Detailed information NTG0675825

Bioinformatically predicted

Overview

• Name: sepM
• Type: Regulator
• Locus tag: MUY23_RS02325
• Genome accession: NZ_CP095162
• Coordinates: 474426..475475 (+)
• Length: 349 a.a.
• NCBI ID: WP_004194592.1
• Uniprot ID: A0A0N0DPM5
• Organism: Streptococcus suis strain TJS75
• Function: processing of CSP (predicted from homology) Competence regulation

Genomic Context

Location: 469426..480475

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
MUY23_RS02290	-	469747..470841 (+)	1095	WP_004194740.1	sensor histidine kinase	-
MUY23_RS02295	-	470838..471440 (+)	603	WP_004194738.1	response regulator transcription factor	-
MUY23_RS02300	-	471740..471958 (+)	219	WP_004194736.1	YqgQ family protein	-
MUY23_RS02305	-	471958..472344 (+)	387	WP_004194735.1	rhodanese-like domain-containing protein	-
MUY23_RS02310	-	472401..473123 (+)	723	WP_013730502.1	hypothetical protein	-
MUY23_RS02315	rsmD	473422..473961 (+)	540	WP_024394248.1	16S rRNA (guanine(966)-N(2))-methyltransferase RsmD	-
MUY23_RS02320	coaD	473951..474439 (+)	489	WP_002939048.1	pantetheine-phosphate adenylyltransferase	-
MUY23_RS02325	sepM	474426..475475 (+)	1050	WP_004194592.1	SepM family pheromone-processing serine protease	Regulator
MUY23_RS02330	-	475663..476304 (+)	642	WP_004194595.1	YutD-like domain-containing protein	-
MUY23_RS02335	rlmN	476313..477425 (+)	1113	WP_004194597.1	23S rRNA (adenine(2503)-C(2))-methyltransferase RlmN	-
MUY23_RS02340	-	477422..477949 (+)	528	WP_004194600.1	VanZ family protein	-
MUY23_RS02345	nadE	478823..479647 (-)	825	WP_004194617.1	ammonia-dependent NAD(+) synthetase	-

Sequence

Protein

• Length: 349 a.a.
• Molecular weight: 37747.80 Da
• Isoelectric Point: 4.6112

>NTDB_id=675825 MUY23_RS02325 WP_004194592.1 474426..475475(+) (sepM) [Streptococcus suis strain TJS75]
MKKNRKLTLIASIVLGTLLIWFAVFVRLPYYLESPGGAADIRQVLTVNNQIDQEDGSYNFTYVSVQQATALQLFAAQFDP
YTTVRSSEEMTGGADNEEYFRIARFYMETSQNMAKYQGLTLAGKEVNLDFFGVYVLALTDDSTFKKVLNIADTVVSINGK
TFESSPDLIKYVSGLEVGSDVTVGYISAGQEKSADGKIIKLSNGKNGIGITLVDHTEVQSSVPIDFQTGDIGGPSAGLMF
TLAIYTQLAEPDLRDGRIIAGTGTIEQDGKVGDIGGADKKVISAAKSGASIFFVPNNPVDVEVLKKNPKAKTNYEEAKEA
AEKAGLDIEVVPVKTVQEAIDYLKKTKGE

Nucleotide

• Length: 1050 bp

>NTDB_id=675825 MUY23_RS02325 WP_004194592.1 474426..475475(+) (sepM) [Streptococcus suis strain TJS75]
ATGAAGAAAAATAGGAAGTTAACCTTAATTGCATCTATTGTTTTAGGAACTCTTTTGATTTGGTTTGCCGTTTTTGTTCG
TCTGCCTTATTATCTGGAAAGTCCAGGTGGAGCTGCCGATATTCGTCAGGTACTAACGGTGAACAATCAAATAGACCAAG
AGGATGGCTCTTACAACTTCACCTATGTATCAGTCCAACAAGCTACAGCTTTACAACTATTCGCTGCTCAGTTTGATCCC
TATACGACAGTTCGTTCCTCTGAAGAGATGACAGGAGGGGCCGACAATGAGGAGTATTTCCGTATAGCACGGTTTTACAT
GGAAACTTCGCAAAATATGGCGAAGTATCAAGGATTGACCTTGGCAGGAAAAGAAGTCAATCTTGATTTCTTTGGTGTCT
ATGTGCTTGCCTTGACGGATGATTCAACCTTTAAAAAAGTTCTTAATATTGCCGACACTGTTGTGAGTATCAATGGAAAA
ACATTTGAGTCTTCTCCTGATTTGATTAAATATGTGAGTGGCTTGGAGGTTGGAAGTGATGTAACAGTTGGTTATATTAG
CGCTGGTCAGGAAAAATCTGCGGACGGTAAGATTATCAAATTATCTAATGGCAAAAACGGAATAGGCATCACTCTCGTAG
ACCATACAGAGGTTCAAAGTTCGGTTCCAATTGATTTCCAAACGGGAGATATTGGTGGTCCAAGTGCTGGTCTGATGTTT
ACACTTGCCATCTATACTCAACTCGCAGAGCCTGACTTACGTGATGGTCGAATTATTGCTGGTACGGGGACTATCGAGCA
GGATGGAAAAGTAGGTGACATTGGTGGGGCTGATAAGAAGGTTATTTCGGCAGCTAAGTCAGGTGCAAGTATTTTTTTTG
TACCAAACAATCCAGTTGATGTAGAAGTTTTGAAGAAAAACCCAAAGGCTAAAACGAACTATGAAGAAGCTAAGGAAGCA
GCCGAGAAAGCAGGTCTAGATATTGAGGTAGTTCCTGTGAAAACTGTTCAAGAGGCTATTGATTATTTGAAGAAAACGAA
GGGCGAGTAA

Domains

Predicted by InterproScan.

• PDZ domain (PDZ_2) (132-195)

• Lon protease (S16) C-terminal proteolytic domain (Lon_C) (232-315)

3D structure

• AlphaFold DB: A0A0N0DPM5

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
sepM	Streptococcus mutans UA159	60.807	99.427	0.605