Detailed information NTG0675484

Bioinformatically predicted

Overview

• Name: vraS
• Type: Regulator
• Locus tag: MUA63_RS04920
• Genome accession: NZ_CP095107
• Coordinates: 1038411..1039454 (+)
• Length: 347 a.a.
• NCBI ID: WP_019166463.1
• Uniprot ID: A0A2A4GVQ0
• Organism: Staphylococcus delphini strain IVB6226
• Function: repress expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 1033411..1044454

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
MUA63_RS04895 (MUA63_04885)	-	1033551..1034273 (+)	723	WP_262611974.1	type 1 glutamine amidotransferase	-
MUA63_RS04900 (MUA63_04890)	-	1035357..1036355 (-)	999	WP_262611975.1	aromatic acid exporter family protein	-
MUA63_RS04905 (MUA63_04895)	map	1036452..1037213 (+)	762	WP_019166460.1	type I methionyl aminopeptidase	-
MUA63_RS04910 (MUA63_04900)	-	1037311..1037700 (+)	390	WP_262611976.1	hypothetical protein	-
MUA63_RS04915 (MUA63_04905)	liaF	1037713..1038414 (+)	702	WP_096597675.1	cell wall-active antibiotics response protein LiaF	-
MUA63_RS04920 (MUA63_04910)	vraS	1038411..1039454 (+)	1044	WP_019166463.1	sensor histidine kinase	Regulator
MUA63_RS04925 (MUA63_04915)	vraR	1039444..1040073 (+)	630	WP_262611977.1	response regulator transcription factor	Regulator
MUA63_RS04930 (MUA63_04920)	-	1040708..1041289 (-)	582	WP_262611978.1	carbonic anhydrase	-
MUA63_RS04935 (MUA63_04925)	-	1041322..1042668 (-)	1347	WP_262611979.1	YihY/virulence factor BrkB family protein	-
MUA63_RS04940 (MUA63_04930)	-	1042884..1043171 (-)	288	WP_014613485.1	YtxH domain-containing protein	-
MUA63_RS04945 (MUA63_04935)	-	1043179..1043637 (-)	459	WP_262611980.1	low molecular weight protein-tyrosine-phosphatase	-
MUA63_RS04950 (MUA63_04940)	-	1043771..1043974 (+)	204	WP_019169369.1	DUF1128 family protein	-

Sequence

Protein

• Length: 347 a.a.
• Molecular weight: 39911.18 Da
• Isoelectric Point: 5.0397

>NTDB_id=675484 MUA63_RS04920 WP_019166463.1 1038411..1039454(+) (vraS) [Staphylococcus delphini strain IVB6226]
MNHYVRAIGSMLILVYSMLTAFFFIDKVFTNIIFFQGMFYTQILGIPVFIFLNLVVIFLCIIVGSVLAYKINQQNDWVKQ
QIVRAFEGETVGINDQQLELYNETIELYQALVPLNQELHKMRIKTQNLTNETYNLNDLKVKKIIEDERQRLARELHDSVS
QQLFAASMMLSAIKETDLAPPLDQQIPTLEKMVQDSQLEMRALLLHLRPIGLKDKSLGEGIKSLVTDLQRKVPIKVVQEI
DEFEVPKGIEDHLFRITQEAISNTLRHAEGTQVTVELLNRNDYLLLRIQDDGIGFNVDDKLEQSYGLKNMRERAIEIGAT
FHIVSLPDAGTRIEVKAPLEKEEQHDN

Nucleotide

• Length: 1044 bp

>NTDB_id=675484 MUA63_RS04920 WP_019166463.1 1038411..1039454(+) (vraS) [Staphylococcus delphini strain IVB6226]
ATGAATCACTACGTCCGAGCGATAGGTTCGATGCTCATTCTCGTATATAGTATGCTCACCGCGTTTTTCTTTATCGATAA
AGTGTTTACCAATATTATTTTCTTTCAAGGCATGTTTTATACACAAATTTTAGGGATTCCTGTTTTTATCTTTTTAAATT
TAGTCGTCATTTTTTTATGTATTATCGTGGGCAGTGTGTTAGCTTATAAAATCAATCAACAAAATGATTGGGTGAAGCAA
CAAATCGTTCGTGCTTTCGAAGGCGAAACAGTGGGAATCAATGATCAACAACTTGAGCTGTATAATGAAACGATTGAATT
GTACCAAGCGCTCGTCCCATTGAATCAAGAACTGCATAAAATGCGGATTAAAACACAAAATTTAACGAATGAAACGTATA
ATTTAAATGATTTGAAGGTGAAAAAGATTATAGAAGATGAACGGCAGCGTTTAGCACGAGAATTGCATGATAGTGTGTCG
CAACAACTTTTCGCGGCAAGTATGATGTTGTCTGCAATCAAGGAAACAGATTTAGCTCCACCGTTAGACCAACAAATTCC
AACGTTAGAAAAAATGGTGCAAGACTCACAACTTGAAATGCGTGCACTGTTACTTCATTTAAGACCTATAGGATTGAAGG
ATAAATCGTTAGGTGAGGGGATAAAATCGCTCGTGACGGATTTACAACGCAAAGTGCCCATTAAAGTCGTGCAAGAAATT
GATGAGTTTGAAGTCCCTAAAGGTATTGAGGATCACCTTTTTAGGATTACCCAAGAAGCGATTTCCAATACGTTACGACA
TGCTGAGGGAACGCAAGTAACAGTAGAATTACTTAACCGCAATGATTATTTATTGTTGCGTATACAAGATGACGGCATTG
GATTTAATGTCGATGATAAATTAGAACAAAGTTATGGATTAAAAAATATGCGTGAACGTGCAATAGAGATTGGTGCCACG
TTTCATATCGTCTCATTACCTGATGCAGGGACGAGAATAGAAGTGAAAGCACCACTTGAAAAGGAGGAACAGCATGACAA
TTAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (249-341)

• Histidine kinase (HisKA_3) (147-210)

3D structure

• AlphaFold DB: A0A2A4GVQ0

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vraS	Staphylococcus aureus N315	83.573	100	0.836