Detailed information NTG0674214

Bioinformatically predicted

Overview

• Name: vraS
• Type: Regulator
• Locus tag: MUO44_RS09495
• Genome accession: NZ_CP094928
• Coordinates: 1947113..1948156 (-)
• Length: 347 a.a.
• NCBI ID: WP_001017131.1
• Uniprot ID: A0A0D1IMN4
• Organism: Staphylococcus aureus strain 8
• Function: repress expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 1942113..1953156

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
MUO44_RS09465 (MUO44_09465)	-	1942541..1943797 (-)	1257	WP_001793428.1	aminopeptidase	-
MUO44_RS09470 (MUO44_09470)	-	1943800..1944000 (-)	201	WP_000180460.1	DUF1128 family protein	-
MUO44_RS09475 (MUO44_09475)	-	1944147..1944611 (+)	465	WP_000228666.1	low molecular weight protein-tyrosine-phosphatase	-
MUO44_RS09480 (MUO44_09480)	-	1944618..1944893 (+)	276	WP_000428172.1	YtxH domain-containing protein	-
MUO44_RS09485 (MUO44_09485)	-	1945171..1946382 (+)	1212	WP_000037091.1	YihY/virulence factor BrkB family protein	-
MUO44_RS09490 (MUO44_09490)	vraR	1946494..1947123 (-)	630	WP_000153535.1	two-component system response regulator VraR	Regulator
MUO44_RS09495 (MUO44_09495)	vraS	1947113..1948156 (-)	1044	WP_001017131.1	sensor histidine kinase	Regulator
MUO44_RS09500 (MUO44_09500)	liaF	1948153..1948854 (-)	702	WP_000149064.1	cell wall-active antibiotics response protein LiaF	-
MUO44_RS09505 (MUO44_09505)	-	1948869..1949255 (-)	387	WP_001110179.1	hypothetical protein	-
MUO44_RS09510 (MUO44_09510)	map	1949472..1950230 (-)	759	WP_000636142.1	type I methionyl aminopeptidase	-
MUO44_RS09515 (MUO44_09515)	-	1950761..1951747 (+)	987	WP_000999713.1	aromatic acid exporter family protein	-
MUO44_RS09520 (MUO44_09520)	-	1952178..1952591 (-)	414	WP_001837236.1	hypothetical protein	-
MUO44_RS09525 (MUO44_09525)	-	1952620..1952731 (-)	112	Protein_1837	hypothetical protein	-

Sequence

Protein

• Length: 347 a.a.
• Molecular weight: 40044.52 Da
• Isoelectric Point: 6.0577

>NTDB_id=674214 MUO44_RS09495 WP_001017131.1 1947113..1948156(-) (vraS) [Staphylococcus aureus strain 8]
MNHYIRTIGSMLILVYSMLAAFLFIDKVFVNIIYFQGMFYTQIFGIPVFLFLNLIIILLCIIVGSVLAYKINQQNDWIKT
QIERSMEGETVGINDQNIEIYSETLDLYHTLVPLNQELHKLRLKTQNLTNENYNINDVKVKKIIEDERQRLARELHDSVS
QQLFAASMMLSAIKETKLEPPLDQQIPILEKMVQDSQLEMRALLLHLRPLGLKDKSLGEGIKDLVIDLQKKVPMKVVHEI
QDFKVPKGIEDHLFRITQEAISNTLRHSNGTKVTVELFNKDDYLLLRIQDNGKGFNVDEKLEQSYGLKNMRERALEIGAT
FHIVSLPDSGTRIEVKAPLNKEDSYDD

Nucleotide

• Length: 1044 bp

>NTDB_id=674214 MUO44_RS09495 WP_001017131.1 1947113..1948156(-) (vraS) [Staphylococcus aureus strain 8]
ATGAACCACTACATTAGAACAATTGGTTCAATGCTCATCTTAGTATATAGCATGCTAGCTGCATTTCTATTCATCGATAA
AGTTTTTGTAAATATCATCTATTTTCAAGGTATGTTTTATACACAAATATTCGGAATACCAGTCTTTTTATTTTTAAATC
TCATCATCATATTATTGTGTATTATTGTTGGTTCGGTACTCGCATACAAAATCAATCAGCAAAATGATTGGATTAAGACG
CAAATTGAGCGTTCAATGGAAGGCGAAACAGTTGGCATTAATGATCAAAATATAGAAATATATAGTGAAACGTTAGATTT
ATACCATACACTCGTACCTTTAAATCAAGAATTGCATAAGTTGCGACTTAAAACTCAAAATTTAACCAATGAAAATTATA
ATATTAATGATGTGAAAGTTAAAAAGATTATTGAAGATGAACGTCAAAGACTAGCTCGAGAACTTCACGATTCTGTTAGT
CAGCAACTTTTTGCGGCAAGTATGATGCTTTCTGCTATCAAAGAAACGAAGTTAGAACCACCATTAGACCAACAAATTCC
GATTTTAGAGAAAATGGTTCAAGATTCGCAGTTAGAAATGCGTGCTTTGCTGTTACATTTAAGACCGCTTGGTTTAAAAG
ACAAATCTTTAGGTGAGGGTATTAAAGATTTAGTTATTGATTTACAAAAAAAAGTGCCGATGAAAGTTGTGCATGAAATA
CAAGATTTTAAAGTGCCTAAAGGTATTGAAGATCATTTGTTCAGAATTACACAGGAAGCAATTTCGAATACATTGCGTCA
TTCAAACGGTACAAAAGTGACAGTAGAATTGTTTAATAAAGACGATTATTTATTGTTGAGAATTCAAGACAATGGTAAAG
GTTTTAATGTTGATGAAAAATTAGAACAAAGTTATGGACTTAAAAATATGCGTGAAAGAGCTTTGGAAATTGGTGCAACG
TTCCATATTGTATCATTGCCAGATTCAGGTACACGTATCGAGGTGAAAGCACCTTTAAATAAGGAGGATTCGTATGACGA
TTAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (249-340)

• Histidine kinase (HisKA_3) (147-210)

3D structure

• AlphaFold DB: A0A0D1IMN4

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vraS	Staphylococcus aureus N315	100	100	1