Detailed information    

insolico Bioinformatically predicted

Overview

Name   mecA   Type   Regulator
Locus tag   EFK13_RS06435 Genome accession   NZ_CP096889
Coordinates   1254655..1255311 (+) Length   218 a.a.
NCBI ID   WP_014113374.1    Uniprot ID   G4NWF3
Organism   Bacillus cabrialesii strain TE3     
Function   degradation of ComK (predicted from homology)   
Competence regulation

Genomic Context

Location: 1249655..1260311
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EFK13_RS06405 (EFK13_06405) oppF 1250105..1251022 (+) 918 WP_129506079.1 oligopeptide ABC transporter ATP-binding protein OppF -
  EFK13_RS06410 (EFK13_06410) - 1251131..1252348 (+) 1218 WP_129506169.1 MFS transporter -
  EFK13_RS06415 (EFK13_06415) - 1252522..1253100 (+) 579 WP_129506078.1 GNAT family N-acetyltransferase -
  EFK13_RS06420 (EFK13_06420) spx 1253281..1253676 (+) 396 WP_003224599.1 transcriptional regulator Spx -
  EFK13_RS06425 (EFK13_06425) - 1253718..1254377 (-) 660 WP_129506168.1 TerC family protein -
  EFK13_RS06430 (EFK13_06430) - 1254563..1254688 (+) 126 WP_119913679.1 hypothetical protein -
  EFK13_RS06435 (EFK13_06435) mecA 1254655..1255311 (+) 657 WP_014113374.1 adaptor protein MecA Regulator
  EFK13_RS06440 (EFK13_06440) coiA 1255469..1256620 (+) 1152 WP_129506077.1 competence protein CoiA family protein Machinery gene
  EFK13_RS06445 (EFK13_06445) pepF 1256850..1258679 (+) 1830 WP_167470872.1 oligoendopeptidase F -
  EFK13_RS06450 (EFK13_06450) - 1258718..1258885 (-) 168 WP_019713977.1 hypothetical protein -
  EFK13_RS06455 (EFK13_06455) spxH 1259199..1260098 (-) 900 WP_129506074.1 protease adaptor protein SpxH -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 25730.60 Da        Isoelectric Point: 4.1174

>NTDB_id=684863 EFK13_RS06435 WP_014113374.1 1254655..1255311(+) (mecA) [Bacillus cabrialesii strain TE3]
MEIERINEHTVKFYMSYGDIEDRGFDREEIWYNRERSEELFWEVMDEVHEEEEFAVEGPLWIQVQALDKGLEIIVTKAQL
SKDGQKLELPIPEDKKQEPASEDLDALLDDFQKEEQAVNQEEKEQKLQFVLRFGDFEDVISLSKLNVNGSKTTLYSFENR
YYLYVDFGNMTDEEVENQLSILLEYANESSISIHRLEEYGKLIISEHALETIKKHFAS

Nucleotide


Download         Length: 657 bp        

>NTDB_id=684863 EFK13_RS06435 WP_014113374.1 1254655..1255311(+) (mecA) [Bacillus cabrialesii strain TE3]
ATGGAAATTGAAAGAATTAACGAGCATACAGTAAAATTTTATATGTCTTACGGAGATATTGAAGATCGCGGTTTTGACAG
AGAAGAAATTTGGTATAACCGTGAGCGCAGTGAAGAACTTTTCTGGGAAGTCATGGATGAAGTTCATGAAGAAGAGGAAT
TTGCTGTGGAAGGCCCTCTTTGGATTCAAGTTCAGGCACTGGACAAAGGATTAGAAATCATCGTCACAAAAGCCCAGCTT
TCCAAAGACGGACAAAAGCTCGAACTGCCGATTCCTGAGGATAAAAAGCAAGAACCAGCATCTGAGGATCTTGACGCCTT
GCTGGATGATTTCCAGAAAGAAGAGCAAGCCGTCAATCAGGAAGAGAAGGAGCAAAAGCTTCAATTTGTCTTGCGGTTTG
GCGATTTTGAGGATGTTATTTCTCTATCTAAATTGAACGTTAACGGAAGCAAAACGACTTTATATTCGTTTGAGAACCGA
TATTATTTATATGTAGATTTTGGCAATATGACTGATGAAGAGGTTGAAAATCAGCTAAGCATCCTGTTGGAGTACGCAAA
TGAATCCTCAATCAGCATACACCGTCTTGAAGAATACGGCAAGCTGATTATTTCAGAGCATGCTCTAGAAACGATAAAAA
AACACTTTGCATCATAA

Domains

Predicted by InterproScan.

Negative regulator of genetic competence (MecA) (MecA)

(1-212)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB G4NWF3

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  mecA Bacillus subtilis subsp. subtilis str. 168

99.083

100

0.991