Detailed information    

insolico Bioinformatically predicted

Overview

Name   agrA   Type   Regulator
Locus tag   MUA12_RS09030 Genome accession   NZ_CP095104
Coordinates   1764617..1765333 (+) Length   238 a.a.
NCBI ID   WP_002481723.1    Uniprot ID   -
Organism   Staphylococcus simulans strain IVB6179     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 1759617..1770333
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  MUA12_RS09005 (MUA12_08960) - 1760977..1761777 (+) 801 WP_107548250.1 carbon-nitrogen family hydrolase -
  MUA12_RS09010 (MUA12_08965) - 1762082..1762246 (-) 165 WP_262577134.1 delta-lysin family phenol-soluble modulin -
  MUA12_RS09015 (MUA12_08970) - 1762558..1763136 (+) 579 WP_262577136.1 accessory gene regulator AgrB -
  MUA12_RS09020 (MUA12_08975) agrD 1763136..1763273 (+) 138 WP_023015908.1 cyclic lactone autoinducer peptide AgrD -
  MUA12_RS09025 (MUA12_08980) agrC 1763313..1764614 (+) 1302 WP_262577138.1 quorum-sensing sensor histidine kinase AgrC -
  MUA12_RS09030 (MUA12_08985) agrA 1764617..1765333 (+) 717 WP_002481723.1 quorum-sensing response regulator AgrA Regulator
  MUA12_RS09035 (MUA12_08990) - 1765408..1766892 (-) 1485 WP_262577139.1 glycoside hydrolase family 32 protein -
  MUA12_RS09040 (MUA12_08995) - 1767128..1768216 (+) 1089 WP_262577140.1 YeeE/YedE family protein -
  MUA12_RS09045 (MUA12_09000) - 1768272..1768496 (+) 225 WP_002481726.1 sulfurtransferase TusA family protein -
  MUA12_RS09050 (MUA12_09005) ltrA 1768573..1769859 (-) 1287 WP_037556158.1 group II intron reverse transcriptase/maturase -

Sequence

Protein


Download         Length: 238 a.a.        Molecular weight: 27762.55 Da        Isoelectric Point: 4.6392

>NTDB_id=675473 MUA12_RS09030 WP_002481723.1 1764617..1765333(+) (agrA) [Staphylococcus simulans strain IVB6179]
MKIIICEDDVQQREHIESIIENYIMIEEKPLEVALSTGDPYEVLEFAKATNEICCYFLDIQLDSDINGIKLGSELRNYDS
VGSIIFITSHSELTYLTFVYKVAAMDFIFKDDPSEMKSRIIDCIETALTRLQLLSKESSLETIELKRGSNSVYVNYDDVM
FFESSAKSHRLIAHLDNRQIEFYGNLKDLSQLDDRFFRCHNSYVINRNNIEEVISKEREVYFKNGEHCYISVRNLKKI

Nucleotide


Download         Length: 717 bp        

>NTDB_id=675473 MUA12_RS09030 WP_002481723.1 1764617..1765333(+) (agrA) [Staphylococcus simulans strain IVB6179]
GTGAAGATTATTATATGCGAAGATGATGTACAACAGCGTGAACACATTGAATCCATCATTGAAAATTATATTATGATTGA
AGAAAAACCTTTAGAAGTGGCGCTCTCAACGGGTGATCCTTATGAGGTATTAGAATTCGCTAAAGCTACAAATGAGATTT
GTTGTTACTTCTTAGATATTCAGTTAGATTCTGATATTAACGGTATTAAGCTTGGCAGCGAACTTAGAAACTATGATTCT
GTCGGCAGTATTATCTTTATTACTAGTCACAGTGAACTCACTTATCTTACTTTCGTTTATAAAGTAGCAGCCATGGACTT
TATTTTTAAAGATGACCCTTCAGAAATGAAATCTCGAATTATTGATTGTATCGAAACTGCATTGACGAGACTACAGTTGC
TTTCAAAAGAATCTAGTCTCGAAACAATTGAGTTAAAACGTGGTAGTAACTCAGTCTATGTTAATTACGATGATGTCATG
TTCTTTGAATCCTCGGCAAAATCACATCGCTTAATTGCGCATTTAGACAATCGTCAAATCGAATTTTATGGCAACTTAAA
AGATTTAAGCCAATTAGATGACCGCTTCTTCCGTTGTCACAATAGTTACGTCATTAATCGCAATAACATCGAAGAAGTAA
TATCTAAAGAACGTGAGGTCTACTTTAAAAATGGTGAACACTGTTATATCTCAGTAAGAAATTTAAAGAAAATCTAA

Domains

Predicted by InterProScan.

LytTr DNA-binding domain (LytTR)

(151-237)

Response regulator receiver domain (Response_reg)

(3-120)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  agrA Staphylococcus aureus N315

79.412

100

0.794