Detailed information NTG0673736

Bioinformatically predicted

Overview

• Name: vraS
• Type: Regulator
• Locus tag: MTX75_RS09420
• Genome accession: NZ_CP094857
• Coordinates: 1924019..1925062 (-)
• Length: 347 a.a.
• NCBI ID: WP_001017131.1
• Uniprot ID: A0A0D1IMN4
• Organism: Staphylococcus aureus strain ATCC 29213
• Function: repress expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 1919019..1930062

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
MTX75_RS09390 (MTX75_09390)	-	1919440..1920696 (-)	1257	WP_001795108.1	aminopeptidase	-
MTX75_RS09395 (MTX75_09395)	-	1920699..1920899 (-)	201	WP_000180460.1	DUF1128 family protein	-
MTX75_RS09400 (MTX75_09400)	-	1921046..1921510 (+)	465	WP_000228666.1	low molecular weight protein-tyrosine-phosphatase	-
MTX75_RS09405 (MTX75_09405)	-	1921517..1921792 (+)	276	WP_000428172.1	YtxH domain-containing protein	-
MTX75_RS09410 (MTX75_09410)	-	1922070..1923287 (+)	1218	WP_000037075.1	YihY/virulence factor BrkB family protein	-
MTX75_RS09415 (MTX75_09415)	vraR	1923400..1924029 (-)	630	WP_000153535.1	two-component system response regulator VraR	Regulator
MTX75_RS09420 (MTX75_09420)	vraS	1924019..1925062 (-)	1044	WP_001017131.1	sensor histidine kinase	Regulator
MTX75_RS09425 (MTX75_09425)	liaF	1925059..1925760 (-)	702	WP_000149064.1	cell wall-active antibiotics response protein LiaF	-
MTX75_RS09430 (MTX75_09430)	-	1925775..1926161 (-)	387	WP_001110179.1	hypothetical protein	-
MTX75_RS09435 (MTX75_09435)	map	1926378..1927136 (-)	759	WP_000636142.1	type I methionyl aminopeptidase	-
MTX75_RS09440 (MTX75_09440)	-	1927667..1928653 (+)	987	WP_031768943.1	aromatic acid exporter family protein	-
MTX75_RS09445 (MTX75_09445)	-	1929084..1929497 (-)	414	WP_001557448.1	hypothetical protein	-
MTX75_RS09450 (MTX75_09450)	-	1929526..1929636 (-)	111	WP_001790257.1	hypothetical protein	-

Sequence

Protein

• Length: 347 a.a.
• Molecular weight: 40044.52 Da
• Isoelectric Point: 6.0577

>NTDB_id=673736 MTX75_RS09420 WP_001017131.1 1924019..1925062(-) (vraS) [Staphylococcus aureus strain ATCC 29213]
MNHYIRTIGSMLILVYSMLAAFLFIDKVFVNIIYFQGMFYTQIFGIPVFLFLNLIIILLCIIVGSVLAYKINQQNDWIKT
QIERSMEGETVGINDQNIEIYSETLDLYHTLVPLNQELHKLRLKTQNLTNENYNINDVKVKKIIEDERQRLARELHDSVS
QQLFAASMMLSAIKETKLEPPLDQQIPILEKMVQDSQLEMRALLLHLRPLGLKDKSLGEGIKDLVIDLQKKVPMKVVHEI
QDFKVPKGIEDHLFRITQEAISNTLRHSNGTKVTVELFNKDDYLLLRIQDNGKGFNVDEKLEQSYGLKNMRERALEIGAT
FHIVSLPDSGTRIEVKAPLNKEDSYDD

Nucleotide

• Length: 1044 bp

>NTDB_id=673736 MTX75_RS09420 WP_001017131.1 1924019..1925062(-) (vraS) [Staphylococcus aureus strain ATCC 29213]
ATGAACCACTACATTAGAACAATTGGTTCAATGCTCATCTTAGTATATAGCATGCTAGCTGCATTTCTATTCATCGATAA
AGTTTTTGTAAATATCATCTATTTTCAAGGTATGTTTTATACACAAATATTCGGAATACCAGTCTTTTTATTTTTAAATC
TCATCATCATATTATTGTGTATTATTGTTGGTTCGGTACTCGCATACAAAATCAATCAGCAAAATGATTGGATTAAGACG
CAAATTGAGCGTTCAATGGAAGGCGAAACAGTTGGCATTAATGATCAAAATATAGAAATATATAGTGAAACGTTAGATTT
ATACCATACACTCGTACCTTTAAATCAAGAATTGCATAAGTTGCGACTTAAAACTCAAAACTTAACCAATGAAAATTATA
ATATTAATGATGTGAAAGTTAAAAAGATTATTGAAGATGAACGTCAAAGACTAGCTCGAGAACTTCACGATTCTGTTAGT
CAGCAACTTTTTGCGGCAAGTATGATGCTTTCTGCTATCAAAGAAACGAAGTTAGAACCACCATTAGACCAACAAATTCC
GATTTTAGAGAAAATGGTTCAAGATTCGCAGTTAGAAATGCGTGCTTTGCTGTTACATTTAAGACCGCTTGGTTTAAAAG
ACAAATCTTTAGGTGAGGGTATTAAAGATTTAGTTATTGATTTACAAAAAAAAGTGCCAATGAAAGTTGTGCATGAAATA
CAAGATTTTAAAGTGCCTAAAGGTATTGAAGATCATTTGTTCAGAATTACACAGGAAGCAATTTCGAATACATTGCGTCA
TTCAAACGGTACAAAAGTGACAGTAGAATTGTTTAATAAAGACGATTATTTATTGTTGAGAATTCAAGATAATGGTAAAG
GTTTTAATGTTGATGAAAAATTAGAACAAAGTTATGGACTTAAAAATATGCGTGAAAGAGCTTTGGAAATTGGTGCAACG
TTCCATATTGTATCATTGCCAGATTCAGGTACACGTATCGAGGTGAAAGCACCTTTAAATAAGGAGGATTCGTATGACGA
TTAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (249-340)

• Histidine kinase (HisKA_3) (147-210)

3D structure

• AlphaFold DB: A0A0D1IMN4

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vraS	Staphylococcus aureus N315	100	100	1