Detailed information NTG0068429

Bioinformatically predicted

Overview

• Name: vraS
• Type: Regulator
• Locus tag: CTB89_RS10440
• Genome accession: NZ_AP017891
• Coordinates: 2062303..2063346 (-)
• Length: 347 a.a.
• NCBI ID: WP_001017131.1
• Uniprot ID: A0A0D1IMN4
• Organism: Staphylococcus aureus strain GN3
• Function: repress expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 2057303..2068346

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
CTB89_RS10410	-	2057724..2058980 (-)	1257	WP_078066285.1	aminopeptidase	-
CTB89_RS10415	-	2058983..2059183 (-)	201	WP_000180460.1	DUF1128 family protein	-
CTB89_RS10420	-	2059330..2059794 (+)	465	WP_000228666.1	low molecular weight protein-tyrosine-phosphatase	-
CTB89_RS10425	-	2059801..2060076 (+)	276	WP_000428172.1	YtxH domain-containing protein	-
CTB89_RS10430	-	2060354..2061571 (+)	1218	WP_000037087.1	YihY/virulence factor BrkB family protein	-
CTB89_RS10435	vraR	2061684..2062313 (-)	630	WP_000153526.1	two-component system response regulator VraR	Regulator
CTB89_RS10440	vraS	2062303..2063346 (-)	1044	WP_001017131.1	sensor histidine kinase	Regulator
CTB89_RS10445	liaF	2063343..2064044 (-)	702	WP_000149064.1	cell wall-active antibiotics response protein LiaF	-
CTB89_RS10450	-	2064059..2064445 (-)	387	WP_001110179.1	hypothetical protein	-
CTB89_RS10455	map	2064662..2065420 (-)	759	WP_000636142.1	type I methionyl aminopeptidase	-
CTB89_RS10460	-	2065890..2066876 (+)	987	WP_000999715.1	aromatic acid exporter family protein	-
CTB89_RS10465	-	2067065..2067478 (-)	414	WP_020977397.1	hypothetical protein	-
CTB89_RS10470	-	2067507..2067617 (-)	111	WP_001790257.1	hypothetical protein	-

Sequence

Protein

• Length: 347 a.a.
• Molecular weight: 40044.52 Da
• Isoelectric Point: 6.0577

>NTDB_id=68429 CTB89_RS10440 WP_001017131.1 2062303..2063346(-) (vraS) [Staphylococcus aureus strain GN3]
MNHYIRTIGSMLILVYSMLAAFLFIDKVFVNIIYFQGMFYTQIFGIPVFLFLNLIIILLCIIVGSVLAYKINQQNDWIKT
QIERSMEGETVGINDQNIEIYSETLDLYHTLVPLNQELHKLRLKTQNLTNENYNINDVKVKKIIEDERQRLARELHDSVS
QQLFAASMMLSAIKETKLEPPLDQQIPILEKMVQDSQLEMRALLLHLRPLGLKDKSLGEGIKDLVIDLQKKVPMKVVHEI
QDFKVPKGIEDHLFRITQEAISNTLRHSNGTKVTVELFNKDDYLLLRIQDNGKGFNVDEKLEQSYGLKNMRERALEIGAT
FHIVSLPDSGTRIEVKAPLNKEDSYDD

Nucleotide

• Length: 1044 bp

>NTDB_id=68429 CTB89_RS10440 WP_001017131.1 2062303..2063346(-) (vraS) [Staphylococcus aureus strain GN3]
ATGAACCACTACATTAGAACAATTGGTTCAATGCTCATCTTAGTATATAGCATGCTAGCTGCATTTCTGTTCATCGATAA
AGTTTTTGTAAATATCATCTATTTTCAAGGTATGTTTTATACACAAATATTCGGAATACCAGTCTTTTTATTTTTAAATC
TCATCATCATATTATTGTGTATTATTGTTGGTTCGGTACTCGCTTACAAAATCAATCAGCAAAATGATTGGATTAAGACG
CAAATTGAGCGTTCAATGGAAGGCGAAACAGTTGGTATTAATGATCAAAATATAGAAATATATAGTGAAACGTTAGATTT
ATACCATACACTCGTACCTTTAAATCAAGAATTGCATAAGTTGCGACTTAAAACTCAAAACTTAACCAATGAAAATTATA
ATATTAATGATGTGAAAGTTAAAAAGATTATTGAAGATGAACGTCAACGACTAGCACGAGAACTTCACGATTCTGTTAGT
CAGCAACTTTTTGCGGCAAGTATGATGCTATCTGCTATCAAAGAAACGAAGTTAGAACCACCATTAGACCAACAAATTCC
GATTTTAGAGAAAATGGTTCAAGATTCGCAGTTAGAAATGCGTGCTTTGCTGTTACATTTAAGACCGCTTGGTTTAAAAG
ACAAATCTTTAGGTGAGGGTATTAAAGATTTAGTTATTGATTTACAAAAAAAAGTGCCAATGAAAGTTGTGCATGAAATA
CAAGATTTTAAAGTGCCTAAAGGTATTGAAGATCATTTGTTCAGAATTACACAGGAAGCAATTTCGAATACATTGCGTCA
TTCAAACGGTACAAAAGTGACAGTAGAATTGTTTAATAAAGACGATTATTTATTGTTGAGAATTCAAGACAATGGTAAAG
GTTTTAATGTTGATGAAAAATTAGAACAAAGTTATGGACTTAAAAATATGCGTGAAAGAGCTTTGGAAATTGGTGCAACG
TTCCATATTGTATCATTGCCAGATTCAGGTACACGTATCGAGGTGAAAGCACCTTTAAATAAGGAGGATTCGTATGACGA
TTAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (249-340)

• Histidine kinase (HisKA_3) (147-210)

3D structure

• AlphaFold DB: A0A0D1IMN4

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vraS	Staphylococcus aureus N315	100	100	1