Detailed information    

insolico Bioinformatically predicted

Overview

Name   agrA   Type   Regulator
Locus tag   MUO49_RS05545 Genome accession   NZ_CP094924
Coordinates   1099303..1100019 (+) Length   238 a.a.
NCBI ID   WP_000688498.1    Uniprot ID   Q2VG52
Organism   Staphylococcus aureus strain 18     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 1094303..1105019
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  MUO49_RS05515 (MUO49_05500) - 1094523..1095149 (+) 627 WP_000522384.1 nitroreductase family protein -
  MUO49_RS05520 (MUO49_05505) - 1095510..1096295 (+) 786 WP_000867940.1 carbon-nitrogen family hydrolase -
  MUO49_RS05525 (MUO49_05510) hld 1096891..1096971 (-) 81 WP_000046022.1 delta-hemolysin -
  MUO49_RS05530 (MUO49_05515) agrB 1097261..1097830 (+) 570 WP_001105707.1 accessory gene regulator AgrB -
  MUO49_RS05535 (MUO49_05520) - 1097827..1097967 (+) 141 WP_001093929.1 cyclic lactone autoinducer peptide -
  MUO49_RS05540 (MUO49_05525) - 1097992..1099284 (+) 1293 WP_277558193.1 GHKL domain-containing protein -
  MUO49_RS05545 (MUO49_05530) agrA 1099303..1100019 (+) 717 WP_000688498.1 LytTR family DNA-binding domain-containing protein Regulator
  MUO49_RS05550 (MUO49_05535) - 1100091..1100200 (+) 110 Protein_1067 hypothetical protein -
  MUO49_RS05555 (MUO49_05540) - 1100388..1101347 (-) 960 WP_001253302.1 carbohydrate kinase -
  MUO49_RS05560 (MUO49_05545) - 1101344..1102828 (-) 1485 WP_000141426.1 sucrose-6-phosphate hydrolase -
  MUO49_RS05565 (MUO49_05550) - 1102977..1103927 (-) 951 WP_024273570.1 LacI family DNA-binding transcriptional regulator -

Sequence

Protein


Download         Length: 238 a.a.        Molecular weight: 27933.91 Da        Isoelectric Point: 6.0927

>NTDB_id=674035 MUO49_RS05545 WP_000688498.1 1099303..1100019(+) (agrA) [Staphylococcus aureus strain 18]
MKIFICEDDPKQRENMVTIIKNYIMIEEKPMEIALATDNPYEVLEQAKNMNDIGCYFLDIQLSTDINGIKLGSEIRKHDP
VGNIIFVTSHSELTYLTFVYKVAAMDFIFKDDPAELRTRIIDCLETAHTRLQLLSRDNSVETIELKRGSNSVYVQYDDIM
FFESSTKSHRLIAHLDNRQIEFYGNLKELSQLDDRFFRCHNSFVVNRHNIESIDSKERIVYFKNKEHCYASVRNVKKI

Nucleotide


Download         Length: 717 bp        

>NTDB_id=674035 MUO49_RS05545 WP_000688498.1 1099303..1100019(+) (agrA) [Staphylococcus aureus strain 18]
ATGAAAATTTTCATTTGCGAAGACGATCCAAAACAAAGAGAAAACATGGTTACCATTATTAAAAATTATATAATGATAGA
AGAAAAGCCTATGGAAATTGCCCTCGCAACTGATAATCCTTATGAGGTGCTTGAGCAAGCTAAAAATATGAATGACATAG
GCTGTTACTTTTTAGATATTCAACTTTCAACTGATATTAATGGTATCAAATTAGGCAGTGAAATTCGTAAGCATGACCCA
GTTGGTAACATTATTTTCGTTACGAGTCACAGTGAACTTACCTATTTAACATTTGTCTACAAAGTTGCAGCGATGGATTT
TATTTTTAAAGATGATCCAGCAGAATTAAGAACTCGAATTATAGATTGTTTAGAAACTGCACATACACGCTTACAATTAT
TATCAAGAGATAATAGCGTTGAAACGATTGAATTAAAACGTGGCAGTAATTCAGTGTATGTTCAATATGATGATATTATG
TTTTTTGAATCATCAACAAAATCGCACAGACTCATTGCCCATTTAGATAACCGTCAAATTGAATTTTATGGTAATTTAAA
AGAACTGAGTCAATTAGATGATCGTTTCTTTAGATGTCATAATAGCTTTGTCGTCAATCGCCATAATATTGAATCTATAG
ATTCGAAAGAGCGAATTGTCTATTTTAAAAATAAAGAACACTGCTATGCATCGGTGAGAAACGTTAAAAAAATATAA

Domains

Predicted by InterproScan.

LytTr DNA-binding domain (LytTR)

(151-237)

Response regulator receiver domain (Response_reg)

(3-120)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q2VG52

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  agrA Staphylococcus aureus N315

99.58

100

0.996