Detailed information
Bioinformatically predicted
Overview
| Name | ccrB | Type | Machinery gene |
| Locus tag | SAMI_RS00285 | Genome accession | NZ_AP017320 |
| Coordinates | 62397..64025 (-) | Length | 542 a.a. |
| NCBI ID | WP_001186602.1 | Uniprot ID | Q9XB94 |
| Organism | Staphylococcus aureus strain MI | ||
| Function | promote SCCmec transfer (predicted from homology) Homologous recombination |
||
Related MGE
Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.
Gene-MGE association summary
| MGE type | MGE coordinates | Gene coordinates | Relative position | Distance (bp) |
|---|---|---|---|---|
| ICE | 57176..100901 | 62397..64025 | within | 0 |
| SCCmec | 44031..65396 | 62397..64025 | within | 0 |
Gene organization within MGE regions
Location: 44031..100901
| Locus tag | Gene name | Coordinates (strand) | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| SAMI_RS00190 (SAMI_0037) | mecA | 44031..46040 (-) | 2010 | WP_001801873.1 | PBP2a family beta-lactam-resistant peptidoglycan transpeptidase MecA | - |
| SAMI_RS00195 (SAMI_0038) | mecR1 | 46137..47894 (+) | 1758 | WP_000952923.1 | beta-lactam sensor/signal transducer MecR1 | - |
| SAMI_RS00200 (SAMI_0039) | mecI | 47894..48265 (+) | 372 | WP_000369214.1 | mecA-type methicillin resistance repressor MecI | - |
| SAMI_RS15590 | psm-mec | 48350..48418 (-) | 69 | WP_014532405.1 | phenol-soluble modulin PSM-mec | - |
| SAMI_RS00205 (SAMI_0040) | - | 48752..49882 (+) | 1131 | WP_010922808.1 | ROK family transcriptional regulator | - |
| SAMI_RS00215 (SAMI_0042) | cstB | 49996..51330 (-) | 1335 | Protein_39 | persulfide dioxygenase-sulfurtransferase CstB | - |
| SAMI_RS00220 (SAMI_0043) | - | 51363..52427 (-) | 1065 | WP_000438836.1 | DsrE/DsrF/DrsH-like family protein | - |
| SAMI_RS00225 (SAMI_0044) | cstR | 52563..52823 (+) | 261 | WP_000220507.1 | persulfide-sensing transcriptional repressor CstR | - |
| SAMI_RS00230 | - | 52823..53461 (+) | 639 | Protein_42 | sulfite exporter TauE/SafE family protein | - |
| SAMI_RS00235 (SAMI_0046) | - | 53806..54468 (-) | 663 | WP_001092058.1 | class I SAM-dependent methyltransferase | - |
| SAMI_RS16010 | - | 54860..54919 (+) | 60 | WP_010959190.1 | erythromycin resistance leader peptide | - |
| SAMI_RS00240 (SAMI_0047) | erm(A) | 55002..55733 (+) | 732 | WP_001072201.1 | 23S rRNA (adenine(2058)-N(6))-methyltransferase Erm(A) | - |
| SAMI_RS00245 (SAMI_0048) | - | 55859..56641 (-) | 783 | WP_000067268.1 | aminoglycoside nucleotidyltransferase ANT(9)-Ia | - |
| SAMI_RS00250 (SAMI_0049) | - | 56792..57169 (-) | 378 | WP_000361059.1 | DUF6262 family protein | - |
| SAMI_RS00255 (SAMI_0050) | - | 57176..59068 (-) | 1893 | WP_001557544.1 | site-specific integrase | - |
| SAMI_RS00260 (SAMI_0051) | - | 59065..60150 (-) | 1086 | WP_000868132.1 | tyrosine-type recombinase/integrase | - |
| SAMI_RS00265 (SAMI_0052) | - | 60269..60586 (-) | 318 | WP_000659050.1 | JAB domain-containing protein | - |
| SAMI_RS00270 (SAMI_0053) | - | 60607..61113 (-) | 507 | WP_001092170.1 | DUF1643 domain-containing protein | - |
| SAMI_RS00275 (SAMI_0054) | - | 61131..61442 (-) | 312 | WP_000700853.1 | DUF960 family protein | - |
| SAMI_RS00280 (SAMI_0055) | - | 61529..61879 (-) | 351 | WP_000859155.1 | SAUGI family uracil-DNA glycosylase inhibitor | - |
| SAMI_RS00285 (SAMI_0056) | ccrB | 62397..64025 (-) | 1629 | WP_001186602.1 | cassette chromosome recombinase CcrB | Machinery gene |
| SAMI_RS00290 (SAMI_0057) | ccrA | 64047..65396 (-) | 1350 | WP_000815645.1 | cassette chromosome recombinase CcrA | Machinery gene |
| SAMI_RS00295 (SAMI_0058) | cch1 | 65630..67423 (-) | 1794 | WP_000195105.1 | cassette chromosome replicative helicase | - |
| SAMI_RS00300 (SAMI_0059) | ssb | 67423..67719 (-) | 297 | WP_000273824.1 | cassette chromosome ssDNA-binding protein | - |
| SAMI_RS00305 (SAMI_0060) | - | 67912..68958 (-) | 1047 | WP_001060125.1 | hypothetical protein | - |
| SAMI_RS14950 | - | 69209..70350 (-) | 1142 | Protein_59 | IS3-like element ISSau4 family transposase | - |
| SAMI_RS00320 | - | 70861..71796 (-) | 936 | Protein_60 | YfcC family protein | - |
| SAMI_RS00325 (SAMI_0067) | - | 72509..73204 (-) | 696 | WP_000858967.1 | response regulator transcription factor | - |
| SAMI_RS00330 (SAMI_0068) | - | 73179..75848 (-) | 2670 | WP_000446429.1 | sensor histidine kinase | - |
| SAMI_RS00335 | kdpF | 76015..76095 (+) | 81 | WP_000631574.1 | K(+)-transporting ATPase subunit F | - |
| SAMI_RS00340 (SAMI_0069) | kdpA | 76116..77792 (+) | 1677 | WP_000029430.1 | potassium-transporting ATPase subunit KdpA | - |
| SAMI_RS00345 (SAMI_0070) | - | 77811..79832 (+) | 2022 | WP_000852430.1 | K(+)-transporting ATPase subunit B | - |
| SAMI_RS00350 (SAMI_0071) | - | 79848..80405 (+) | 558 | WP_001193482.1 | K(+)-transporting ATPase subunit C | - |
| SAMI_RS00355 (SAMI_0072) | - | 80950..81819 (-) | 870 | WP_000626133.1 | hypothetical protein | - |
| SAMI_RS00360 (SAMI_0073) | - | 81829..82725 (-) | 897 | WP_000411461.1 | DUF927 domain-containing protein | - |
| SAMI_RS00370 (SAMI_0075) | - | 83844..84470 (-) | 627 | WP_001176969.1 | hypothetical protein | - |
| SAMI_RS00375 (SAMI_0076) | - | 84585..86093 (+) | 1509 | WP_001001347.1 | protein kinase domain-containing protein | - |
| SAMI_RS00380 | - | 86343..86477 (-) | 135 | WP_001790628.1 | hypothetical protein | - |
| SAMI_RS00385 | - | 86441..86533 (+) | 93 | WP_001790000.1 | hypothetical protein | - |
| SAMI_RS00390 (SAMI_0077) | - | 86680..88425 (+) | 1746 | WP_000700190.1 | DUF6119 family protein | - |
| SAMI_RS00395 (SAMI_0078) | - | 88523..88878 (-) | 356 | Protein_74 | tRNA-dihydrouridine synthase | - |
| SAMI_RS00400 | - | 89183..89271 (-) | 89 | Protein_75 | hypothetical protein | - |
| SAMI_RS00405 (SAMI_0079) | - | 89369..90124 (-) | 756 | WP_000355845.1 | sulfite exporter TauE/SafE family protein | - |
| SAMI_RS00410 (SAMI_0080) | cstR | 90124..90384 (-) | 261 | WP_001105088.1 | persulfide-sensing transcriptional repressor CstR | - |
| SAMI_RS00415 (SAMI_0081) | cstA | 90521..91585 (+) | 1065 | WP_000816133.1 | persulfide response sulfurtransferase CstA | - |
| SAMI_RS00420 (SAMI_0082) | cstB | 91616..92950 (+) | 1335 | WP_000465472.1 | persulfide dioxygenase-sulfurtransferase CstB | - |
| SAMI_RS00425 (SAMI_0083) | sqr | 92969..94162 (+) | 1194 | WP_001033018.1 | type II sulfide:quinone oxidoreductase Sqr | - |
| SAMI_RS15985 | - | 94429..94643 (-) | 215 | Protein_81 | universal stress protein | - |
| SAMI_RS00435 (SAMI_0084) | - | 94829..95815 (-) | 987 | WP_000662022.1 | tRNA dihydrouridine synthase | - |
| SAMI_RS00440 | - | 96124..96327 (+) | 204 | WP_000389759.1 | DUF6007 family protein | - |
| SAMI_RS00445 (SAMI_0085) | - | 96376..96672 (+) | 297 | WP_000201644.1 | TfoX/Sxy family protein | - |
| SAMI_RS00450 (SAMI_0086) | - | 96880..97482 (+) | 603 | WP_000908956.1 | hypothetical protein | - |
| SAMI_RS00455 (SAMI_0087) | - | 97749..100901 (+) | 3153 | WP_000080564.1 | DEAD/DEAH box helicase | - |
Sequence
Protein
Download Length: 542 a.a. Molecular weight: 62664.84 Da Isoelectric Point: 9.8600
>NTDB_id=67708 SAMI_RS00285 WP_001186602.1 62397..64025(-) (ccrB) [Staphylococcus aureus strain MI]
MQQLKTKRVGIYVRVSTEMQSTEGYSIDGQINQIKEYCDFHHFEVKDIYADRGISGKSMNRPELQRILKDAKEGYIDCVM
VYKTNRLARNTSDLLKIVEDLHKQNVEFFSLSERMEVNTSSGKLMLQILASFSEFERNNIVENVFMGQTRRAQEGYYQGN
LPLGYDKIPNSKHELMINQHEANIVKYIFESYAKGHGYRKIANALNHKGYVTKKGKPFSISSITYILANPFYIGKIQFAK
YKDWSEKRRKGLNDKPVIAEGKHSPIINQDLWDKVQMRKKQVSQKPQVHGKGTNLLTGIIHCPQCGAPMAASNTTNTLKD
GTKKRIRYYSCSNFRNKGSKVCSANSVRADVIEDYVMKQILEIVKSDKVIQRVVTHVNQENQVDGAALHHDIAYKQQQYD
EVQIKLNNLIKTIEDNPDLTSVIRPSIQKYEKQLNDITNQINQLKNQQNEDKPLFDAKEISKLLQHIFHDIKHIEKSRLK
ALYLSVIDRIDIKKDGNHKKQFYVTLKLNNEIIKQLFNNKQLDEVHLSTSSLFLPQTLYLTI
MQQLKTKRVGIYVRVSTEMQSTEGYSIDGQINQIKEYCDFHHFEVKDIYADRGISGKSMNRPELQRILKDAKEGYIDCVM
VYKTNRLARNTSDLLKIVEDLHKQNVEFFSLSERMEVNTSSGKLMLQILASFSEFERNNIVENVFMGQTRRAQEGYYQGN
LPLGYDKIPNSKHELMINQHEANIVKYIFESYAKGHGYRKIANALNHKGYVTKKGKPFSISSITYILANPFYIGKIQFAK
YKDWSEKRRKGLNDKPVIAEGKHSPIINQDLWDKVQMRKKQVSQKPQVHGKGTNLLTGIIHCPQCGAPMAASNTTNTLKD
GTKKRIRYYSCSNFRNKGSKVCSANSVRADVIEDYVMKQILEIVKSDKVIQRVVTHVNQENQVDGAALHHDIAYKQQQYD
EVQIKLNNLIKTIEDNPDLTSVIRPSIQKYEKQLNDITNQINQLKNQQNEDKPLFDAKEISKLLQHIFHDIKHIEKSRLK
ALYLSVIDRIDIKKDGNHKKQFYVTLKLNNEIIKQLFNNKQLDEVHLSTSSLFLPQTLYLTI
Nucleotide
Download Length: 1629 bp
>NTDB_id=67708 SAMI_RS00285 WP_001186602.1 62397..64025(-) (ccrB) [Staphylococcus aureus strain MI]
ATGCAACAACTTAAAACAAAACGTGTCGGTATCTATGTACGTGTATCAACAGAAATGCAAAGCACAGAAGGTTATAGTAT
CGACGGACAAATCAATCAAATCAAAGAATACTGTGACTTCCATCATTTTGAAGTTAAAGATATATACGCTGACCGTGGTA
TTTCAGGTAAATCTATGAATCGACCTGAGCTCCAACGTATATTGAAGGATGCGAAAGAAGGCTATATCGACTGTGTTATG
GTCTACAAAACAAACCGATTAGCTCGTAATACATCTGATCTTCTCAAAATTGTCGAAGATTTACACAAACAAAATGTCGA
ATTTTTCAGTTTATCAGAGCGTATGGAAGTCAATACTTCATCGGGTAAGCTCATGTTACAAATACTTGCGAGTTTCTCAG
AATTCGAACGTAATAACATTGTCGAGAATGTATTTATGGGTCAAACGAGACGTGCCCAAGAAGGCTATTATCAAGGCAAT
TTGCCGCTGGGCTATGACAAAATACCTAATAGTAAACATGAACTGATGATTAATCAACATGAAGCTAATATTGTGAAATA
TATATTCGAGTCCTATGCCAAAGGCCATGGCTATCGTAAAATAGCCAATGCATTAAATCACAAAGGCTATGTCACTAAAA
AGGGTAAACCTTTTAGTATTAGTTCTATCACATATATATTAGCTAACCCATTCTATATCGGCAAAATTCAATTTGCGAAA
TACAAAGATTGGAGTGAAAAACGTCGTAAAGGGCTTAATGATAAACCAGTGATAGCTGAAGGTAAGCATTCCCCCATTAT
TAATCAAGATTTATGGGATAAAGTACAAATGCGTAAAAAACAAGTCAGTCAAAAACCCCAAGTCCATGGCAAAGGAACGA
ATCTGCTTACAGGCATTATTCACTGTCCCCAATGTGGCGCACCTATGGCAGCAAGCAATACCACGAATACACTTAAAGAC
GGGACTAAGAAACGTATTCGTTACTATTCATGTAGTAATTTTCGGAACAAGGGTTCCAAAGTATGTTCGGCAAACAGTGT
AAGAGCTGATGTGATTGAAGATTATGTGATGAAGCAAATACTTGAAATAGTCAAAAGTGATAAAGTCATTCAACGCGTAG
TAACACACGTCAATCAAGAAAATCAAGTTGATGGCGCTGCACTTCATCACGATATTGCTTATAAGCAACAACAATATGAT
GAAGTACAAATCAAACTAAATAACTTGATTAAAACCATCGAGGATAATCCGGACTTAACATCAGTAATCAGACCAAGTAT
TCAAAAATATGAAAAGCAACTCAATGACATTACGAATCAAATCAACCAACTCAAAAATCAACAAAATGAAGATAAGCCTT
TATTTGATGCCAAAGAAATCAGTAAACTATTACAACACATCTTTCATGATATTAAGCACATAGAAAAATCTCGACTCAAA
GCATTGTATCTATCAGTGATTGATCGCATTGATATTAAAAAAGATGGTAATCATAAAAAACAATTCTATGTCACACTCAA
ACTTAATAACGAAATCATAAAACAACTTTTCAATAATAAACAACTCGACGAAGTGCATCTCAGCACTTCGTCTTTGTTTT
TGCCCCAAACACTATATCTTACTATTTAG
ATGCAACAACTTAAAACAAAACGTGTCGGTATCTATGTACGTGTATCAACAGAAATGCAAAGCACAGAAGGTTATAGTAT
CGACGGACAAATCAATCAAATCAAAGAATACTGTGACTTCCATCATTTTGAAGTTAAAGATATATACGCTGACCGTGGTA
TTTCAGGTAAATCTATGAATCGACCTGAGCTCCAACGTATATTGAAGGATGCGAAAGAAGGCTATATCGACTGTGTTATG
GTCTACAAAACAAACCGATTAGCTCGTAATACATCTGATCTTCTCAAAATTGTCGAAGATTTACACAAACAAAATGTCGA
ATTTTTCAGTTTATCAGAGCGTATGGAAGTCAATACTTCATCGGGTAAGCTCATGTTACAAATACTTGCGAGTTTCTCAG
AATTCGAACGTAATAACATTGTCGAGAATGTATTTATGGGTCAAACGAGACGTGCCCAAGAAGGCTATTATCAAGGCAAT
TTGCCGCTGGGCTATGACAAAATACCTAATAGTAAACATGAACTGATGATTAATCAACATGAAGCTAATATTGTGAAATA
TATATTCGAGTCCTATGCCAAAGGCCATGGCTATCGTAAAATAGCCAATGCATTAAATCACAAAGGCTATGTCACTAAAA
AGGGTAAACCTTTTAGTATTAGTTCTATCACATATATATTAGCTAACCCATTCTATATCGGCAAAATTCAATTTGCGAAA
TACAAAGATTGGAGTGAAAAACGTCGTAAAGGGCTTAATGATAAACCAGTGATAGCTGAAGGTAAGCATTCCCCCATTAT
TAATCAAGATTTATGGGATAAAGTACAAATGCGTAAAAAACAAGTCAGTCAAAAACCCCAAGTCCATGGCAAAGGAACGA
ATCTGCTTACAGGCATTATTCACTGTCCCCAATGTGGCGCACCTATGGCAGCAAGCAATACCACGAATACACTTAAAGAC
GGGACTAAGAAACGTATTCGTTACTATTCATGTAGTAATTTTCGGAACAAGGGTTCCAAAGTATGTTCGGCAAACAGTGT
AAGAGCTGATGTGATTGAAGATTATGTGATGAAGCAAATACTTGAAATAGTCAAAAGTGATAAAGTCATTCAACGCGTAG
TAACACACGTCAATCAAGAAAATCAAGTTGATGGCGCTGCACTTCATCACGATATTGCTTATAAGCAACAACAATATGAT
GAAGTACAAATCAAACTAAATAACTTGATTAAAACCATCGAGGATAATCCGGACTTAACATCAGTAATCAGACCAAGTAT
TCAAAAATATGAAAAGCAACTCAATGACATTACGAATCAAATCAACCAACTCAAAAATCAACAAAATGAAGATAAGCCTT
TATTTGATGCCAAAGAAATCAGTAAACTATTACAACACATCTTTCATGATATTAAGCACATAGAAAAATCTCGACTCAAA
GCATTGTATCTATCAGTGATTGATCGCATTGATATTAAAAAAGATGGTAATCATAAAAAACAATTCTATGTCACACTCAA
ACTTAATAACGAAATCATAAAACAACTTTTCAATAATAAACAACTCGACGAAGTGCATCTCAGCACTTCGTCTTTGTTTT
TGCCCCAAACACTATATCTTACTATTTAG
Similar proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|---|---|---|---|
| ccrB | Staphylococcus aureus N315 |
100 |
100 |
1 |