Detailed information NTG0673545

Bioinformatically predicted

Overview

• Name: disA
• Type: Machinery gene
• Locus tag: OH775_RS22935
• Genome accession: NZ_CP109301
• Coordinates: 5039479..5040603 (+)
• Length: 374 a.a.
• NCBI ID: WP_406474895.1
• Uniprot ID: -
• Organism: Streptomyces sp. NBC_01615
• Function: homologous recombination (predicted from homology) Homologous recombination

Genomic Context

Location: 5034479..5045603

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
OH775_RS22920 (OH775_22870)	-	5035057..5035917 (+)	861	WP_327430651.1	hypothetical protein	-
OH775_RS22925 (OH775_22875)	-	5036038..5037804 (-)	1767	WP_406474892.1	BACON domain-containing protein	-
OH775_RS22930 (OH775_22880)	radA/sms	5038001..5039410 (+)	1410	WP_327430649.1	DNA repair protein RadA	Machinery gene
OH775_RS22935 (OH775_22885)	disA	5039479..5040603 (+)	1125	WP_406474895.1	DNA integrity scanning diadenylate cyclase DisA	Machinery gene
OH775_RS22940 (OH775_22890)	-	5040804..5041613 (-)	810	WP_406474897.1	hypothetical protein	-
OH775_RS22945 (OH775_22895)	-	5042038..5042946 (+)	909	WP_406474899.1	A/G-specific adenine glycosylase	-
OH775_RS22950 (OH775_22900)	-	5043244..5043795 (+)	552	WP_327430645.1	SigE family RNA polymerase sigma factor	-
OH775_RS22955 (OH775_22905)	-	5043783..5044430 (+)	648	WP_327430644.1	hypothetical protein	-
OH775_RS22960 (OH775_22910)	cseB	5044450..5045157 (+)	708	WP_327430643.1	two-component system response regulator CseB	-

Sequence

Protein

• Length: 374 a.a.
• Molecular weight: 40182.92 Da
• Isoelectric Point: 4.8595

>NTDB_id=673545 OH775_RS22935 WP_406474895.1 5039479..5040603(+) (disA) [Streptomyces sp. NBC_01615]
MAANDRAAAPGKSGGSSGADGLMRASLSAVAPGTALRDGLERILRGNTGGLIVLGWDKTVESMCTGGFVLDVEFTATRLR
ELCKLDGGIVIDKDITKILRAGVQLVPDPTIPTEETGTRHRTADRVSKQVDFPVVSVSQSMRLIALYVDGQRRVLEDSAA
ILSRANQALATLERYKLRLDEVAGTLSALEIEDLVTVRDVSAVAQRLEMVRRIATEIAEYVVELGTDGRLLALQLDELIA
GVEPERELVVRDYVPEPTAKRSRTVDEALSELDALSHAELLELSTVARALGYTGSPEALDSAVSPRGFRLLAKVPRLPGA
IIDRLVEHFGGLQKLLAASVDDLQAVDGVGEARARSVREGLSRLAESSILERYV

Nucleotide

• Length: 1125 bp

>NTDB_id=673545 OH775_RS22935 WP_406474895.1 5039479..5040603(+) (disA) [Streptomyces sp. NBC_01615]
GTGGCAGCCAACGACCGGGCAGCAGCTCCCGGAAAATCCGGTGGGAGCTCCGGTGCCGATGGCCTGATGCGCGCCTCACT
GAGCGCCGTGGCACCCGGCACAGCCCTGCGCGACGGGCTCGAGCGGATTCTCCGTGGCAACACGGGCGGACTCATCGTGC
TCGGCTGGGACAAGACCGTCGAGTCGATGTGCACCGGCGGTTTCGTGCTGGACGTCGAGTTCACCGCGACCCGCCTGCGG
GAGCTGTGCAAGCTCGACGGCGGCATCGTCATCGACAAGGACATCACCAAGATTCTGCGGGCGGGCGTGCAGCTCGTGCC
CGACCCGACGATCCCCACGGAGGAGACGGGCACGCGGCACCGCACCGCGGACCGGGTCTCCAAGCAGGTCGACTTCCCCG
TCGTCTCGGTCTCCCAGTCGATGCGCCTGATCGCGCTGTACGTCGACGGTCAGCGCCGCGTCCTGGAGGACTCGGCGGCG
ATCCTCTCCCGCGCCAACCAGGCCCTCGCGACCCTGGAGCGCTACAAACTCCGCCTCGACGAGGTCGCGGGAACGTTGTC
AGCGCTGGAGATCGAGGACCTCGTCACCGTCCGCGACGTGTCGGCTGTCGCCCAGCGCCTGGAGATGGTGCGGCGCATCG
CCACCGAGATCGCCGAGTACGTAGTCGAACTGGGCACCGACGGGCGTCTTCTCGCCCTCCAGCTGGACGAGTTGATCGCC
GGGGTCGAGCCCGAGCGCGAACTCGTCGTACGGGACTACGTGCCCGAGCCGACCGCCAAGCGCTCCCGCACGGTCGACGA
GGCTCTCTCCGAACTGGACGCGCTCAGCCACGCGGAGCTCCTCGAACTCTCCACCGTGGCACGGGCGCTGGGCTACACCG
GCTCCCCCGAGGCGCTGGACTCCGCAGTCTCCCCGCGCGGCTTCCGCCTCCTCGCCAAGGTGCCGCGCCTCCCCGGCGCG
ATCATCGACCGCCTTGTGGAGCACTTCGGCGGACTGCAGAAGCTGCTCGCCGCCAGCGTGGACGACCTGCAGGCGGTCGA
CGGGGTGGGCGAGGCGCGGGCGCGCAGTGTCCGCGAGGGGCTGTCGCGGCTGGCGGAGTCGTCGATTCTGGAACGGTACG
TCTAG

Domains

Predicted by InterProScan.

• Helix-hairpin-helix motif (HHH_2) (324-359)

• DisA bacterial checkpoint controller nucleotide-binding (DAC) (38-151)

• DisA bacterial checkpoint controller linker region (DisA-linker) (155-297)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
disA	Bacillus subtilis subsp. subtilis str. 168	45.152	96.524	0.436