Detailed information
Bioinformatically predicted
Overview
| Name | ccrA | Type | Machinery gene |
| Locus tag | MUA63_RS00380 | Genome accession | NZ_CP095107 |
| Coordinates | 78899..80248 (-) | Length | 449 a.a. |
| NCBI ID | WP_262611009.1 | Uniprot ID | - |
| Organism | Staphylococcus delphini strain IVB6226 | ||
| Function | promote SCCmec transfer (predicted from homology) Homologous recombination |
||
Related MGE
Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.
Gene-MGE association summary
| MGE type | MGE coordinates | Gene coordinates | Relative position | Distance (bp) |
|---|---|---|---|---|
| Prophage | 77249..125294 | 78899..80248 | within | 0 |
Gene organization within MGE regions
Location: 77249..125294
| Locus tag | Gene name | Coordinates (strand) | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| MUA63_RS00375 (MUA63_00375) | ccrB | 77249..78877 (-) | 1629 | Protein_72 | cassette chromosome recombinase CcrB | - |
| MUA63_RS00380 (MUA63_00380) | ccrA | 78899..80248 (-) | 1350 | WP_262611009.1 | cassette chromosome recombinase CcrA | Machinery gene |
| MUA63_RS00385 (MUA63_00385) | cch1 | 80427..82211 (-) | 1785 | WP_262619930.1 | cassette chromosome replicative helicase | - |
| MUA63_RS00390 (MUA63_00390) | ssb | 82211..82501 (-) | 291 | WP_107377044.1 | cassette chromosome ssDNA-binding protein | - |
| MUA63_RS00395 (MUA63_00395) | - | 82643..83743 (+) | 1101 | WP_262611015.1 | hypothetical protein | - |
| MUA63_RS00400 (MUA63_00400) | - | 83771..84445 (-) | 675 | WP_262619931.1 | IS6 family transposase | - |
| MUA63_RS00405 (MUA63_00405) | - | 84500..84691 (-) | 192 | Protein_78 | protein rep | - |
| MUA63_RS00410 (MUA63_00410) | - | 85190..85486 (+) | 297 | WP_096608588.1 | hypothetical protein | - |
| MUA63_RS00415 (MUA63_00415) | - | 86276..86476 (+) | 201 | WP_262611019.1 | hypothetical protein | - |
| MUA63_RS00420 (MUA63_00420) | - | 86623..87273 (-) | 651 | Protein_81 | protein rep | - |
| MUA63_RS00425 (MUA63_00425) | - | 87334..88008 (-) | 675 | WP_118003383.1 | IS6 family transposase | - |
| MUA63_RS00430 (MUA63_00430) | - | 88257..88616 (+) | 360 | WP_262619932.1 | abortive infection system antitoxin AbiGi family protein | - |
| MUA63_RS00435 (MUA63_00435) | - | 88997..89851 (+) | 855 | WP_394371805.1 | IS3 family transposase | - |
| MUA63_RS00440 (MUA63_00440) | - | 89956..90813 (+) | 858 | WP_142019173.1 | RhaT/GlcU family sugar-proton symporter | - |
| MUA63_RS00445 (MUA63_00445) | - | 90873..91664 (+) | 792 | WP_262619933.1 | glucose 1-dehydrogenase | - |
| MUA63_RS00450 (MUA63_00450) | - | 91880..92788 (-) | 909 | WP_262611025.1 | AEC family transporter | - |
| MUA63_RS00455 (MUA63_00455) | - | 92889..93599 (-) | 711 | WP_262611026.1 | site-specific DNA-methyltransferase | - |
| MUA63_RS00460 (MUA63_00460) | istB | 94069..94782 (-) | 714 | WP_262611028.1 | IS21-like element helper ATPase IstB | - |
| MUA63_RS00465 (MUA63_00465) | istA | 94848..96044 (-) | 1197 | WP_262619934.1 | IS21 family transposase | - |
| MUA63_RS00470 (MUA63_00470) | - | 96406..97074 (+) | 669 | WP_262611033.1 | Wzz/FepE/Etk N-terminal domain-containing protein | - |
| MUA63_RS00475 (MUA63_00475) | - | 97089..97778 (+) | 690 | WP_262611034.1 | polysaccharide biosynthesis tyrosine autokinase | - |
| MUA63_RS00480 (MUA63_00480) | - | 97775..98539 (+) | 765 | WP_262611035.1 | tyrosine-protein phosphatase | - |
| MUA63_RS00485 (MUA63_00485) | - | 98593..100380 (+) | 1788 | WP_394371806.1 | polysaccharide biosynthesis protein | - |
| MUA63_RS00490 (MUA63_00490) | - | 100394..101623 (+) | 1230 | WP_262611037.1 | asparagine synthase C-terminal domain-containing protein | - |
| MUA63_RS00495 (MUA63_00495) | - | 101616..102857 (+) | 1242 | WP_262611039.1 | lipopolysaccharide biosynthesis protein | - |
| MUA63_RS00500 (MUA63_00500) | - | 102859..104214 (+) | 1356 | WP_262611041.1 | O-antigen polymerase | - |
| MUA63_RS00505 (MUA63_00505) | - | 104215..105312 (+) | 1098 | WP_262611044.1 | glycosyltransferase | - |
| MUA63_RS00510 (MUA63_00510) | - | 105487..106503 (+) | 1017 | WP_316960077.1 | NAD-dependent epimerase | - |
| MUA63_RS00515 (MUA63_00515) | - | 106500..107636 (+) | 1137 | WP_262611046.1 | glycosyltransferase | - |
| MUA63_RS00520 (MUA63_00520) | - | 107640..108914 (+) | 1275 | WP_262619935.1 | nucleotide sugar dehydrogenase | - |
| MUA63_RS00525 (MUA63_00525) | - | 108961..110097 (+) | 1137 | WP_262611050.1 | glycosyltransferase family 4 protein | - |
| MUA63_RS00530 (MUA63_00530) | - | 110143..110700 (+) | 558 | WP_262611052.1 | sugar transferase | - |
| MUA63_RS00535 (MUA63_00535) | - | 110700..111584 (+) | 885 | WP_262611053.1 | NAD-dependent epimerase/dehydratase family protein | - |
| MUA63_RS00540 (MUA63_00540) | istA | 111840..113036 (+) | 1197 | WP_262619934.1 | IS21 family transposase | - |
| MUA63_RS00545 (MUA63_00545) | istB | 113102..113815 (+) | 714 | WP_262611028.1 | IS21-like element helper ATPase IstB | - |
| MUA63_RS00550 (MUA63_00550) | - | 114335..115293 (+) | 959 | Protein_107 | M23 family metallopeptidase | - |
| MUA63_RS00555 (MUA63_00555) | hypR | 115408..115842 (+) | 435 | WP_262611055.1 | redox-sensitive transcriptional regulator HypR | - |
| MUA63_RS00560 (MUA63_00560) | merA | 115829..117151 (+) | 1323 | WP_262619936.1 | hypothiocyanous acid reductase MerA | - |
| MUA63_RS00565 (MUA63_00565) | - | 117331..117645 (+) | 315 | WP_037576813.1 | metalloregulator ArsR/SmtB family transcription factor | - |
| MUA63_RS00570 (MUA63_00570) | arsB | 117642..118933 (+) | 1292 | Protein_111 | arsenite efflux transporter membrane subunit ArsB | - |
| MUA63_RS00575 (MUA63_00575) | arsC | 118951..119400 (+) | 450 | WP_262611059.1 | arsenate reductase (thioredoxin) | - |
| MUA63_RS00580 (MUA63_00580) | - | 119591..120790 (+) | 1200 | WP_316960082.1 | IS110 family transposase | - |
| MUA63_RS00585 (MUA63_00585) | - | 120981..121265 (-) | 285 | WP_262611061.1 | hypothetical protein | - |
| MUA63_RS00590 (MUA63_00590) | - | 121847..122512 (+) | 666 | WP_262611063.1 | Wzz/FepE/Etk N-terminal domain-containing protein | - |
| MUA63_RS00595 (MUA63_00595) | - | 122527..123198 (+) | 672 | WP_262611065.1 | CpsD/CapB family tyrosine-protein kinase | - |
| MUA63_RS00600 (MUA63_00600) | - | 123213..123977 (+) | 765 | WP_262611067.1 | tyrosine-protein phosphatase | - |
| MUA63_RS00605 (MUA63_00605) | - | 124001..124369 (+) | 369 | Protein_118 | hypothetical protein | - |
Sequence
Protein
Download Length: 449 a.a. Molecular weight: 52268.25 Da Isoelectric Point: 10.0277
>NTDB_id=675480 MUA63_RS00380 WP_262611009.1 78899..80248(-) (ccrA) [Staphylococcus delphini strain IVB6226]
MKQAIGYLRQSTTKQQSLTAQKQTIETLAKKYNIQHIIFYSDKQSGRTDNRTGYQQVIESIQQRQCDVLCCYRLNRLHRN
LKNALKLMKLCQKYHVHILSIHDGYFDMDKAFDRLKLNIFISLAELESDNIGEQVKNGLKEKARQGKLITTHAPFGYTYR
NGTFTINQDEAPTVKAIFHYYLQGYGYKKIAQYLEEDTKLINRKPYQVRAIIMNPNYCGRVINQYGQYDNMVPSIVSISI
YEQAQAIRAQKHTKRTPSSNQLKQKIKCPCCGSTLTNMTIRKKNHTLRYYVCPQNLNASRFICDFKGINAENLEKQVLES
CQKFFRDQQLYSKIKHAIEKQLKKQKMHNTNNTLTHEKLIEKLAQGTIDVETFREQSQSISLQHKPIQPISDIRIKASLQ
KVIQKSFTLKMLYPYIDEIHITKNKELSGIYLKDEPLNIVNQTIQSSTG
MKQAIGYLRQSTTKQQSLTAQKQTIETLAKKYNIQHIIFYSDKQSGRTDNRTGYQQVIESIQQRQCDVLCCYRLNRLHRN
LKNALKLMKLCQKYHVHILSIHDGYFDMDKAFDRLKLNIFISLAELESDNIGEQVKNGLKEKARQGKLITTHAPFGYTYR
NGTFTINQDEAPTVKAIFHYYLQGYGYKKIAQYLEEDTKLINRKPYQVRAIIMNPNYCGRVINQYGQYDNMVPSIVSISI
YEQAQAIRAQKHTKRTPSSNQLKQKIKCPCCGSTLTNMTIRKKNHTLRYYVCPQNLNASRFICDFKGINAENLEKQVLES
CQKFFRDQQLYSKIKHAIEKQLKKQKMHNTNNTLTHEKLIEKLAQGTIDVETFREQSQSISLQHKPIQPISDIRIKASLQ
KVIQKSFTLKMLYPYIDEIHITKNKELSGIYLKDEPLNIVNQTIQSSTG
Nucleotide
Download Length: 1350 bp
>NTDB_id=675480 MUA63_RS00380 WP_262611009.1 78899..80248(-) (ccrA) [Staphylococcus delphini strain IVB6226]
ATGAAACAAGCTATTGGTTATTTACGCCAAAGTACAACCAAGCAACAATCACTCACCGCACAGAAACAAACTATCGAAAC
GCTCGCTAAAAAATACAATATCCAACACATCATCTTTTATAGTGATAAGCAATCAGGCAGAACGGATAATCGAACTGGCT
ATCAACAAGTCATCGAAAGCATTCAACAAAGACAATGTGACGTATTATGTTGTTATCGCTTGAATCGACTGCATCGTAAT
TTGAAAAATGCATTAAAACTTATGAAACTGTGTCAAAAGTATCATGTTCATATTCTAAGTATTCATGATGGCTATTTTGA
TATGGATAAAGCGTTTGATCGCCTAAAACTTAATATATTCATAAGTCTCGCAGAATTAGAGTCCGATAATATTGGTGAAC
AAGTCAAGAATGGTCTTAAAGAAAAAGCTAGACAAGGTAAACTCATCACGACACATGCACCATTTGGTTATACCTATCGC
AATGGCACATTCACAATTAATCAAGATGAAGCACCAACGGTAAAGGCAATATTCCATTACTACCTACAAGGCTATGGTTA
TAAGAAAATTGCGCAATACTTAGAAGAAGATACTAAGCTAATCAACCGAAAACCCTATCAAGTACGCGCTATTATCATGA
ATCCTAATTATTGTGGTCGCGTTATCAATCAATATGGACAATATGACAATATGGTTCCATCTATTGTTTCGATCAGTATA
TACGAACAAGCTCAAGCAATACGGGCACAAAAACATACCAAACGGACTCCATCATCTAATCAACTCAAACAAAAAATCAA
ATGTCCGTGTTGTGGCTCAACACTCACAAATATGACAATTAGAAAAAAGAACCATACATTACGTTATTACGTCTGTCCTC
AAAATTTGAATGCATCACGTTTCATATGTGACTTTAAAGGAATAAACGCTGAAAACCTAGAAAAACAGGTCTTAGAATCC
TGCCAAAAATTCTTTCGAGACCAACAGCTCTATTCGAAAATCAAACACGCTATTGAGAAACAGCTCAAAAAACAAAAAAT
GCATAATACTAATAACACATTAACTCATGAAAAGCTCATTGAAAAATTAGCACAAGGAACAATTGATGTAGAAACATTCA
GAGAACAATCTCAATCAATAAGCCTGCAGCATAAACCTATACAACCAATAAGTGATATTCGGATAAAAGCATCACTACAA
AAGGTTATACAGAAAAGTTTCACGTTAAAAATGCTGTATCCATATATTGATGAAATTCATATTACTAAAAATAAAGAACT
AAGCGGCATCTATTTAAAAGATGAGCCACTAAACATCGTTAATCAAACGATACAATCATCAACTGGCTAA
ATGAAACAAGCTATTGGTTATTTACGCCAAAGTACAACCAAGCAACAATCACTCACCGCACAGAAACAAACTATCGAAAC
GCTCGCTAAAAAATACAATATCCAACACATCATCTTTTATAGTGATAAGCAATCAGGCAGAACGGATAATCGAACTGGCT
ATCAACAAGTCATCGAAAGCATTCAACAAAGACAATGTGACGTATTATGTTGTTATCGCTTGAATCGACTGCATCGTAAT
TTGAAAAATGCATTAAAACTTATGAAACTGTGTCAAAAGTATCATGTTCATATTCTAAGTATTCATGATGGCTATTTTGA
TATGGATAAAGCGTTTGATCGCCTAAAACTTAATATATTCATAAGTCTCGCAGAATTAGAGTCCGATAATATTGGTGAAC
AAGTCAAGAATGGTCTTAAAGAAAAAGCTAGACAAGGTAAACTCATCACGACACATGCACCATTTGGTTATACCTATCGC
AATGGCACATTCACAATTAATCAAGATGAAGCACCAACGGTAAAGGCAATATTCCATTACTACCTACAAGGCTATGGTTA
TAAGAAAATTGCGCAATACTTAGAAGAAGATACTAAGCTAATCAACCGAAAACCCTATCAAGTACGCGCTATTATCATGA
ATCCTAATTATTGTGGTCGCGTTATCAATCAATATGGACAATATGACAATATGGTTCCATCTATTGTTTCGATCAGTATA
TACGAACAAGCTCAAGCAATACGGGCACAAAAACATACCAAACGGACTCCATCATCTAATCAACTCAAACAAAAAATCAA
ATGTCCGTGTTGTGGCTCAACACTCACAAATATGACAATTAGAAAAAAGAACCATACATTACGTTATTACGTCTGTCCTC
AAAATTTGAATGCATCACGTTTCATATGTGACTTTAAAGGAATAAACGCTGAAAACCTAGAAAAACAGGTCTTAGAATCC
TGCCAAAAATTCTTTCGAGACCAACAGCTCTATTCGAAAATCAAACACGCTATTGAGAAACAGCTCAAAAAACAAAAAAT
GCATAATACTAATAACACATTAACTCATGAAAAGCTCATTGAAAAATTAGCACAAGGAACAATTGATGTAGAAACATTCA
GAGAACAATCTCAATCAATAAGCCTGCAGCATAAACCTATACAACCAATAAGTGATATTCGGATAAAAGCATCACTACAA
AAGGTTATACAGAAAAGTTTCACGTTAAAAATGCTGTATCCATATATTGATGAAATTCATATTACTAAAAATAAAGAACT
AAGCGGCATCTATTTAAAAGATGAGCCACTAAACATCGTTAATCAAACGATACAATCATCAACTGGCTAA
3D structure
| Source | ID | Structure |
|---|
Similar proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|---|---|---|---|
| ccrA | Staphylococcus aureus COL |
77.181 |
99.555 |
0.768 |
| ccrA | Staphylococcus aureus N315 |
71.938 |
100 |
0.719 |