Detailed information NTG0672857

Bioinformatically predicted

Overview

• Name: braS
• Type: Regulator
• Locus tag: MUA38_RS13505
• Genome accession: NZ_CP094800
• Coordinates: 2708956..2709843 (-)
• Length: 295 a.a.
• NCBI ID: WP_000143420.1
• Uniprot ID: A0A2S6DP21
• Organism: Staphylococcus aureus strain IVB6158
• Function: promote expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 2703956..2714843

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
MUA38_RS13475 (MUA38_13455)	-	2703958..2704050 (+)	93	WP_010956583.1	hypothetical protein	-
MUA38_RS13480 (MUA38_13460)	-	2704158..2704655 (-)	498	WP_250426068.1	glutathione peroxidase	-
MUA38_RS13485 (MUA38_13465)	-	2704665..2704925 (-)	261	WP_078064828.1	hypothetical protein	-
MUA38_RS13490 (MUA38_13470)	-	2705307..2705420 (-)	114	WP_072491147.1	hypothetical protein	-
MUA38_RS13495 (MUA38_13475)	-	2706096..2708096 (-)	2001	WP_250426069.1	ABC transporter permease	-
MUA38_RS13500 (MUA38_13480)	-	2708093..2708848 (-)	756	WP_000923770.1	ABC transporter ATP-binding protein	-
MUA38_RS13505 (MUA38_13485)	braS	2708956..2709843 (-)	888	WP_000143420.1	nisin susceptibility-associated two-component system sensor histidine kinase NsaS	Regulator
MUA38_RS13510 (MUA38_13490)	braR	2709854..2710519 (-)	666	WP_000697877.1	nisin susceptibility-associated two-component system response regulator NsaR	Regulator
MUA38_RS13515 (MUA38_13495)	-	2710545..2710745 (-)	201	WP_000604725.1	hypothetical protein	-
MUA38_RS13520 (MUA38_13500)	-	2710943..2712367 (+)	1425	WP_000953759.1	alkaline phosphatase	-
MUA38_RS14005	-	2712427..2712528 (-)	102	WP_000731972.1	SE2200 family small protein	-
MUA38_RS13530 (MUA38_13510)	-	2712650..2713105 (-)	456	WP_000106185.1	MarR family winged helix-turn-helix transcriptional regulator	-
MUA38_RS13535 (MUA38_13515)	-	2713350..2714111 (-)	762	WP_000323448.1	alpha/beta hydrolase	-

Sequence

Protein

• Length: 295 a.a.
• Molecular weight: 34045.32 Da
• Isoelectric Point: 5.8962

>NTDB_id=672857 MUA38_RS13505 WP_000143420.1 2708956..2709843(-) (braS) [Staphylococcus aureus strain IVB6158]
MTFLKSITQEIAIVIVIFALFGLMFYLYHLPLEAYLLALGVILLLLLIFIGIKYLSFVKTISQQQQIENLENALYQLKNE
QIEYKNDVESYFLTWVHQMKTPITAAQLLLERDEPNVVNRVRQEVIQIDNYTSLALSYLKLLNETSDISVTKISINNIIR
PIIMKYSIQFIDQKTKIHYEPCHHEVLTDVRWTSLMIEQLINNALKYARGKDIWIEFDEQSNQLYVKDNGIGISEADLPK
IFDKGYSGYNGQRQSNSSGIGLFIVKQISTHTNHPVSVVSKQNEGTTFTIQFPDE

Nucleotide

• Length: 888 bp

>NTDB_id=672857 MUA38_RS13505 WP_000143420.1 2708956..2709843(-) (braS) [Staphylococcus aureus strain IVB6158]
ATGACCTTTCTTAAAAGTATTACTCAGGAAATAGCAATAGTCATAGTTATTTTTGCTTTATTTGGCTTAATGTTTTACCT
GTATCATTTGCCATTAGAAGCATATTTACTAGCACTTGGCGTTATTTTATTATTATTACTCATATTTATAGGTATTAAAT
ATTTAAGTTTTGTAAAAACTATAAGCCAACAACAACAAATTGAAAACTTAGAAAATGCGTTGTATCAGCTTAAAAATGAA
CAAATTGAATATAAAAATGATGTAGAGAGCTACTTTTTAACATGGGTACATCAAATGAAAACACCCATTACTGCAGCACA
ACTGTTACTTGAAAGAGATGAGCCTAATGTTGTGAATCGTGTTCGTCAAGAGGTTATTCAAATTGATAACTATACAAGTT
TAGCACTTAGTTATTTAAAGTTATTAAATGAAACTTCTGATATTTCTGTCACTAAAATTTCGATTAACAATATCATTCGC
CCAATTATTATGAAATATTCAATACAGTTTATTGATCAAAAAACAAAAATCCATTATGAACCTTGTCATCACGAAGTATT
AACTGACGTTAGATGGACCTCTTTAATGATAGAACAATTAATAAATAATGCACTTAAGTATGCGAGAGGTAAAGATATAT
GGATTGAATTTGATGAGCAATCCAATCAATTATACGTAAAAGATAATGGTATCGGTATTAGTGAAGCGGACTTGCCTAAA
ATATTTGATAAGGGCTATTCAGGTTATAATGGCCAGCGGCAAAGTAACTCAAGTGGGATTGGTTTATTTATCGTAAAACA
AATTTCAACTCACACAAACCATCCTGTTTCAGTCGTATCTAAACAAAATGAGGGTACAACATTTACGATTCAATTTCCAG
ATGAATAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (191-294)

3D structure

• AlphaFold DB: A0A2S6DP21

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
braS	Staphylococcus aureus N315	99.322	100	0.993