Detailed information NTG0675397

Bioinformatically predicted

Overview

• Name: vraS
• Type: Regulator
• Locus tag: MUA87_RS04845
• Genome accession: NZ_CP095100
• Coordinates: 1081220..1082263 (+)
• Length: 347 a.a.
• NCBI ID: WP_002481663.1
• Uniprot ID: -
• Organism: Staphylococcus simulans strain IVB6189
• Function: repress expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 1076220..1087263

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
MUA87_RS04820 (MUA87_04820)	-	1077223..1077942 (+)	720	WP_023015863.1	type 1 glutamine amidotransferase	-
MUA87_RS04825 (MUA87_04825)	-	1078025..1079011 (-)	987	WP_002481667.1	aromatic acid exporter family protein	-
MUA87_RS04830 (MUA87_04830)	map	1079231..1079995 (+)	765	WP_002481666.1	type I methionyl aminopeptidase	-
MUA87_RS04835 (MUA87_04835)	-	1080111..1080506 (+)	396	WP_002481665.1	hypothetical protein	-
MUA87_RS04840 (MUA87_04840)	liaF	1080522..1081223 (+)	702	WP_002481664.1	cell wall-active antibiotics response protein LiaF	-
MUA87_RS04845 (MUA87_04845)	vraS	1081220..1082263 (+)	1044	WP_002481663.1	sensor histidine kinase	Regulator
MUA87_RS04850 (MUA87_04850)	vraR	1082253..1082882 (+)	630	WP_002481662.1	response regulator transcription factor	Regulator
MUA87_RS04855 (MUA87_04855)	-	1082953..1083531 (-)	579	WP_262551351.1	carbonic anhydrase	-
MUA87_RS04860 (MUA87_04860)	-	1083739..1084815 (-)	1077	WP_002481660.1	YihY/virulence factor BrkB family protein	-
MUA87_RS04865 (MUA87_04865)	-	1084946..1085236 (-)	291	WP_262551352.1	YtxH domain-containing protein	-
MUA87_RS04870 (MUA87_04870)	-	1085244..1085708 (-)	465	WP_023015860.1	low molecular weight protein-tyrosine-phosphatase	-
MUA87_RS04875 (MUA87_04875)	-	1085932..1086138 (+)	207	WP_002481657.1	DUF1128 family protein	-

Sequence

Protein

• Length: 347 a.a.
• Molecular weight: 39897.15 Da
• Isoelectric Point: 4.8944

>NTDB_id=675397 MUA87_RS04845 WP_002481663.1 1081220..1082263(+) (vraS) [Staphylococcus simulans strain IVB6189]
MNHYIRAIGSMLILNYSILAIFFFIDKVFVNIIYFQGMFYTQIFGIPVFLFLNIIVILMSIIVGSVLAYKVNEQNDWIKT
QIEHSIEGEVVGINDQNIELYQETLDIYHTLVPLNQELHRLRIKTQDLTNETYNLNDVKVKKIIEDERQRLARELHDSVS
QQLFAASMMLSAIKESPLEPPLDQQIPTLEKMVQDSQLEMRALLLHLRPLGLKDRSLGEGIKDLVVDLQKKVPMKVVYDI
EDFEVPKGIEDHLFRITQEGISNTLRHAEGTKLTIDLFNKDDYLLLRIQDDGKGFDVDEKMEKSYGLKNMRERALEIGAT
LHIVSLPGAGTRIEVKAPLNKEENDGD

Nucleotide

• Length: 1044 bp

>NTDB_id=675397 MUA87_RS04845 WP_002481663.1 1081220..1082263(+) (vraS) [Staphylococcus simulans strain IVB6189]
ATGAACCACTATATCAGAGCCATCGGTTCGATGCTGATATTGAACTATAGTATATTAGCGATTTTCTTTTTTATAGACAA
AGTGTTCGTCAACATCATCTACTTTCAAGGAATGTTTTACACGCAGATTTTCGGCATTCCTGTTTTCTTATTTTTAAATA
TTATAGTGATTTTGATGAGTATTATTGTTGGTTCTGTGTTAGCGTATAAAGTGAACGAACAAAATGATTGGATTAAAACA
CAAATTGAACATTCCATTGAAGGGGAAGTTGTCGGTATTAATGATCAAAATATCGAACTCTACCAAGAAACTTTGGATAT
CTATCATACACTTGTGCCATTAAACCAAGAGTTACATCGACTACGTATTAAAACACAAGATTTGACCAACGAAACATATA
ATTTAAATGACGTTAAAGTGAAGAAAATTATAGAAGATGAACGCCAGCGTTTAGCTAGGGAATTGCATGATTCAGTTAGT
CAGCAATTATTTGCGGCAAGTATGATGTTATCAGCGATTAAGGAATCACCACTTGAACCGCCGCTTGATCAGCAAATTCC
GACACTAGAAAAGATGGTACAAGATTCGCAACTAGAAATGCGTGCATTGTTATTACATTTAAGACCGCTTGGCTTAAAAG
ATCGCTCACTTGGGGAAGGAATTAAAGATCTTGTTGTGGACTTACAAAAGAAAGTGCCTATGAAAGTAGTTTATGATATT
GAAGACTTTGAGGTACCAAAAGGCATAGAAGATCATTTATTCCGTATCACCCAAGAAGGGATTTCCAATACACTGCGACA
TGCAGAAGGCACAAAATTAACGATAGATTTATTTAATAAAGATGATTATCTGTTATTGCGTATTCAAGATGATGGTAAAG
GCTTTGATGTAGATGAAAAAATGGAGAAAAGCTATGGATTGAAGAATATGCGAGAGCGAGCATTAGAAATCGGGGCAACA
CTGCATATTGTTTCTTTGCCTGGGGCAGGGACAAGAATTGAAGTGAAGGCTCCATTGAATAAGGAGGAAAATGATGGCGA
TTAA

Domains

Predicted by InterproScan.

• Histidine kinase (HisKA_3) (147-210)

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (249-340)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vraS	Staphylococcus aureus N315	86.167	100	0.862