Detailed information NTG0682985

Bioinformatically predicted

Overview

• Name: disA
• Type: Machinery gene
• Locus tag: OIM89_RS17415
• Genome accession: NZ_CP110079
• Coordinates: 3944310..3945431 (-)
• Length: 373 a.a.
• NCBI ID: WP_010645237.1
• Uniprot ID: A0A385DDD7
• Organism: Streptomyces sp. BI87
• Function: homologous recombination (predicted from homology) Homologous recombination

Genomic Context

Location: 3939310..3950431

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
OIM89_RS17390 (OIM89_17390)	-	3939697..3940365 (-)	669	WP_030698867.1	lipoprotein	-
OIM89_RS17395 (OIM89_17395)	-	3940386..3940925 (-)	540	WP_030698866.1	SigE family RNA polymerase sigma factor	-
OIM89_RS17400 (OIM89_17400)	-	3941144..3942196 (-)	1053	WP_047470995.1	A/G-specific adenine glycosylase	-
OIM89_RS17405 (OIM89_17405)	-	3942309..3943058 (-)	750	WP_030699878.1	phosphatase PAP2 family protein	-
OIM89_RS17410 (OIM89_17410)	-	3943415..3944227 (+)	813	WP_030699877.1	hypothetical protein	-
OIM89_RS17415 (OIM89_17415)	disA	3944310..3945431 (-)	1122	WP_010645237.1	DNA integrity scanning diadenylate cyclase DisA	Machinery gene
OIM89_RS17420 (OIM89_17420)	radA/sms	3945602..3947020 (-)	1419	WP_003948876.1	DNA repair protein RadA	Machinery gene
OIM89_RS17425 (OIM89_17425)	-	3947075..3947650 (-)	576	WP_030699876.1	dihydrofolate reductase family protein	-
OIM89_RS17430 (OIM89_17430)	-	3947909..3949645 (+)	1737	WP_217466555.1	BACON domain-containing protein	-

Sequence

Protein

• Length: 373 a.a.
• Molecular weight: 40215.10 Da
• Isoelectric Point: 5.1034

>NTDB_id=682985 OIM89_RS17415 WP_010645237.1 3944310..3945431(-) (disA) [Streptomyces sp. BI87]
MAANDRATAPGKSGGPGADGLMRASLSAVAPGTQLRDGLERILRGNTGGLIVLGWDKTVESMCTGGFVLDVEFSATRLRE
LCKLDGGIVLDKDLTKILRAGVQLVPDPTIPTDETGTRHRTADRVSKQVNFPVVSVSQSMRLIALYVDGQRRVLEDSAAI
LSRANQALATLERYKLRLDEVAGTLSALEIEDLVTVRDVTAVSQRLEMVRRIAAEIAEYVVELGTDGRLLALQLDELIAG
VEPERELVVRDYVPEPTAKRSRTVDEALAELGKLSHTELLELPVVARALGYTGSPEALDSAVSPRGFRLLAKVPRLPGAI
IDRLVEHFGGLQKLLAASVDDLQTVDGVGEARARSVREGLSRLAESSILERYV

Nucleotide

• Length: 1122 bp

>NTDB_id=682985 OIM89_RS17415 WP_010645237.1 3944310..3945431(-) (disA) [Streptomyces sp. BI87]
GTGGCAGCCAATGACCGGGCAACGGCCCCCGGCAAGTCCGGCGGGCCCGGTGCCGACGGGCTGATGCGTGCCTCGCTGAG
CGCCGTCGCCCCCGGCACCCAGCTGCGGGACGGGCTGGAGCGGATTCTGCGGGGGAACACCGGCGGACTCATCGTGCTCG
GCTGGGACAAGACCGTCGAGTCGATGTGTACCGGCGGCTTCGTGCTGGACGTCGAGTTCTCCGCGACCCGCCTGCGCGAG
CTGTGCAAGCTCGACGGCGGCATCGTCCTCGACAAGGACCTCACCAAGATCCTGCGCGCCGGAGTCCAGCTCGTCCCCGA
CCCGACCATCCCCACCGACGAGACCGGCACCCGGCACCGCACCGCCGACCGCGTCTCCAAGCAGGTCAACTTCCCCGTGG
TCTCGGTCAGCCAGTCGATGCGGCTGATCGCGCTCTACGTGGACGGGCAGCGCCGGGTCCTGGAGGACTCGGCCGCCATC
CTCTCTCGCGCCAACCAGGCTCTCGCCACATTGGAGCGGTACAAGCTCCGGCTGGACGAGGTGGCCGGCACGCTCTCGGC
GCTGGAGATCGAGGACCTGGTCACGGTCCGCGACGTCACGGCCGTCTCGCAGCGGCTGGAGATGGTCCGCCGGATCGCCG
CCGAGATCGCCGAGTACGTGGTGGAACTGGGCACCGACGGGCGGCTGCTCGCCCTCCAGCTGGACGAACTGATCGCCGGC
GTCGAGCCCGAACGCGAGCTGGTCGTCCGGGACTACGTGCCGGAGCCCACGGCGAAGCGTTCCCGCACGGTGGACGAGGC
GCTGGCGGAGCTGGGCAAGCTCAGCCACACCGAGTTGCTCGAACTCCCCGTGGTGGCGCGGGCGCTCGGCTACACCGGCT
CGCCGGAGGCGCTGGACTCGGCGGTGTCGCCGCGCGGCTTCCGCCTCCTGGCGAAGGTGCCGAGGCTGCCCGGCGCCATC
ATCGACCGGCTGGTGGAGCACTTCGGCGGCCTCCAGAAGCTGCTGGCGGCCAGCGTGGACGACCTCCAGACGGTGGACGG
CGTCGGCGAGGCCCGTGCCCGCAGCGTCCGCGAGGGCCTCTCCCGCCTGGCCGAGTCGTCGATCCTGGAGCGGTACGTCT
GA

Domains

Predicted by InterProScan.

• DisA bacterial checkpoint controller nucleotide-binding (DAC) (37-150)

• DisA bacterial checkpoint controller linker region (DisA-linker) (154-296)

• Helix-hairpin-helix motif (HHH_2) (323-358)

3D structure

• AlphaFold DB: A0A385DDD7

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
disA	Bacillus subtilis subsp. subtilis str. 168	46.532	92.761	0.432