFESSTKSHRLIAHLDNRQIEFYGNLKELSQLDDRFFRCHNSFVVNRHNIESIDSKERIVYFKNKEHCYASVRNVKKI

Nucleotide


Download         Length: 717 bp        

>NTDB_id=68509 JP49775_RS10110 WP_000688492.1 2016657..2017373(+) (agrA) [Staphylococcus aureus strain JP02758]
ATGAAAATTTTCATTTGCGAAGACGATCCAAAACAAAGAGAAAACATGGTTACCATTATTAAAAATTATATAATGATAGA
AGAAAAGCCTATGGAAATTGCCCTCGCAACTGATAATCCTTATGAGGTGCTTGAGCAAGCTAAAAATATGAATGACATAG
GCTGTTACTTTTTAGATATTCAACTTTCAACTGATATTAATGGTATCAAATTAGGCAGTGAAATTCGTAAGCATGACCCA
GTTGGTAACATTATTTTCGTTACGAGTCACAGTGAACTTACGTATTTAACATTTGTCTACAAAGTTGCAGCGATGGATTT
TATTTTTAAAGATGATCCAGCAGAATTAAGAACTCGAATTATAGATTGTTTAGAAACTGCACATACACGCTTACAATTAT
TATCAAAAGATAATAGCGTTGAAACGATTGAGTTAAAACGTGGCAGTAATTCAGTGTATGTTCAATATGATGATATTATG
TTTTTTGAATCATCAACAAAATCTCACAGACTCATTGCCCATTTAGATAACCGTCAAATTGAATTTTATGGTAATTTAAA
AGAACTGAGTCAATTAGATGATCGTTTCTTCAGATGTCATAATAGCTTTGTCGTCAATCGTCATAATATCGAATCTATTG
ATTCGAAAGAGCGTATTGTTTATTTTAAAAATAAAGAACACTGCTATGCATCGGTGAGAAACGTTAAAAAAATATAA

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(3-120)

LytTr DNA-binding domain (LytTR)

(151-237)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A7U7IEW1

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  agrA Staphylococcus aureus N315

100

100

1

Multiple sequence alignment