Detailed information NTG0672876

Bioinformatically predicted

Overview

• Name: clpC
• Type: Regulator
• Locus tag: OH736_RS22725
• Genome accession: NZ_CP109258
• Coordinates: 5037918..5040518 (+)
• Length: 866 a.a.
• NCBI ID: WP_406159955.1
• Uniprot ID: -
• Organism: Streptomyces sp. NBC_01650
• Function: degradation of ComK; degradation of DegU (predicted from homology) Competence regulation

Genomic Context

Location: 5032918..5045518

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
OH736_RS22695 (OH736_22650)	dnaJ	5033569..5034753 (+)	1185	WP_124719624.1	molecular chaperone DnaJ	-
OH736_RS22700 (OH736_22655)	-	5034755..5035201 (+)	447	WP_072487850.1	heat shock protein transcriptional repressor HspR	-
OH736_RS22705 (OH736_22660)	-	5035339..5036325 (-)	987	WP_259927809.1	helix-turn-helix transcriptional regulator	-
OH736_RS22710 (OH736_22665)	-	5036466..5036837 (+)	372	WP_266690037.1	hypothetical protein	-
OH736_RS22715 (OH736_22670)	-	5036834..5037154 (+)	321	WP_072487853.1	(2Fe-2S)-binding protein	-
OH736_RS22720 (OH736_22675)	-	5037271..5037675 (-)	405	WP_124719621.1	pyridoxamine 5'-phosphate oxidase family protein	-
OH736_RS22725 (OH736_22680)	clpC	5037918..5040518 (+)	2601	WP_406159955.1	ATP-dependent chaperone ClpB	Regulator
OH736_RS22730 (OH736_22685)	-	5040924..5042189 (+)	1266	WP_406159957.1	MFS transporter	-
OH736_RS22735 (OH736_22690)	-	5042299..5042859 (+)	561	WP_124719618.1	YbjN domain-containing protein	-
OH736_RS22740 (OH736_22695)	-	5042932..5044110 (-)	1179	WP_266770374.1	pyridoxal phosphate-dependent aminotransferase	-
OH736_RS22745 (OH736_22700)	-	5044827..5045348 (+)	522	WP_406159959.1	DUF2617 family protein	-

Sequence

Protein

• Length: 866 a.a.
• Molecular weight: 94577.90 Da
• Isoelectric Point: 4.7121

>NTDB_id=672876 OH736_RS22725 WP_406159955.1 5037918..5040518(+) (clpC) [Streptomyces sp. NBC_01650]
MDAELTNKSRDAINAATSRAVKDGHPDLTPGHLLLALLAGEDNENITDLLAAVEADQIAVRTETERLLGAQPSVTGSTVA
PPQPNRELLAVISDAAQRAKELGDDYISTEHLLIGIAAEGGRAGEILGGQGASAKRLLDAFEKSRGGRRVTTPDPEGQYK
ALEKFGTDFTAAAREGKLDPVIGRDQEIRRVVQVLSRRTKNNPVLIGEPGVGKTAVVEGLAQRIVKGDVPESLKNKRLVS
LDLGAMVAGAKYRGEFEERLKTVLSEIKESDGQIITFIDELHTVVGAGAGGDSAMDAGNMLKPMLARGELRMVGATTLDE
YRERIEKDPALERRFQQVLVAEPSVEDTIAILRGLKGRYEAHHKVSIADSSLVAAATLSDRYITSRFLPDKAIDLVDEAA
SRLRMEIDSSPVEIDELQRAVDRLHMEELALKNETDPGSRQRLEKLRRDLADKEEELRGLNARWEKEKQGLNRVGELKER
LDELHGQAERAQRDGDFDTASKLLYGEIPGLERELAEASEAEQEAAKDTMVKEEVGPDDIADVVGSWTGIPAGRLLEGET
QKLLRMEDELGRRLIGQGEAVRAVSDAVRRTRAGIADPDRPTGSFLFLGPTGVGKTELAKALADFLFDDERAMVRIDMSE
YGEKHSVARLVGAPPGYVGYEEGGQLTEAVRRRPYSVVLLDEVEKAHPEVFDILLQVLDDGRLTDGQGRTVDFRNTILIL
TSNLGSQFLVDPLTKPEEKKERVLELVRASFKPEFLNRLDDLVVFSALSGDELAHIAKLQIDRLAKRLADRQLTLDVTPA
ALAWLAEEGNDPAYGARPLRRLIQTAIGDRLAKEILSGEVKDGDTVRVDRVGDDLLVGPATPDGAV

Nucleotide

• Length: 2601 bp

>NTDB_id=672876 OH736_RS22725 WP_406159955.1 5037918..5040518(+) (clpC) [Streptomyces sp. NBC_01650]
GTGGACGCCGAGCTGACCAACAAGAGCCGGGACGCCATCAACGCGGCCACCAGCAGGGCCGTGAAGGACGGGCACCCCGA
TCTGACCCCCGGGCACCTGCTGCTCGCGCTGCTCGCGGGCGAGGACAACGAGAACATCACCGATCTGCTCGCCGCCGTCG
AGGCCGACCAGATCGCCGTACGCACCGAGACCGAGCGGCTGCTGGGCGCCCAGCCCAGCGTCACCGGGTCCACCGTCGCC
CCGCCGCAGCCCAACCGCGAGCTGCTCGCCGTCATCAGCGACGCCGCGCAGCGCGCGAAGGAGCTCGGCGACGACTACAT
CTCCACCGAGCACCTGCTGATCGGCATCGCGGCCGAGGGCGGCCGCGCCGGTGAGATCCTCGGTGGGCAGGGGGCCAGTG
CGAAGAGGCTGCTGGACGCATTCGAGAAGAGCAGGGGAGGGCGCCGGGTGACCACACCCGACCCGGAGGGCCAGTACAAG
GCGCTGGAGAAGTTCGGTACGGACTTCACCGCCGCCGCACGCGAGGGCAAGCTCGACCCGGTCATCGGCCGTGACCAGGA
GATCCGCCGGGTCGTCCAGGTGCTCTCCCGCCGCACCAAGAACAACCCCGTGCTCATCGGCGAGCCCGGCGTCGGCAAGA
CGGCCGTCGTCGAGGGCCTCGCCCAGCGCATCGTCAAGGGCGACGTCCCCGAGTCCCTGAAGAACAAGCGGCTCGTCTCG
CTCGACCTCGGTGCGATGGTCGCGGGCGCCAAGTACCGCGGCGAGTTCGAGGAGCGGCTGAAGACCGTCCTCTCCGAGAT
CAAGGAGAGCGACGGGCAGATCATCACCTTCATCGACGAGCTGCACACCGTCGTGGGCGCGGGCGCCGGCGGCGACTCCG
CCATGGACGCCGGCAACATGCTCAAGCCGATGCTGGCCCGCGGCGAGCTCCGCATGGTCGGCGCGACGACGCTCGACGAG
TACCGCGAGCGGATCGAGAAGGACCCCGCCCTGGAGCGCCGCTTCCAGCAGGTACTGGTGGCCGAGCCGAGCGTCGAGGA
CACCATCGCGATCCTGCGCGGGCTCAAGGGCCGCTACGAGGCCCACCACAAGGTCTCCATCGCGGACTCGTCGCTGGTGG
CCGCCGCGACCCTCTCCGACCGCTACATCACCTCCCGCTTCCTCCCCGACAAGGCGATCGACCTGGTCGACGAGGCGGCG
TCCCGGCTGCGCATGGAGATCGACTCCTCGCCGGTCGAGATCGACGAGCTCCAGCGCGCCGTCGACCGCCTCCACATGGA
GGAGCTGGCCCTCAAGAACGAGACCGACCCCGGCTCCCGCCAGCGTCTGGAGAAGCTCCGCCGCGACCTCGCCGACAAGG
AGGAGGAGCTGCGCGGCCTCAACGCCCGCTGGGAGAAGGAGAAGCAGGGCCTCAACCGCGTCGGTGAGCTGAAGGAGCGC
CTCGACGAACTGCACGGCCAGGCCGAACGCGCCCAGCGCGACGGCGACTTCGACACCGCGTCCAAGCTGCTGTACGGGGA
GATCCCCGGTCTGGAGCGGGAGTTGGCGGAGGCGTCCGAGGCCGAGCAGGAGGCCGCCAAGGACACCATGGTCAAGGAGG
AGGTCGGCCCGGACGACATCGCCGATGTCGTCGGCTCCTGGACCGGCATCCCGGCCGGGCGTCTGCTGGAGGGCGAGACG
CAGAAGCTGCTGCGCATGGAGGACGAGCTCGGCAGGCGCCTGATCGGGCAGGGCGAGGCCGTGCGGGCGGTGTCGGACGC
GGTACGCCGCACCCGCGCCGGAATCGCCGACCCCGACCGGCCCACCGGCTCGTTCCTCTTCCTCGGCCCGACCGGTGTCG
GCAAGACGGAGCTCGCCAAGGCGCTCGCCGACTTCCTCTTCGACGACGAGCGGGCCATGGTCCGCATCGACATGAGCGAG
TACGGCGAGAAGCACAGCGTGGCGCGGCTCGTCGGCGCCCCGCCCGGATACGTCGGCTACGAGGAGGGCGGCCAGCTCAC
CGAGGCGGTCCGCCGCCGCCCGTACAGCGTCGTGCTGCTGGACGAGGTCGAGAAGGCCCACCCCGAGGTCTTCGACATCC
TGCTCCAGGTCCTCGACGACGGCCGGCTCACCGACGGGCAGGGCCGGACGGTGGACTTCCGCAACACCATCCTGATCCTG
ACCTCCAACCTCGGCAGCCAGTTCCTGGTCGATCCCCTGACCAAGCCCGAGGAGAAGAAGGAACGGGTCCTGGAGCTCGT
ACGGGCCTCGTTCAAGCCGGAGTTCCTCAACCGGCTGGACGACCTGGTGGTCTTCTCCGCCCTGTCCGGTGACGAGCTCG
CGCACATCGCGAAGCTCCAGATCGACCGGCTCGCCAAGCGGCTGGCCGACCGGCAGCTCACCCTCGACGTCACCCCGGCC
GCCCTGGCCTGGCTGGCCGAGGAGGGCAACGACCCGGCCTACGGGGCGCGGCCGCTGCGCCGCCTCATCCAGACGGCGAT
CGGCGACCGGCTGGCGAAGGAGATCCTCTCCGGCGAGGTGAAGGACGGGGACACCGTCCGGGTGGACCGGGTCGGTGACG
ACCTGCTCGTCGGCCCCGCGACCCCGGACGGCGCCGTGTAG

Domains

Predicted by InterProScan.

• AAA lid domain (AAA_lid_9) (344-446)

• ATPase family associated with various cellular activities (AAA) (AAA) (204-338)

• C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small) (768-848)

• AAA domain (Cdc48 subfamily) (AAA_2) (600-761)

• Clp amino terminal domain, pathogenicity island component (Clp_N) (18-69)

• Clp amino terminal domain, pathogenicity island component (Clp_N) (95-146)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpC	Bacillus subtilis subsp. subtilis str. 168	44.175	100	0.442
clpC	Lactococcus lactis subsp. lactis strain DGCC12653	42.689	97.921	0.418
clpC	Lactococcus lactis subsp. cremoris KW2	48.699	79.908	0.389
clpE	Streptococcus mutans UA159	47.478	77.829	0.37
clpE	Streptococcus pneumoniae R6	45.441	79.792	0.363
clpE	Streptococcus pneumoniae Rx1	45.441	79.792	0.363
clpE	Streptococcus pneumoniae D39	45.441	79.792	0.363
clpE	Streptococcus pneumoniae TIGR4	45.494	79.446	0.361