Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   OIM89_RS16120 Genome accession   NZ_CP110079
Coordinates   3658784..3659443 (-) Length   219 a.a.
NCBI ID   WP_030700270.1    Uniprot ID   A0A7Y6KI63
Organism   Streptomyces sp. BI87     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 3653784..3664443
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  OIM89_RS16085 (OIM89_16085) tgmB 3654123..3655077 (-) 955 Protein_3170 ATP-grasp ribosomal peptide maturase -
  OIM89_RS16090 (OIM89_16090) tgmA 3655085..3655330 (-) 246 WP_264491377.1 putative ATP-grasp-modified RiPP -
  OIM89_RS16095 (OIM89_16095) - 3655460..3655678 (-) 219 WP_226965478.1 hypothetical protein -
  OIM89_RS16100 (OIM89_16100) - 3655675..3655872 (-) 198 WP_030699893.1 hypothetical protein -
  OIM89_RS16105 (OIM89_16105) - 3655869..3656309 (-) 441 WP_264491792.1 ATP-binding protein -
  OIM89_RS16110 (OIM89_16110) - 3656654..3657931 (+) 1278 WP_264491378.1 XRE family transcriptional regulator -
  OIM89_RS16115 (OIM89_16115) - 3657928..3658467 (+) 540 WP_226965476.1 GNAT family N-acetyltransferase -
  OIM89_RS16120 (OIM89_16120) vraR 3658784..3659443 (-) 660 WP_030700270.1 response regulator Regulator
  OIM89_RS16125 (OIM89_16125) - 3659452..3660759 (-) 1308 WP_175458335.1 sensor histidine kinase -
  OIM89_RS16130 (OIM89_16130) - 3661151..3661726 (+) 576 WP_030700149.1 GlcG/HbpS family heme-binding protein -
  OIM89_RS16135 (OIM89_16135) - 3661767..3662387 (+) 621 WP_195730786.1 ankyrin repeat domain-containing protein -
  OIM89_RS16140 (OIM89_16140) - 3662429..3662836 (-) 408 WP_030700147.1 RidA family protein -
  OIM89_RS16145 (OIM89_16145) - 3663009..3663389 (+) 381 WP_030700146.1 winged helix-turn-helix transcriptional regulator -
  OIM89_RS16150 (OIM89_16150) - 3663393..3664085 (-) 693 WP_047470489.1 hypothetical protein -
  OIM89_RS29870 - 3664244..3664348 (-) 105 WP_234479791.1 DUF397 domain-containing protein -

Sequence

Protein


Download         Length: 219 a.a.        Molecular weight: 23629.05 Da        Isoelectric Point: 6.4988

>NTDB_id=682980 OIM89_RS16120 WP_030700270.1 3658784..3659443(-) (vraR) [Streptomyces sp. BI87]
MPAATDEPPTPHPVRLLLCDDHAVVRAGLRALLSSAPGIEVVAEAGSGEEALALTTLHHPDLVLMDLQLGEGIDGVETTR
RLTTLPDHPPYVLVLTTYDTDADITRAVEAGATGYLLKAERPEELFTAIRAAASGRTALSPPVAQRVMTHLRNPQPELTP
RERDILRHLTQGLGNREIARALFISEATVKTHLGRIYQKLGVETRSGAVAVGKERRLLG

Nucleotide


Download         Length: 660 bp        

>NTDB_id=682980 OIM89_RS16120 WP_030700270.1 3658784..3659443(-) (vraR) [Streptomyces sp. BI87]
GTGCCCGCCGCCACCGACGAGCCGCCCACCCCTCACCCCGTCCGCCTCCTCCTCTGCGACGACCACGCCGTGGTCCGCGC
CGGCCTGCGCGCCCTCCTCTCCAGCGCCCCCGGCATCGAGGTCGTAGCCGAAGCAGGCAGCGGCGAAGAAGCCCTCGCCC
TCACCACCCTCCACCACCCCGACCTGGTCCTCATGGACCTCCAACTAGGCGAAGGAATCGACGGAGTCGAGACCACCCGC
CGCCTCACCACCCTCCCCGACCACCCCCCGTACGTCCTCGTCCTCACCACCTACGACACCGACGCCGACATCACCCGAGC
CGTCGAAGCGGGCGCCACCGGCTACCTGCTCAAGGCCGAACGCCCTGAAGAGCTCTTCACGGCCATCAGGGCTGCGGCAT
CGGGGCGTACGGCGTTGTCGCCGCCTGTGGCACAGAGGGTGATGACTCACTTGCGGAACCCGCAGCCCGAGCTGACGCCG
AGGGAGCGGGACATTTTGCGGCACCTTACGCAGGGGCTGGGGAACCGGGAGATCGCCAGGGCGTTGTTCATCAGCGAGGC
GACGGTGAAGACCCATCTGGGCCGGATCTATCAGAAGTTGGGGGTGGAGACGCGGTCGGGGGCGGTGGCTGTGGGGAAGG
AGCGGCGGTTGTTGGGGTGA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(17-130)

Bacterial regulatory proteins, luxR family (GerE)

(158-210)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A7Y6KI63

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

37.559

97.26

0.365