Detailed information NTG0675865

Bioinformatically predicted

Overview

• Name: disA
• Type: Machinery gene
• Locus tag: OG292_RS15880
• Genome accession: NZ_CP109417
• Coordinates: 3478528..3479661 (+)
• Length: 377 a.a.
• NCBI ID: WP_078075735.1
• Uniprot ID: A0A1U9QSN1
• Organism: Streptomyces sp. NBC_01511
• Function: homologous recombination (predicted from homology) Homologous recombination

Genomic Context

Location: 3473528..3484661

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
OG292_RS15865 (OG292_15840)	-	3474251..3475081 (+)	831	WP_405614078.1	hypothetical protein	-
OG292_RS15870 (OG292_15845)	-	3475122..3476915 (-)	1794	WP_405676208.1	BACON domain-containing protein	-
OG292_RS15875 (OG292_15850)	radA/sms	3477071..3478483 (+)	1413	WP_405614082.1	DNA repair protein RadA	Machinery gene
OG292_RS15880 (OG292_15855)	disA	3478528..3479661 (+)	1134	WP_078075735.1	DNA integrity scanning diadenylate cyclase DisA	Machinery gene
OG292_RS15885 (OG292_15860)	-	3479751..3480578 (-)	828	WP_405676209.1	hypothetical protein	-
OG292_RS15890 (OG292_15865)	-	3480760..3481365 (+)	606	Protein_3155	phosphatase PAP2 family protein	-
OG292_RS15895 (OG292_15870)	-	3481718..3482629 (+)	912	WP_405614087.1	A/G-specific adenine glycosylase	-
OG292_RS15900 (OG292_15875)	-	3482930..3483553 (+)	624	WP_405614089.1	SigE family RNA polymerase sigma factor	-
OG292_RS15905 (OG292_15880)	-	3483541..3484242 (+)	702	WP_405614091.1	hypothetical protein	-

Sequence

Protein

• Length: 377 a.a.
• Molecular weight: 40512.47 Da
• Isoelectric Point: 4.9406

>NTDB_id=675865 OG292_RS15880 WP_078075735.1 3478528..3479661(+) (disA) [Streptomyces sp. NBC_01511]
MAANDRAAAPGKSGGGSGGSGTEALMRASLSAVAPGMALRDGLERILRGNTGGLIVLGMDKTVETMCTGGFVLDVEFTAT
RLRELCKLDGALILDKDITKILRAGVQLVPDASIPTEETGTRHRTADRVSKQCGFPVISVSQSMRLIALYVDGERRVLEE
SAAILSRANQALATLERYKLRLDEVAGTLSALEIEDLVTVRDVTAVSQRLEMVRRIATEIAEYVVELGTDGRLLSLQLDE
LIAGVEPERELVVRDYVPEPTAKRSRTVAEAMTELDALSHTELLELPVVARALGYSGSPETLDSAVSPRGYRLLAKVPRL
PGAIIERLVEHFGGLQKLLAASVDDLQTVDGVGEARARSVREGLSRLAESSILERYV

Nucleotide

• Length: 1134 bp

>NTDB_id=675865 OG292_RS15880 WP_078075735.1 3478528..3479661(+) (disA) [Streptomyces sp. NBC_01511]
GTGGCAGCCAACGACCGGGCAGCAGCACCCGGAAAGTCCGGTGGTGGCTCCGGTGGATCCGGCACCGAAGCGCTGATGCG
CGCCTCACTGAGCGCCGTGGCGCCCGGTATGGCGCTGCGTGACGGCCTGGAGCGGATCCTCCGGGGGAACACCGGCGGTC
TCATCGTCCTGGGTATGGACAAGACCGTCGAAACGATGTGCACGGGCGGCTTCGTGCTGGACGTGGAGTTCACCGCGACG
CGGCTCCGCGAGCTGTGCAAGCTCGACGGCGCACTCATTCTCGACAAAGACATCACCAAGATTCTGCGGGCCGGTGTCCA
GCTCGTGCCCGACGCCTCCATCCCGACCGAGGAGACCGGCACCCGCCACCGCACGGCGGACCGGGTGTCCAAACAGTGCG
GGTTCCCGGTCATCTCCGTGTCGCAGTCGATGCGGCTGATCGCGCTGTACGTGGACGGGGAGCGCCGGGTCCTGGAGGAG
TCGGCGGCGATCCTGTCGCGCGCCAACCAGGCCCTGGCGACGCTGGAGCGCTACAAGCTCCGGCTGGACGAGGTCGCCGG
CACGCTCTCCGCGCTGGAGATCGAGGATCTGGTGACCGTCCGGGACGTGACGGCGGTCTCGCAGCGCCTGGAGATGGTGC
GCCGGATCGCCACGGAAATCGCCGAGTACGTGGTCGAGTTGGGCACCGACGGGCGGCTTCTCTCCCTCCAGCTCGACGAG
TTGATCGCGGGCGTCGAACCCGAGCGCGAGCTGGTCGTACGGGACTATGTGCCCGAGCCGACGGCGAAGCGGTCCCGTAC
GGTCGCCGAGGCGATGACCGAGCTGGACGCGCTCTCCCACACCGAGCTGCTGGAACTGCCCGTCGTGGCCCGCGCGTTGG
GCTACAGCGGCTCGCCCGAGACGCTGGACTCCGCGGTGTCGCCGCGCGGTTACCGGCTGCTGGCCAAGGTGCCGCGGCTG
CCGGGGGCGATCATCGAGCGGCTGGTCGAGCACTTCGGCGGACTCCAGAAGCTGCTGGCGGCGAGCGTCGACGACCTCCA
GACGGTGGACGGGGTCGGCGAGGCGCGGGCGCGCAGCGTGCGTGAGGGGCTGTCGCGGCTGGCGGAGTCGTCGATCCTGG
AGCGGTACGTCTGA

Domains

Predicted by InterProScan.

• DisA bacterial checkpoint controller linker region (DisA-linker) (158-300)

• Helix-hairpin-helix motif (HHH_2) (327-362)

• DisA bacterial checkpoint controller nucleotide-binding (DAC) (41-154)

3D structure

• AlphaFold DB: A0A1U9QSN1

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
disA	Bacillus subtilis subsp. subtilis str. 168	45.938	94.695	0.435