Detailed information    

insolico Bioinformatically predicted

Overview

Name   sigH   Type   Regulator
Locus tag   MUO49_RS12150 Genome accession   NZ_CP094924
Coordinates   2428482..2429051 (+) Length   189 a.a.
NCBI ID   WP_000872874.1    Uniprot ID   -
Organism   Staphylococcus aureus strain 18     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 2423482..2434051
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  MUO49_RS12125 (MUO49_12110) cysE 2424695..2425342 (+) 648 WP_001805237.1 serine O-acetyltransferase -
  MUO49_RS12130 (MUO49_12115) cysS 2425326..2426726 (+) 1401 WP_000631974.1 cysteine--tRNA ligase -
  MUO49_RS12135 (MUO49_12120) - 2426719..2427123 (+) 405 WP_000370182.1 Mini-ribonuclease 3 -
  MUO49_RS12140 (MUO49_12125) rlmB 2427131..2427877 (+) 747 WP_000390332.1 23S rRNA (guanosine(2251)-2'-O)-methyltransferase RlmB -
  MUO49_RS12145 (MUO49_12130) - 2427877..2428401 (+) 525 WP_000664738.1 NYN domain-containing protein -
  MUO49_RS12150 (MUO49_12135) sigH 2428482..2429051 (+) 570 WP_000872874.1 RNA polymerase sigma factor Regulator
  MUO49_RS12155 (MUO49_12140) rpmG 2429166..2429309 (+) 144 WP_001788193.1 50S ribosomal protein L33 -
  MUO49_RS12160 (MUO49_12145) secE 2429365..2429547 (+) 183 WP_001074473.1 preprotein translocase subunit SecE -
  MUO49_RS12165 (MUO49_12150) nusG 2429560..2430108 (+) 549 WP_001288302.1 transcription termination/antitermination protein NusG -
  MUO49_RS12170 (MUO49_12155) rplK 2430289..2430711 (+) 423 WP_001085792.1 50S ribosomal protein L11 -
  MUO49_RS12175 (MUO49_12160) rplA 2430919..2431611 (+) 693 WP_001074619.1 50S ribosomal protein L1 -
  MUO49_RS12180 (MUO49_12165) rplJ 2431884..2432384 (+) 501 WP_001273085.1 50S ribosomal protein L10 -
  MUO49_RS12185 (MUO49_12170) rplL 2432427..2432795 (+) 369 WP_001273586.1 50S ribosomal protein L7/L12 -
  MUO49_RS12190 (MUO49_12175) - 2432970..2433578 (+) 609 WP_000020304.1 class I SAM-dependent methyltransferase -

Sequence

Protein


Download         Length: 189 a.a.        Molecular weight: 23043.97 Da        Isoelectric Point: 9.6030

>NTDB_id=674048 MUO49_RS12150 WP_000872874.1 2428482..2429051(+) (sigH) [Staphylococcus aureus strain 18]
MKYDLTTQDSTIKRNNAINDKDFEKLVMDLQPLIIRRIKTFGFNHYDLEDLYQEILIRMYRSVQTFDFSGEQPFTNYVQC
LITSVKYDYLRKYLATNKRMDNLINEYRVTYPCAIKRYDVENNYLNKLAIKELICQFKYLSAFEKDVMYLMCKQYKPREI
AQLMHVKEKVIYNAIQRCKNKIKRYFKMI

Nucleotide


Download         Length: 570 bp        

>NTDB_id=674048 MUO49_RS12150 WP_000872874.1 2428482..2429051(+) (sigH) [Staphylococcus aureus strain 18]
TTGAAATACGATTTGACAACTCAAGACAGTACAATCAAACGTAACAATGCAATAAATGATAAAGACTTCGAAAAGTTAGT
AATGGATCTACAACCATTAATTATTCGACGCATCAAAACATTTGGATTTAATCATTATGATTTAGAAGACTTATATCAAG
AAATACTTATACGGATGTATAGGTCGGTCCAAACATTTGATTTTAGTGGAGAGCAGCCTTTCACAAATTATGTTCAATGT
TTAATTACGTCTGTAAAGTATGATTATTTGAGAAAATATTTAGCTACAAATAAAAGAATGGATAATTTGATTAATGAATA
TAGAGTTACGTATCCATGTGCAATAAAGCGTTATGATGTTGAAAACAATTATTTGAATAAATTAGCAATTAAAGAGTTGA
TTTGTCAGTTTAAGTATTTGAGTGCATTTGAAAAAGATGTCATGTATTTAATGTGTAAACAATATAAGCCGAGAGAAATT
GCTCAATTGATGCATGTAAAAGAGAAAGTGATTTATAATGCGATACAACGATGTAAAAATAAAATAAAACGTTATTTCAA
AATGATTTGA

Domains

Predicted by InterproScan.

Sigma-70 region 2 (Sigma70_r2)

(26-92)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  sigH Staphylococcus aureus N315

98.413

100

0.984
  sigH Staphylococcus aureus MW2

98.413

100

0.984