Detailed information    

insolico Bioinformatically predicted

Overview

Name   agrA   Type   Regulator
Locus tag   SAFDA_RS10400 Genome accession   NZ_AP014942
Coordinates   2062171..2062887 (+) Length   238 a.a.
NCBI ID   WP_000688498.1    Uniprot ID   Q2VG52
Organism   Staphylococcus aureus strain FDA209P     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 2057171..2067887
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SAFDA_RS15275 hld 2058238..2058318 (-) 81 WP_000046022.1 delta-hemolysin -
  SAFDA_RS15075 - 2058608..2058739 (+) 132 Protein_1972 histidine kinase -
  SAFDA_RS10380 (SAFDA_1908) - 2058860..2060179 (+) 1320 WP_001808146.1 ISL3-like element IS1181 family transposase -
  SAFDA_RS10385 (SAFDA_1909) agrB 2060255..2060698 (+) 444 Protein_1974 accessory gene regulator AgrB -
  SAFDA_RS10390 (SAFDA_1910) agrD 2060695..2060835 (+) 141 WP_001093929.1 cyclic lactone autoinducer peptide AgrD -
  SAFDA_RS10395 agrC 2060860..2062152 (+) 1293 WP_001657119.1 quorum-sensing sensor histidine kinase AgrC -
  SAFDA_RS10400 (SAFDA_1912) agrA 2062171..2062887 (+) 717 WP_000688498.1 quorum-sensing response regulator AgrA Regulator
  SAFDA_RS10405 - 2062959..2063068 (+) 110 Protein_1978 hypothetical protein -
  SAFDA_RS10410 (SAFDA_1913) - 2063256..2064215 (-) 960 WP_001253302.1 carbohydrate kinase family protein -
  SAFDA_RS10415 (SAFDA_1914) - 2064212..2065696 (-) 1485 WP_042727666.1 sucrose-6-phosphate hydrolase -
  SAFDA_RS10420 (SAFDA_1915) - 2065845..2066795 (-) 951 WP_000790324.1 LacI family DNA-binding transcriptional regulator -

Sequence

Protein


Download         Length: 238 a.a.        Molecular weight: 27933.91 Da        Isoelectric Point: 6.0927

>NTDB_id=67501 SAFDA_RS10400 WP_000688498.1 2062171..2062887(+) (agrA) [Staphylococcus aureus strain FDA209P]
MKIFICEDDPKQRENMVTIIKNYIMIEEKPMEIALATDNPYEVLEQAKNMNDIGCYFLDIQLSTDINGIKLGSEIRKHDP
VGNIIFVTSHSELTYLTFVYKVAAMDFIFKDDPAELRTRIIDCLETAHTRLQLLSRDNSVETIELKRGSNSVYVQYDDIM
FFESSTKSHRLIAHLDNRQIEFYGNLKELSQLDDRFFRCHNSFVVNRHNIESIDSKERIVYFKNKEHCYASVRNVKKI

Nucleotide


Download         Length: 717 bp        

>NTDB_id=67501 SAFDA_RS10400 WP_000688498.1 2062171..2062887(+) (agrA) [Staphylococcus aureus strain FDA209P]
ATGAAAATTTTCATTTGCGAAGACGATCCAAAACAAAGAGAAAACATGGTTACCATTATTAAAAATTATATAATGATAGA
AGAAAAGCCTATGGAAATTGCCCTCGCAACTGATAATCCTTATGAGGTGCTTGAGCAAGCTAAAAATATGAATGACATAG
GCTGTTACTTTTTAGATATTCAACTTTCAACTGATATTAATGGTATCAAATTAGGCAGTGAAATTCGTAAGCATGACCCA
GTTGGTAACATTATTTTCGTTACGAGTCACAGTGAACTTACCTATTTAACATTTGTCTACAAAGTTGCAGCGATGGATTT
TATTTTTAAAGATGATCCAGCAGAATTAAGAACTCGAATTATAGATTGTTTAGAAACTGCACATACACGCTTACAATTAT
TATCAAGAGATAATAGCGTTGAAACGATTGAATTAAAACGTGGCAGTAATTCAGTGTATGTTCAATATGATGATATTATG
TTTTTTGAATCATCAACAAAATCGCACAGACTCATTGCCCATTTAGATAACCGTCAAATTGAATTTTATGGTAATTTAAA
AGAACTGAGTCAATTAGATGATCGTTTCTTTAGATGTCATAATAGCTTTGTCGTCAATCGCCATAATATTGAATCTATAG
ATTCGAAAGAGCGAATTGTCTATTTTAAAAATAAAGAACACTGCTATGCATCGGTGAGAAACGTTAAAAAAATATAA

Domains

Predicted by InterproScan.

LytTr DNA-binding domain (LytTR)

(151-237)

Response regulator receiver domain (Response_reg)

(3-120)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q2VG52

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  agrA Staphylococcus aureus N315

99.58

100

0.996

Multiple sequence alignment