Detailed information    

insolico Bioinformatically predicted

Overview

Name   agrA   Type   Regulator
Locus tag   MUA78_RS03885 Genome accession   NZ_CP095116
Coordinates   804749..805465 (-) Length   238 a.a.
NCBI ID   WP_000688492.1    Uniprot ID   A0A7U7IEW1
Organism   Staphylococcus aureus strain IVB6156     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 799749..810465
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  MUA78_RS03865 (MUA78_03865) - 800844..801794 (+) 951 WP_000790321.1 LacI family DNA-binding transcriptional regulator -
  MUA78_RS03870 (MUA78_03870) - 801943..803427 (+) 1485 WP_262515365.1 sucrose-6-phosphate hydrolase -
  MUA78_RS03875 (MUA78_03875) - 803424..804386 (+) 963 WP_262515366.1 carbohydrate kinase -
  MUA78_RS03880 (MUA78_03880) - 804570..804677 (-) 108 WP_001803734.1 hypothetical protein -
  MUA78_RS03885 (MUA78_03885) agrA 804749..805465 (-) 717 WP_000688492.1 quorum-sensing response regulator AgrA Regulator
  MUA78_RS03890 (MUA78_03890) agrC 805484..806776 (-) 1293 WP_000387816.1 quorum-sensing sensor histidine kinase AgrC -
  MUA78_RS03895 (MUA78_03895) agrD 806801..806941 (-) 141 WP_000735197.1 cyclic lactone autoinducer peptide AgrD -
  MUA78_RS03900 (MUA78_03900) - 806945..807508 (-) 564 WP_001105710.1 accessory gene regulator AgrB -
  MUA78_RS14715 (MUA78_03905) hld 807798..807878 (+) 81 WP_000046022.1 delta-hemolysin -
  MUA78_RS03910 (MUA78_03910) - 808478..809263 (-) 786 WP_000867945.1 carbon-nitrogen family hydrolase -
  MUA78_RS03915 (MUA78_03915) - 809624..810250 (-) 627 WP_250406516.1 nitroreductase family protein -

Sequence

Protein


Download         Length: 238 a.a.        Molecular weight: 27905.90 Da        Isoelectric Point: 6.0927

>NTDB_id=675559 MUA78_RS03885 WP_000688492.1 804749..805465(-) (agrA) [Staphylococcus aureus strain IVB6156]
MKIFICEDDPKQRENMVTIIKNYIMIEEKPMEIALATDNPYEVLEQAKNMNDIGCYFLDIQLSTDINGIKLGSEIRKHDP
VGNIIFVTSHSELTYLTFVYKVAAMDFIFKDDPAELRTRIIDCLETAHTRLQLLSKDNSVETIELKRGSNSVYVQYDDIM
FFESSTKSHRLIAHLDNRQIEFYGNLKELSQLDDRFFRCHNSFVVNRHNIESIDSKERIVYFKNKEHCYASVRNVKKI

Nucleotide


Download         Length: 717 bp        

>NTDB_id=675559 MUA78_RS03885 WP_000688492.1 804749..805465(-) (agrA) [Staphylococcus aureus strain IVB6156]
ATGAAAATTTTCATTTGCGAAGACGATCCAAAACAAAGAGAAAACATGGTTACCATTATTAAAAATTATATAATGATAGA
AGAAAAGCCTATGGAAATTGCCCTCGCAACTGATAATCCTTATGAGGTGCTTGAGCAAGCTAAAAATATGAATGACATAG
GCTGTTACTTTTTAGATATTCAACTTTCAACTGATATTAATGGTATCAAATTAGGCAGTGAAATTCGTAAGCATGATCCA
GTTGGTAACATTATATTTGTTACGAGTCACAGTGAACTTACCTATTTAACGTTTGTCTACAAAGTTGCAGCGATGGACTT
TATTTTTAAAGATGATCCAGCTGAATTAAGAACTCGAATTATAGACTGTTTAGAAACTGCACATACACGCTTACAATTGT
TGTCTAAAGATAATAGCGTTGAAACGATTGAATTAAAACGTGGCAGTAATTCAGTGTATGTTCAATATGATGATATTATG
TTTTTTGAATCATCAACAAAATCTCACAGACTCATTGCCCATTTAGATAACCGCCAAATTGAATTTTATGGTAATTTAAA
AGAACTGAGTCAATTAGATGATCGTTTCTTTAGATGTCATAATAGCTTTGTCGTCAATCGCCATAATATTGAATCTATAG
ATTCGAAAGAGCGAATTGTCTATTTTAAAAATAAAGAACACTGCTATGCATCGGTGAGAAACGTTAAAAAAATATAA

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(3-120)

LytTr DNA-binding domain (LytTR)

(151-237)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A7U7IEW1

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  agrA Staphylococcus aureus N315

100

100

1