Detailed information NTG0068213

Bioinformatically predicted

Overview

• Name: cytR
• Type: Regulator
• Locus tag: JLF34_RS22880
• Genome accession: NZ_AP022536
• Coordinates: 4821620..4822645 (+)
• Length: 341 a.a.
• NCBI ID: WP_000644904.1
• Uniprot ID: P0ACN8
• Organism: Escherichia coli strain THO-008
• Function: promote competence gene expression (predicted from homology) Competence regulation

Genomic Context

Location: 4816620..4827645

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
JLF34_RS22860 (THOESC008_44120)	metJ	4817805..4818122 (+)	318	WP_000852812.1	met regulon transcriptional regulator MetJ	-
JLF34_RS22865 (THOESC008_44130)	yiiX	4818182..4818790 (+)	609	WP_001577479.1	YiiX family permuted papain-like enzyme	-
JLF34_RS22870 (THOESC008_44140)	rpmE	4818851..4819063 (-)	213	WP_000710769.1	50S ribosomal protein L31	-
JLF34_RS22875 (THOESC008_44150)	priA	4819266..4821464 (+)	2199	WP_001586520.1	primosomal protein N'	Machinery gene
JLF34_RS22880 (THOESC008_44160)	cytR	4821620..4822645 (+)	1026	WP_000644904.1	DNA-binding transcriptional regulator CytR	Regulator
JLF34_RS22885 (THOESC008_44170)	ftsN	4822737..4823696 (+)	960	WP_000068828.1	cell division protein FtsN	-
JLF34_RS22890 (THOESC008_44180)	hslV	4823789..4824319 (+)	531	WP_000208242.1	ATP-dependent protease subunit HslV	-
JLF34_RS22895 (THOESC008_44190)	hslU	4824329..4825660 (+)	1332	WP_001293344.1	HslU--HslV peptidase ATPase subunit	-
JLF34_RS22900 (THOESC008_44200)	menA	4825727..4826653 (+)	927	WP_000139496.1	1,4-dihydroxy-2-naphthoate polyprenyltransferase	-
JLF34_RS22905 (THOESC008_44210)	rraA	4826746..4827231 (+)	486	WP_000872908.1	ribonuclease E activity regulator RraA	-
JLF34_RS22910 (THOESC008_44220)	zapB	4827316..4827561 (-)	246	WP_001296623.1	septal ring assembly protein ZapB	-

Sequence

Protein

• Length: 341 a.a.
• Molecular weight: 37819.78 Da
• Isoelectric Point: 6.3842

>NTDB_id=68213 JLF34_RS22880 WP_000644904.1 4821620..4822645(+) (cytR) [Escherichia coli strain THO-008]
MKAKKQETAATMKDVALKAKVSTATVSRALMNPDKVSQATRNRVEKAAREVGYLPQPMGRNVKRNESRTILVIVPDICDP
FFSEIIRGIEVTAANHGYLVLIGDCAHQNQQEKTFIDLIITKQIDGMLLLGSRLPFDASIEEQRNLPPMVMANEFAPELE
LPTVHIDNLTAAFDAVNYLYEQGHKRIGCIAGPEEMPLCHYRLQGYVQALRRCGIMVDPQYIARGDFTFEAGSKAMQQLL
DLPQPPTAVFCHSDVMALGALSQAKRQGLKVPEDLSIIGFDNIDLTQFCDPPLTTIAQPRYEIGREAMLLLLDQMQGQHV
GSGSRLMDCELIIRGSTRALP

Nucleotide

• Length: 1026 bp

>NTDB_id=68213 JLF34_RS22880 WP_000644904.1 4821620..4822645(+) (cytR) [Escherichia coli strain THO-008]
GTGAAAGCGAAGAAGCAGGAAACTGCCGCGACCATGAAAGACGTTGCCCTCAAGGCAAAAGTCTCTACAGCGACCGTCTC
CCGAGCATTAATGAATCCCGATAAAGTCTCCCAGGCCACCCGTAATCGGGTTGAAAAAGCGGCCCGGGAAGTGGGTTATT
TACCGCAGCCTATGGGGCGCAACGTCAAGCGTAATGAATCCCGCACCATTCTGGTGATTGTCCCGGATATCTGCGATCCC
TTCTTTAGCGAAATTATTCGCGGTATCGAAGTTACGGCGGCAAATCACGGATATCTGGTGCTGATTGGCGACTGTGCGCA
TCAAAATCAGCAGGAAAAAACCTTTATCGATTTGATCATCACCAAGCAAATTGATGGCATGTTGTTGCTTGGTTCAAGGC
TGCCGTTTGATGCCAGCATTGAGGAACAGCGTAATCTGCCGCCGATGGTGATGGCGAACGAATTTGCACCGGAACTGGAG
CTGCCTACCGTTCATATCGACAATCTGACCGCCGCATTTGATGCAGTAAATTATTTATATGAGCAAGGGCATAAACGGAT
TGGTTGTATAGCCGGTCCCGAAGAGATGCCGCTGTGTCACTACCGCCTGCAAGGCTACGTTCAGGCGCTGCGTCGCTGCG
GCATTATGGTTGATCCGCAATACATCGCCCGTGGCGACTTCACCTTCGAAGCCGGAAGCAAAGCAATGCAACAGCTGCTT
GATCTTCCACAACCGCCTACTGCTGTCTTCTGCCATAGCGATGTGATGGCGCTCGGCGCACTTTCTCAGGCAAAACGCCA
GGGGCTGAAAGTCCCGGAAGACCTTTCCATAATCGGTTTTGATAACATCGACCTGACGCAATTTTGTGATCCGCCGCTGA
CAACCATCGCGCAGCCGCGTTACGAAATCGGTCGGGAAGCTATGCTGTTATTGCTTGATCAAATGCAGGGGCAACACGTT
GGCAGTGGCTCTCGTTTAATGGACTGCGAACTTATCATCCGGGGATCAACACGCGCGTTACCTTAA

Domains

Predicted by InterProScan.

• Bacterial regulatory proteins, lacI family (LacI) (11-56)

• Periplasmic binding protein-like domain (Peripla_BP_3) (176-337)

3D structure

• AlphaFold DB: P0ACN8

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
cytR	Vibrio parahaemolyticus RIMD 2210633	64.179	98.24	0.63
cytR	Vibrio cholerae C6706	65.443	95.894	0.628