Detailed information NTG0673619

Bioinformatically predicted

Overview

• Name: ccrB
• Type: Machinery gene
• Locus tag: MTX62_RS00260
• Genome accession: NZ_CP094853
• Coordinates: 57375..59003 (-)
• Length: 542 a.a.
• NCBI ID: WP_001186596.1
• Uniprot ID: -
• Organism: Staphylococcus aureus strain NY2010
• Function: promote SCCmec transfer (predicted from homology) Homologous recombination

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type	MGE coordinates	Gene coordinates	Relative position	Distance (bp)
SCCmec	39300..60370	57375..59003	within	0

Gene organization within MGE regions

Location: 39300..60370

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
MTX62_RS00160 (MTX62_00160)	mecA	39300..41309 (-)	2010	WP_078065777.1	PBP2a family beta-lactam-resistant peptidoglycan transpeptidase MecA	-
MTX62_RS00165 (MTX62_00165)	mecR1	41406..43163 (+)	1758	WP_000952923.1	beta-lactam sensor/signal transducer MecR1	-
MTX62_RS00170 (MTX62_00170)	mecI	43163..43534 (+)	372	Protein_32	mecA-type methicillin resistance repressor MecI	-
MTX62_RS00175 (MTX62_00175)	psm-mec	43619..43687 (-)	69	WP_014532405.1	phenol-soluble modulin PSM-mec	-
MTX62_RS00180 (MTX62_00180)	-	44007..45155 (+)	1149	WP_000427807.1	ROK family transcriptional regulator	-
MTX62_RS00185 (MTX62_00185)	cstB	45269..46603 (-)	1335	Protein_35	persulfide dioxygenase-sulfurtransferase CstB	-
MTX62_RS00190 (MTX62_00190)	-	46636..47700 (-)	1065	WP_000438836.1	DsrE/DsrF/DrsH-like family protein	-
MTX62_RS00195 (MTX62_00195)	cstR	47836..48096 (+)	261	WP_000220507.1	persulfide-sensing transcriptional repressor CstR	-
MTX62_RS00200 (MTX62_00200)	-	48096..48734 (+)	639	Protein_38	sulfite exporter TauE/SafE family protein	-
MTX62_RS00210 (MTX62_00210)	-	49008..49625 (-)	618	WP_000562107.1	CadD family cadmium resistance transporter	-
MTX62_RS00215 (MTX62_00215)	-	49706..52120 (-)	2415	WP_000378485.1	cadmium-translocating P-type ATPase CadA	-
MTX62_RS00220 (MTX62_00220)	-	52113..52478 (-)	366	WP_000159127.1	metalloregulator ArsR/SmtB family transcription factor	-
MTX62_RS00225 (MTX62_00225)	-	52716..53093 (-)	378	WP_000361060.1	DUF6262 family protein	-
MTX62_RS00230 (MTX62_00230)	-	53100..54992 (-)	1893	WP_014533070.1	site-specific integrase	-
MTX62_RS00235 (MTX62_00235)	-	55188..55511 (-)	324	WP_000088091.1	JAB domain-containing protein	-
MTX62_RS00240 (MTX62_00240)	-	55504..55710 (-)	207	WP_001077283.1	hypothetical protein	-
MTX62_RS00245 (MTX62_00245)	-	55712..56233 (-)	522	WP_000836008.1	DUF1643 domain-containing protein	-
MTX62_RS00250 (MTX62_00250)	-	56252..56563 (-)	312	WP_000833212.1	DUF960 family protein	-
MTX62_RS00255 (MTX62_00255)	-	56566..56904 (-)	339	WP_000171448.1	SAUGI family uracil-DNA glycosylase inhibitor	-
MTX62_RS00260 (MTX62_00260)	ccrB	57375..59003 (-)	1629	WP_001186596.1	recombinase family protein	Machinery gene
MTX62_RS00265 (MTX62_00265)	ccrA	59024..60370 (-)	1347	WP_000816499.1	recombinase family protein	Machinery gene

Sequence

Protein

• Length: 542 a.a.
• Molecular weight: 62274.15 Da
• Isoelectric Point: 9.7334

>NTDB_id=673619 MTX62_RS00260 WP_001186596.1 57375..59003(-) (ccrB) [Staphylococcus aureus strain NY2010]
MQQLKQKRVGIYVRVSTEIQSTEGYSIDGQINQIREYCDFNNFVVVDVYADRGISGKSMNRPELQRLLKDANEGQIDSVM
VYKTNRLARNTSDLLKIVEDLHRQNVEFFSLSERMEVNTSSGKLMLQILASFSEFERNNIVENVFMGQTRRAQEGYYQGN
LPLGYDKIPDSKHELMINQHEANIVKYIFESYAKGHGYRKIANALNHKGYVTKKGKPFSIGSVTYILSNPFYVGKIQFAK
YKDWNEKRRKGLNDKPIIAEGKHSPIIIQDLWDKVQLRKKQVSQKPQVHGKGTNLLTGIVHCPQCGAPMAASNTTNTLKD
GTKKRIRYYSCSNFRNKGSKVCSANSVRADVIEKYVMDQILEIVKSDKVINQVLERVNQENKVDIGALNHDIAYKQQQYD
EVSGKLHNLVKTIEDNPDLTSALKATIHQYETQLNDITNQMNQLKQQQNQEKLSYDTKQIAALLQRIFQNIESMDKAQLK
ALYLTVIDRIDIRKDGNHKKQFYVTLKLNNEIIKQLFNNTPLDEVLLSTSSLFLPQTLFLQI

Nucleotide

• Length: 1629 bp

>NTDB_id=673619 MTX62_RS00260 WP_001186596.1 57375..59003(-) (ccrB) [Staphylococcus aureus strain NY2010]
ATGCAACAACTCAAACAAAAACGTGTCGGTATCTATGTTCGTGTATCAACGGAAATCCAAAGTACTGAAGGCTATAGTAT
CGATGGACAAATCAATCAAATTCGAGAATATTGTGATTTCAATAACTTTGTTGTTGTAGATGTATACGCGGATAGAGGTA
TCTCTGGAAAATCTATGAACCGACCAGAACTACAACGTTTGTTAAAAGATGCGAACGAAGGTCAGATTGATTCTGTTATG
GTCTACAAAACAAACCGACTAGCACGTAACACTTCTGACTTACTCAAAATTGTTGAAGACCTTCATCGTCAAAATGTCGA
ATTCTTCAGCTTATCTGAGCGTATGGAAGTCAATACAAGCAGTGGTAAATTGATGCTACAAATTCTAGCGAGTTTTTCAG
AATTTGAAAGAAATAATATTGTCGAAAATGTATTCATGGGTCAAACCCGACGCGCTCAAGAAGGCTATTATCAAGGCAAT
TTGCCGCTGGGCTATGACAAAATACCGGATAGCAAGCATGAACTCATGATAAACCAACATGAAGCGAATATTGTCAAATA
TATATTTGAGTCATATGCTAAAGGCCACGGATATCGTAAAATTGCGAATGCACTCAATCACAAAGGATACGTGACTAAAA
AAGGAAAGCCTTTCAGTATTGGTTCAGTGACCTATATCTTATCTAATCCATTCTATGTTGGTAAAATTCAATTCGCAAAG
TACAAAGATTGGAATGAAAAGCGTCGTAAAGGGCTGAATGATAAACCAATAATAGCTGAAGGTAAGCATTCCCCTATTAT
TATTCAAGACTTATGGGATAAAGTCCAATTACGTAAAAAACAAGTCAGTCAAAAACCTCAAGTCCACGGTAAAGGAACTA
ATCTATTAACAGGTATCGTTCATTGTCCACAATGTGGTGCACCAATGGCAGCTAGTAACACAACGAACACATTGAAAGAT
GGTACCAAGAAGCGAATACGTTATTATTCTTGCAGTAACTTCCGAAACAAAGGCTCAAAAGTATGTTCTGCGAATAGCGT
TAGAGCTGATGTGATTGAGAAATACGTCATGGATCAAATACTCGAAATTGTCAAAAGTGATAAAGTCATTAACCAAGTCT
TAGAACGTGTCAATCAAGAAAATAAAGTCGATATTGGTGCATTGAACCACGATATCGCTTATAAACAACAACAATACGAT
GAAGTCAGCGGGAAACTCCATAATTTAGTTAAAACCATTGAAGATAATCCGGACCTAACATCTGCATTGAAAGCAACTAT
TCATCAATATGAAACACAACTCAATGACATTACAAATCAAATGAATCAACTCAAACAGCAACAAAATCAAGAGAAACTAT
CTTATGATACGAAACAAATCGCTGCCCTATTACAACGAATATTTCAAAATATAGAATCAATGGATAAAGCACAACTCAAA
GCATTATATCTTACAGTCATTGACCGTATTGATATTCGTAAAGACGGTAATCATAAAAAACAGTTCTACGTTACACTAAA
ACTCAATAATGAAATTATTAAACAACTTTTCAATAATACCCCTCTCGACGAAGTGCTCCTCAGCACTTCGTCTTTATTTT
TGCCTCAAACGCTCTTTCTTCAAATCTAA

Domains

Predicted by InterproScan.

• Resolvase, N terminal domain (Resolvase) (11-156)

• Recombinase (Recombinase) (180-280)

• Ogr/Delta-like zinc finger (Ogr_Delta) (301-356)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
ccrB	Staphylococcus aureus N315	86.531	100	0.865