Detailed information    

insolico Bioinformatically predicted

Overview

Name   ccrB   Type   Machinery gene
Locus tag   ATE38_RS00225 Genome accession   NZ_AP017377
Coordinates   47841..49469 (-) Length   542 a.a.
NCBI ID   WP_001186608.1    Uniprot ID   -
Organism   Staphylococcus aureus strain OC8     
Function   promote SCCmec transfer (predicted from homology)   
Homologous recombination

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
ICE 25826..94452 47841..49469 within 0
SCCmec 41077..56011 47841..49469 within 0


Gene organization within MGE regions


Location: 25826..94452
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ATE38_RS00115 yycF 26284..26985 (+) 702 WP_000101976.1 response regulator YycF -
  ATE38_RS00120 walK 26998..28824 (+) 1827 WP_000871607.1 cell wall metabolism sensor histidine kinase WalK -
  ATE38_RS00125 yycH 28817..30151 (+) 1335 WP_001060131.1 two-component system activity regulator YycH -
  ATE38_RS00130 yycI 30152..30940 (+) 789 WP_001104172.1 two-component system regulatory protein YycI -
  ATE38_RS00135 - 31330..32130 (+) 801 WP_000088648.1 MBL fold metallo-hydrolase -
  ATE38_RS00140 adsA 32358..34676 (+) 2319 WP_000645780.1 LPXTG-anchored adenosine synthase AdsA -
  ATE38_RS00145 rlmH 35044..35523 (+) 480 WP_000704775.1 23S rRNA (pseudouridine(1915)-N(3))-methyltransferase RlmH -
  ATE38_RS00150 - 35845..37101 (+) 1257 WP_000566670.1 DUF3578 domain-containing protein -
  ATE38_RS00155 - 37516..37755 (+) 240 WP_001282728.1 hypothetical protein -
  ATE38_RS00160 - 37787..38461 (-) 675 WP_001106057.1 IS6-like element IS257 family transposase -
  ATE38_RS00165 - 38545..38886 (+) 342 WP_001797647.1 hydroxymethylglutaryl-CoA synthase -
  ATE38_RS00175 - 39763..40506 (+) 744 WP_000958858.1 glycerophosphoryl diester phosphodiesterase -
  ATE38_RS00180 - 40603..41031 (+) 429 WP_000872606.1 MaoC family dehydratase -
  ATE38_RS00185 mecA 41077..43086 (-) 2010 WP_001801873.1 PBP2a family beta-lactam-resistant peptidoglycan transpeptidase MecA -
  ATE38_RS00190 - 43183..44169 (+) 987 WP_001549960.1 beta-lactam sensor/signal transducer MecR1 -
  ATE38_RS00195 - 44141..44401 (+) 261 WP_001549961.1 type I restriction enzyme endonuclease domain-containing protein -
  ATE38_RS00200 - 44409..45998 (-) 1590 Protein_34 IS1182 family transposase -
  ATE38_RS00205 - 46050..46556 (-) 507 WP_001092189.1 DUF1643 domain-containing protein -
  ATE38_RS00210 - 46571..46882 (-) 312 WP_000700851.1 DUF960 family protein -
  ATE38_RS00220 - 46969..47319 (-) 351 WP_000849672.1 SAUGI family uracil-DNA glycosylase inhibitor -
  ATE38_RS00225 ccrB 47841..49469 (-) 1629 WP_001186608.1 recombinase family protein Machinery gene
  ATE38_RS00230 ccrA 49491..50840 (-) 1350 WP_000815640.1 recombinase family protein Machinery gene
  ATE38_RS00235 - 51074..52867 (-) 1794 WP_024937223.1 DUF927 domain-containing protein -
  ATE38_RS00240 - 52867..53163 (-) 297 WP_000273823.1 single-stranded DNA-binding protein -
  ATE38_RS00245 - 53356..54402 (-) 1047 WP_001042023.1 hypothetical protein -
  ATE38_RS00250 - 54857..56011 (+) 1155 WP_000912116.1 ATP-binding protein -
  ATE38_RS00255 - 56041..56841 (+) 801 WP_000749912.1 abortive infection family protein -
  ATE38_RS00260 - 57130..57264 (-) 135 WP_001790628.1 hypothetical protein -
  ATE38_RS00265 - 57228..57320 (+) 93 WP_001790000.1 hypothetical protein -
  ATE38_RS00270 - 57467..59214 (+) 1748 Protein_47 DUF6119 family protein -
  ATE38_RS00275 - 59308..59760 (-) 453 Protein_48 tRNA-dihydrouridine synthase -
  ATE38_RS00280 - 59776..59877 (-) 102 WP_001791873.1 hypothetical protein -
  ATE38_RS15180 - 60110..60646 (-) 537 WP_078068031.1 IS30 family transposase -
  ATE38_RS15185 - 60627..61130 (-) 504 WP_000746372.1 transposase -
  ATE38_RS00290 - 61239..61580 (-) 342 WP_001255377.1 cystatin-like fold lipoprotein -
  ATE38_RS00295 - 61636..62226 (-) 591 WP_000810443.1 hypothetical protein -
  ATE38_RS00300 - 62233..63279 (-) 1047 WP_000247465.1 CHAP domain-containing protein -
  ATE38_RS00305 - 63269..65116 (-) 1848 WP_024937193.1 membrane protein -
  ATE38_RS00310 - 65121..66479 (-) 1359 WP_024937192.1 FtsK/SpoIIIE domain-containing protein -
  ATE38_RS00315 - 66533..69028 (-) 2496 WP_001049264.1 ATP-binding protein -
  ATE38_RS00320 - 69063..69446 (-) 384 WP_000358144.1 TcpE family conjugal transfer membrane protein -
  ATE38_RS00325 - 69458..69718 (-) 261 WP_000015639.1 TcpD family membrane protein -
  ATE38_RS00330 - 69723..70778 (-) 1056 WP_000692002.1 conjugal transfer protein -
  ATE38_RS00335 - 70839..71930 (-) 1092 WP_000172938.1 replication initiation factor domain-containing protein -
  ATE38_RS00340 - 72105..72407 (-) 303 WP_000386891.1 hypothetical protein -
  ATE38_RS00345 - 72421..72741 (-) 321 WP_000805733.1 DUF961 family protein -
  ATE38_RS00350 - 72892..73176 (-) 285 WP_000134541.1 hypothetical protein -
  ATE38_RS00355 - 73317..74072 (-) 756 WP_000355845.1 sulfite exporter TauE/SafE family protein -
  ATE38_RS00360 cstR 74072..74332 (-) 261 WP_001105087.1 persulfide-sensing transcriptional repressor CstR -
  ATE38_RS00365 cstA 74469..75536 (+) 1068 WP_000816129.1 persulfide response sulfurtransferase CstA -
  ATE38_RS00370 cstB 75567..76901 (+) 1335 WP_000465472.1 persulfide dioxygenase-sulfurtransferase CstB -
  ATE38_RS00375 sqr 76920..78113 (+) 1194 WP_001033018.1 type II sulfide:quinone oxidoreductase Sqr -
  ATE38_RS15475 - 78380..78585 (-) 206 Protein_70 universal stress protein -
  ATE38_RS00390 - 78779..79765 (-) 987 WP_000662031.1 tRNA-dihydrouridine synthase -
  ATE38_RS00395 - 80074..80277 (+) 204 WP_000398679.1 DUF6007 family protein -
  ATE38_RS00400 - 80326..80622 (+) 297 WP_000201640.1 TfoX/Sxy family protein -
  ATE38_RS00405 - 80694..81914 (-) 1221 WP_000130765.1 MFS transporter -
  ATE38_RS00410 - 81907..82457 (-) 551 Protein_75 flavodoxin family protein -
  ATE38_RS00415 - 82570..83430 (+) 861 WP_001052510.1 LysR family transcriptional regulator -
  ATE38_RS00420 - 83785..84318 (-) 534 WP_000543163.1 DUF4865 family protein -
  ATE38_RS00425 - 84409..85152 (+) 744 WP_001793250.1 LysR family transcriptional regulator -
  ATE38_RS00430 - 85586..86188 (+) 603 WP_096377461.1 hypothetical protein -
  ATE38_RS00435 - 86455..89607 (+) 3153 WP_000080559.1 DEAD/DEAH box helicase -
  ATE38_RS00440 - 89664..90146 (+) 483 WP_000410568.1 hypothetical protein -
  ATE38_RS00445 - 90351..91337 (+) 987 WP_000710576.1 phosphatidylinositol-specific phospholipase C -
  ATE38_RS00450 - 91558..92328 (+) 771 WP_000977774.1 tandem-type lipoprotein -
  ATE38_RS00455 - 92380..93150 (+) 771 WP_000597212.1 tandem-type lipoprotein -
  ATE38_RS00460 - 93214..93984 (+) 771 WP_000977781.1 tandem-type lipoprotein -

Sequence

Protein


Download         Length: 542 a.a.        Molecular weight: 62654.83 Da        Isoelectric Point: 9.7970

>NTDB_id=67849 ATE38_RS00225 WP_001186608.1 47841..49469(-) (ccrB) [Staphylococcus aureus strain OC8]
MQQLKTKRVGIYVRVSTEMQSTEGYSIDGQINQIKEYCDFHHFEVKDIYADRGISGKSMNRPELQRMLKDAKEGNIDCVM
VYKTNRLARNTSDLLKIVEDLHKQNVEFFSLSERMEVNTSSGKLMLQILASFSEFERNNIVENVFMGQTRRAQEGYYQGN
LPLGYDKIPDSKHELMINQHEANIVKYIFECYAKGHGYRKIANALNHKGYVTKKGKPFSISSITYILANPFYIGKIQFAK
YKDWSEKRRKGLNDKPVIAEGKHSPIINQDLWDKVQMRKKQVSQKPQVHGKGTNLLTGIIHCPQCGAPMAASNTTNTLKD
GTKKRIRYYSCSNFRNKGSKVCSANSVRADVIEDYVMKQILEIVKSDKVIQRVVTHVNQENQVDGAALHHDIAYKQQQYD
EVQIKINNLIKTIEDNPDLTSVIRPSIQKYEKQLNDITNQINQLKNQQNEDKTLFDAKEISKLLQHIFHDIKHIEKSRLK
ALYLSVIDRIDIKKDGNHKKQFYVTLKLNNEIIKQLFNNKQLDEVHLSTSSLFLPQTLYLTI

Nucleotide


Download         Length: 1629 bp        

>NTDB_id=67849 ATE38_RS00225 WP_001186608.1 47841..49469(-) (ccrB) [Staphylococcus aureus strain OC8]
ATGCAACAACTTAAAACAAAACGTGTCGGTATCTATGTACGTGTATCAACAGAAATGCAAAGCACAGAAGGTTATAGTAT
CGACGGACAAATCAATCAAATCAAAGAATACTGTGACTTCCATCATTTTGAAGTTAAAGATATATACGCTGACCGTGGTA
TTTCAGGTAAATCTATGAACAGACCTGAGCTCCAACGTATGTTGAAAGATGCAAAAGAAGGCAATATCGACTGTGTTATG
GTATACAAAACAAACCGATTAGCTCGTAATACATCTGATCTTCTCAAAATTGTCGAAGATTTACACAAACAAAATGTCGA
ATTTTTCAGTTTGTCAGAGCGTATGGAAGTCAATACTTCTTCTGGTAAACTCATGTTACAGATACTTGCGAGTTTCTCAG
AATTCGAACGTAATAACATTGTCGAGAACGTATTTATGGGTCAAACGAGACGTGCCCAAGAAGGCTATTATCAAGGCAAT
TTACCACTAGGTTATGACAAAATACCAGATAGTAAACACGAGCTAATGATTAACCAACATGAAGCTAATATTGTAAAATA
TATATTCGAGTGCTATGCCAAAGGACATGGCTATCGTAAAATTGCCAATGCATTGAATCACAAAGGATATGTCACTAAAA
AGGGGAAACCTTTCAGTATTAGTTCAATCACATACATCTTAGCTAACCCTTTCTATATCGGCAAAATTCAATTTGCGAAA
TACAAAGATTGGAGTGAAAAACGTCGTAAAGGGCTGAATGATAAACCAGTGATAGCTGAAGGTAAGCATTCCCCCATTAT
TAATCAAGATTTATGGGATAAAGTACAAATGCGTAAGAAACAAGTCAGTCAAAAACCCCAAGTCCATGGCAAAGGAACGA
ATCTGCTTACAGGCATTATTCACTGTCCCCAATGTGGCGCACCTATGGCAGCAAGCAATACCACGAATACTCTTAAAGAC
GGGACTAAGAAACGTATTCGTTACTATTCATGTAGTAATTTTCGGAACAAGGGTTCCAAAGTATGTTCGGCAAACAGTGT
AAGAGCTGATGTGATTGAAGATTATGTGATGAAGCAAATACTTGAAATAGTCAAAAGTGATAAAGTCATTCAACGCGTAG
TAACACACGTCAATCAAGAAAATCAAGTTGATGGCGCTGCACTTCATCACGATATTGCTTATAAGCAACAACAATATGAT
GAAGTACAAATCAAAATAAATAACTTGATTAAAACCATCGAGGATAATCCGGACTTAACATCAGTAATCAGACCAAGTAT
TCAAAAATATGAAAAGCAACTCAATGACATTACGAATCAAATCAACCAACTCAAAAATCAACAAAATGAAGATAAGACTT
TATTTGATGCCAAAGAAATCAGTAAACTATTACAACACATCTTTCATGATATTAAGCACATAGAAAAATCTCGACTCAAA
GCATTGTATCTATCAGTGATTGATCGCATTGATATTAAAAAAGATGGTAATCATAAAAAACAATTCTATGTCACACTCAA
ACTTAATAACGAAATCATTAAACAACTTTTCAATAATAAACAACTCGACGAAGTGCATCTCAGCACTTCGTCTTTATTTT
TGCCCCAAACACTATATCTTACTATTTAG

Domains

Predicted by InterproScan.

Recombinase (Recombinase)

(180-280)

Resolvase, N terminal domain (Resolvase)

(11-156)

Ogr/Delta-like zinc finger (Ogr_Delta)

(301-356)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  ccrB Staphylococcus aureus N315

98.893

100

0.989

Multiple sequence alignment