Detailed information    

insolico Bioinformatically predicted

Overview

Name   comB4   Type   Machinery gene
Locus tag   HPATCC43504_RS01045 Genome accession   NZ_AP017632
Coordinates   221672..224035 (+) Length   787 a.a.
NCBI ID   WP_108169543.1    Uniprot ID   -
Organism   Helicobacter pylori strain ATCC 43504     
Function   transformation-associated type IV transport system (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 216672..229035
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  HPATCC43504_RS01015 (HPATCC43504_00206) groES 216701..217057 (-) 357 WP_000671927.1 co-chaperone GroES -
  HPATCC43504_RS01020 (HPATCC43504_00207) dnaG 217335..219014 (+) 1680 WP_108169539.1 DNA primase -
  HPATCC43504_RS01025 (HPATCC43504_00208) - 219011..220063 (+) 1053 WP_108169540.1 MnmA/TRMU family protein -
  HPATCC43504_RS01030 (HPATCC43504_00209) - 220153..220980 (+) 828 WP_108169541.1 DUF5718 family protein -
  HPATCC43504_RS01035 (HPATCC43504_00210) comB2 221126..221407 (+) 282 WP_001272690.1 TrbC/VirB2 family protein Machinery gene
  HPATCC43504_RS01040 (HPATCC43504_00211) comB3 221407..221670 (+) 264 WP_108169542.1 competence protein ComB Machinery gene
  HPATCC43504_RS01045 (HPATCC43504_00212) comB4 221672..224035 (+) 2364 WP_108169543.1 VirB4 family type IV secretion/conjugal transfer ATPase Machinery gene
  HPATCC43504_RS01055 (HPATCC43504_00213) - 224354..225694 (+) 1341 WP_162296840.1 COG3014 family protein -
  HPATCC43504_RS01060 (HPATCC43504_00214) cheV1 225795..226760 (+) 966 WP_000785454.1 chemotaxis protein CheV1 -
  HPATCC43504_RS01065 (HPATCC43504_00215) nspC 226757..227974 (+) 1218 WP_108169545.1 carboxynorspermidine decarboxylase -
  HPATCC43504_RS01070 (HPATCC43504_00216) lpxE 227984..228517 (-) 534 WP_231952923.1 lipid A 1-phosphatase LpxE -

Sequence

Protein


Download         Length: 787 a.a.        Molecular weight: 90313.94 Da        Isoelectric Point: 8.8662

>NTDB_id=68270 HPATCC43504_RS01045 WP_108169543.1 221672..224035(+) (comB4) [Helicobacter pylori strain ATCC 43504]
MLEKLLSAIKQKVSNYFLGVLPKSYSMSEENNILGLYDEYFLLTKNENLVGILRLEGVSYTHLSTEQLQDLFTERQMALD
SLEKVVARLVVKRRKIDHQQNIQTDSKYLQAILNQFENKEVYENQYFLVLESAHSLQGVLEHKKKSLMHANRENFKDILS
YKAHFLQETLKSLEIQLKNYAPKLLSSKEVLNFYAEYINGFDLPLKPLVGGYLSDSYIASSITFEKDYFIQESFNQKTYN
RLIGIKAYESERITSIAIGALLYQETPLDIIFSIEPMSVNKTLGFLKERAKFSMSNLVKNELLEYQELVKTKRLSMQKFA
LNILIKAPSLEDLDAQTSLVLGLLFKENLVGVIETFGLKGGYFSFFPERIHLNHRLRFLTSKALACLMVFERQNLGFKAN
SWGNSPLSVFKNLDYSPFLFNFHNQEVSHNNAKEIARVNGHTLIIGATGSGKSTLISFLMMSALKYQNMRLLAFDRMQGL
YSFTKFFKGHYHDGKSFSINPFCLEPNLQNLEFLQSFFLSMFDLAPSRDKEALEDMNAIFSAIKSLYETLYPKAFSLLDF
KETLKRTSSNQLGLSLEPYLNNPLFNALNDAFNSNAFLNVINLDTITQNPKDLGLLAYYLFYKILEESRKNDSGFLVFLD
EFKSYVENDLLNTKINALITQARKANGVVVLALQDIYQLSGVKNAHSFLSNMGTLILYPQKNARELKHHFNVPLSETEIS
FLENTPLYARQVLVKNLGNGNSNMIDVSLESLGRYLKIFNSDSSHVNKVKALQKDYPTEWREKLLKS

Nucleotide


Download         Length: 2364 bp        

>NTDB_id=68270 HPATCC43504_RS01045 WP_108169543.1 221672..224035(+) (comB4) [Helicobacter pylori strain ATCC 43504]
ATGTTAGAAAAGCTTTTGAGCGCTATCAAACAAAAGGTTTCAAACTATTTTTTAGGGGTTTTGCCTAAAAGCTATTCTAT
GAGCGAAGAAAACAACATTTTAGGCTTGTATGATGAGTATTTTTTACTCACTAAAAACGAAAACTTAGTGGGCATCCTCC
GTTTAGAGGGGGTGAGTTACACCCATTTAAGCACAGAGCAATTGCAAGATCTCTTCACCGAGCGCCAAATGGCGTTGGAT
TCTTTAGAAAAAGTCGTGGCGCGCCTTGTGGTTAAAAGGCGTAAAATTGATCACCAACAAAACATTCAAACTGACTCTAA
ATACTTGCAAGCGATTTTGAATCAATTTGAAAACAAAGAGGTGTATGAAAATCAGTATTTTTTAGTTTTAGAAAGCGCGC
ATTCTTTACAGGGCGTTTTAGAGCATAAGAAAAAATCCTTAATGCATGCCAATAGGGAAAATTTTAAGGACATTCTCTCT
TATAAAGCGCATTTTTTGCAAGAAACTTTAAAAAGCTTAGAAATCCAGCTCAAAAACTATGCCCCCAAACTCTTAAGCTC
CAAAGAGGTTTTGAATTTTTATGCGGAATACATTAACGGGTTTGATCTCCCCTTAAAGCCCCTAGTAGGGGGGTATTTGA
GCGATAGTTATATCGCTAGTTCTATCACTTTTGAAAAAGATTATTTCATTCAAGAAAGCTTTAATCAAAAAACCTATAAC
CGCTTGATTGGCATTAAAGCTTATGAGAGCGAGCGCATCACTTCTATAGCGATCGGAGCGCTTTTATACCAAGAGACGCC
ACTAGATATTATCTTTTCTATAGAGCCTATGAGCGTCAATAAAACGCTGGGTTTTTTAAAAGAGAGGGCCAAGTTTAGCA
TGTCCAATCTCGTTAAAAACGAGCTGCTAGAATACCAAGAATTAGTCAAAACCAAACGCCTATCCATGCAAAAATTCGCC
CTAAACATTCTTATCAAAGCCCCCAGTTTAGAGGATTTAGACGCTCAAACGAGCTTAGTTTTAGGGCTTTTATTTAAAGA
AAATTTAGTGGGCGTTATAGAAACTTTTGGCTTGAAAGGGGGGTATTTTTCCTTTTTCCCTGAACGCATCCACTTAAACC
ACCGCTTGCGTTTTTTAACCTCTAAAGCCTTAGCGTGTTTAATGGTGTTTGAAAGGCAAAATTTAGGCTTTAAGGCTAAT
TCATGGGGGAATAGCCCTTTGAGCGTGTTTAAAAATTTGGATTATTCCCCTTTTTTATTCAATTTCCACAACCAAGAAGT
GAGCCACAACAACGCTAAAGAAATCGCCAGAGTGAATGGGCATACTTTAATCATAGGGGCTACCGGGAGCGGTAAAAGCA
CGCTGATTAGCTTTTTAATGATGAGCGCTTTGAAATACCAAAACATGCGCCTTTTAGCCTTTGACAGGATGCAGGGGCTG
TATTCTTTCACAAAATTTTTTAAAGGGCATTACCATGACGGCAAATCTTTTAGCATCAACCCCTTTTGTTTAGAACCTAA
TTTGCAGAATTTAGAATTTTTGCAATCCTTCTTTTTGAGCATGTTTGATCTTGCCCCTTCAAGGGATAAAGAAGCCTTGG
AAGATATGAATGCGATTTTTAGCGCGATTAAGAGCCTTTATGAGACCTTATACCCTAAAGCTTTTAGTTTGCTAGACTTT
AAAGAAACGCTTAAAAGAACTTCGTCTAACCAATTGGGCTTGAGTTTGGAGCCGTATTTGAATAACCCCCTTTTTAACGC
TTTGAATGACGCGTTCAACTCCAACGCTTTTTTAAATGTGATAAACCTAGACACCATCACCCAAAACCCCAAAGACTTAG
GGCTTTTAGCCTATTACTTGTTTTATAAAATCTTAGAAGAATCCAGGAAAAACGACAGCGGTTTTTTGGTTTTTTTAGAC
GAGTTTAAATCCTATGTGGAAAACGATTTGCTGAACACCAAAATTAACGCTTTAATCACGCAAGCCAGAAAAGCTAATGG
CGTGGTGGTGTTGGCTTTGCAAGATATTTACCAATTAAGTGGGGTTAAAAACGCTCATAGTTTTTTGAGCAACATGGGGA
CTCTTATTTTGTATCCGCAAAAAAACGCTAGGGAGTTGAAGCACCATTTCAATGTGCCTTTGAGCGAAACTGAAATTTCT
TTTTTAGAAAACACCCCCTTGTATGCCAGGCAGGTTTTAGTCAAAAATCTGGGTAATGGGAATTCTAACATGATTGATGT
GAGTTTAGAAAGTTTAGGGCGTTATTTGAAAATCTTTAATTCAGACTCTAGCCATGTGAATAAAGTGAAAGCGTTACAAA
AAGACTACCCTACAGAGTGGCGTGAGAAACTTTTGAAGAGCTAG

Domains

Predicted by InterproScan.

FtsK/SpoIIIE family (FtsK_SpoIIIE)

(426-466)

CagE, TrbE, VirB family, component of type IV transporter system (CagE_TrbE_VirB)

(176-375)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comB4 Helicobacter pylori 26695

98.094

100

0.981

Multiple sequence alignment