Detailed information    

insolico Bioinformatically predicted

Overview

Name   disA   Type   Machinery gene
Locus tag   OG574_RS22405 Genome accession   NZ_CP109485
Coordinates   4914011..4915135 (+) Length   374 a.a.
NCBI ID   WP_100597752.1    Uniprot ID   -
Organism   Streptomyces sp. NBC_01445     
Function   homologous recombination (predicted from homology)   
Homologous recombination

Genomic Context

Location: 4909011..4920135
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  OG574_RS22390 (OG574_22370) - 4909725..4910465 (+) 741 WP_326778579.1 hypothetical protein -
  OG574_RS22395 (OG574_22375) - 4910498..4912213 (-) 1716 WP_326774663.1 hypothetical protein -
  OG574_RS22400 (OG574_22380) radA/sms 4912458..4913867 (+) 1410 WP_100597753.1 DNA repair protein RadA Machinery gene
  OG574_RS22405 (OG574_22385) disA 4914011..4915135 (+) 1125 WP_100597752.1 DNA integrity scanning diadenylate cyclase DisA Machinery gene
  OG574_RS22410 (OG574_22390) - 4915468..4916268 (-) 801 WP_326774664.1 hypothetical protein -
  OG574_RS22415 (OG574_22395) - 4916454..4917095 (+) 642 WP_326774665.1 phosphatase PAP2 family protein -
  OG574_RS22420 (OG574_22400) - 4917096..4917743 (-) 648 WP_326774666.1 response regulator transcription factor -
  OG574_RS22425 (OG574_22405) - 4917740..4919338 (-) 1599 WP_326774667.1 histidine kinase -

Sequence

Protein


Download         Length: 374 a.a.        Molecular weight: 40301.14 Da        Isoelectric Point: 4.9269

>NTDB_id=677483 OG574_RS22405 WP_100597752.1 4914011..4915135(+) (disA) [Streptomyces sp. NBC_01445]
MAANDRAAAPGKSGGSSGADGLMRASLSAVAPGTALRDGLERILRGNTGGLIVLGWDKTVESMCTGGFILDVEFTATRLR
ELCKLDGGIVIDKDITKILRAGVQLVPDPTIPTEETGTRHRTADRVSKQVSFPVVSVSQSMRLIALYVDGQRRVLEDSAA
ILSRANQALATLERYKLRLDEVAGTLSALEIEDLVTVRDVTAVAQRLEMVRRIATEIAEYVVELGTDGRLLALQLDELIA
GVEPERELVVRDYVPEPTAKRSRTVDEALFELDALTHAELLELSTVARALGYTGSPETLDSAISPRGFRLLAKVPRLPGA
IIDRLVEHFGGLQKLLAASVDDLQAVDGVGEARARSVREGLSRLAESSILERYV

Nucleotide


Download         Length: 1125 bp        

>NTDB_id=677483 OG574_RS22405 WP_100597752.1 4914011..4915135(+) (disA) [Streptomyces sp. NBC_01445]
GTGGCAGCCAACGACCGGGCAGCAGCTCCCGGCAAGTCCGGCGGGAGCTCCGGCGCCGATGGGCTGATGCGCGCCTCACT
GAGCGCCGTCGCGCCCGGTACGGCGCTGCGTGACGGCCTCGAGCGAATCCTCCGCGGCAACACCGGCGGACTCATCGTTC
TCGGCTGGGACAAGACCGTCGAGTCGATGTGTACCGGCGGTTTCATCCTGGACGTCGAGTTCACCGCGACGCGCCTGCGC
GAGCTGTGCAAGCTCGACGGCGGCATCGTCATCGACAAGGACATCACCAAGATCCTTCGGGCGGGCGTCCAGTTGGTGCC
GGACCCCACGATCCCCACGGAGGAGACGGGCACGCGGCACCGCACGGCGGACCGCGTGAGCAAGCAGGTCAGCTTCCCTG
TGGTCTCCGTGTCGCAGTCGATGCGGCTCATCGCCCTCTACGTGGACGGGCAGCGGCGCGTTCTCGAGGACTCGGCCGCG
ATTCTCTCCCGGGCGAATCAGGCGCTGGCGACTCTCGAGCGGTACAAGCTCCGCTTGGACGAGGTGGCCGGGACGCTCTC
CGCGCTCGAGATCGAGGATCTCGTTACCGTGCGCGATGTGACCGCGGTCGCTCAGCGGCTGGAGATGGTGCGGCGCATCG
CCACCGAGATCGCCGAGTACGTGGTGGAGCTCGGGACGGACGGGCGACTGCTCGCCCTTCAGCTCGACGAGTTGATCGCC
GGCGTCGAGCCCGAGCGGGAGCTCGTCGTTCGGGACTATGTGCCGGAGCCCACCGCCAAGCGCTCCCGGACCGTTGATGA
GGCGCTGTTCGAGCTCGATGCGCTGACGCATGCCGAGCTTCTTGAACTGTCCACTGTGGCACGCGCGTTGGGGTACACCG
GGTCTCCGGAGACCCTCGACTCGGCCATTTCGCCTCGCGGGTTCCGGCTGCTGGCGAAGGTGCCCCGGCTGCCTGGGGCG
ATCATTGACCGGCTTGTCGAGCACTTTGGCGGGTTGCAGAAGCTGCTCGCCGCCAGCGTCGATGATCTGCAGGCTGTGGA
CGGCGTCGGGGAGGCTCGTGCCCGGAGCGTGCGGGAAGGGCTCTCGCGGTTGGCCGAGTCTTCGATCCTTGAGCGGTACG
TCTAG

Domains

Predicted by InterProScan.

Helix-hairpin-helix motif (HHH_2)

(324-359)

DisA bacterial checkpoint controller nucleotide-binding (DAC)

(38-151)

DisA bacterial checkpoint controller linker region (DisA-linker)

(155-297)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  disA Bacillus subtilis subsp. subtilis str. 168

44.598

96.524

0.43