Detailed information NTG0672817

Bioinformatically predicted

Overview

• Name: braS
• Type: Regulator
• Locus tag: MUA85_RS13500
• Genome accession: NZ_CP094799
• Coordinates: 2708953..2709840 (-)
• Length: 295 a.a.
• NCBI ID: WP_000143420.1
• Uniprot ID: A0A2S6DP21
• Organism: Staphylococcus aureus strain IVB6159
• Function: promote expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 2703953..2714840

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
MUA85_RS13470 (MUA85_13450)	-	2703955..2704047 (+)	93	WP_010956583.1	hypothetical protein	-
MUA85_RS13475 (MUA85_13455)	-	2704155..2704652 (-)	498	WP_250426068.1	glutathione peroxidase	-
MUA85_RS13480 (MUA85_13460)	-	2704662..2704922 (-)	261	WP_078064828.1	hypothetical protein	-
MUA85_RS13485 (MUA85_13465)	-	2705304..2705417 (-)	114	WP_072491147.1	hypothetical protein	-
MUA85_RS13490 (MUA85_13470)	-	2706093..2708093 (-)	2001	WP_250426069.1	ABC transporter permease	-
MUA85_RS13495 (MUA85_13475)	-	2708090..2708845 (-)	756	WP_000923770.1	ABC transporter ATP-binding protein	-
MUA85_RS13500 (MUA85_13480)	braS	2708953..2709840 (-)	888	WP_000143420.1	nisin susceptibility-associated two-component system sensor histidine kinase NsaS	Regulator
MUA85_RS13505 (MUA85_13485)	braR	2709851..2710516 (-)	666	WP_000697877.1	nisin susceptibility-associated two-component system response regulator NsaR	Regulator
MUA85_RS13510 (MUA85_13490)	-	2710542..2710742 (-)	201	WP_000604725.1	hypothetical protein	-
MUA85_RS13515 (MUA85_13495)	-	2710940..2712364 (+)	1425	WP_000953759.1	alkaline phosphatase	-
MUA85_RS14010	-	2712424..2712525 (-)	102	WP_000731972.1	SE2200 family small protein	-
MUA85_RS13525 (MUA85_13505)	-	2712647..2713102 (-)	456	WP_000106185.1	MarR family winged helix-turn-helix transcriptional regulator	-
MUA85_RS13530 (MUA85_13510)	-	2713347..2714108 (-)	762	WP_000323448.1	alpha/beta hydrolase	-

Sequence

Protein

• Length: 295 a.a.
• Molecular weight: 34045.32 Da
• Isoelectric Point: 5.8962

>NTDB_id=672817 MUA85_RS13500 WP_000143420.1 2708953..2709840(-) (braS) [Staphylococcus aureus strain IVB6159]
MTFLKSITQEIAIVIVIFALFGLMFYLYHLPLEAYLLALGVILLLLLIFIGIKYLSFVKTISQQQQIENLENALYQLKNE
QIEYKNDVESYFLTWVHQMKTPITAAQLLLERDEPNVVNRVRQEVIQIDNYTSLALSYLKLLNETSDISVTKISINNIIR
PIIMKYSIQFIDQKTKIHYEPCHHEVLTDVRWTSLMIEQLINNALKYARGKDIWIEFDEQSNQLYVKDNGIGISEADLPK
IFDKGYSGYNGQRQSNSSGIGLFIVKQISTHTNHPVSVVSKQNEGTTFTIQFPDE

Nucleotide

• Length: 888 bp

>NTDB_id=672817 MUA85_RS13500 WP_000143420.1 2708953..2709840(-) (braS) [Staphylococcus aureus strain IVB6159]
ATGACCTTTCTTAAAAGTATTACTCAGGAAATAGCAATAGTCATAGTTATTTTTGCTTTATTTGGCTTAATGTTTTACCT
GTATCATTTGCCATTAGAAGCATATTTACTAGCACTTGGCGTTATTTTATTATTATTACTCATATTTATAGGTATTAAAT
ATTTAAGTTTTGTAAAAACTATAAGCCAACAACAACAAATTGAAAACTTAGAAAATGCGTTGTATCAGCTTAAAAATGAA
CAAATTGAATATAAAAATGATGTAGAGAGCTACTTTTTAACATGGGTACATCAAATGAAAACACCCATTACTGCAGCACA
ACTGTTACTTGAAAGAGATGAGCCTAATGTTGTGAATCGTGTTCGTCAAGAGGTTATTCAAATTGATAACTATACAAGTT
TAGCACTTAGTTATTTAAAGTTATTAAATGAAACTTCTGATATTTCTGTCACTAAAATTTCGATTAACAATATCATTCGC
CCAATTATTATGAAATATTCAATACAGTTTATTGATCAAAAAACAAAAATCCATTATGAACCTTGTCATCACGAAGTATT
AACTGACGTTAGATGGACCTCTTTAATGATAGAACAATTAATAAATAATGCACTTAAGTATGCGAGAGGTAAAGATATAT
GGATTGAATTTGATGAGCAATCCAATCAATTATACGTAAAAGATAATGGTATCGGTATTAGTGAAGCGGACTTGCCTAAA
ATATTTGATAAGGGCTATTCAGGTTATAATGGCCAGCGGCAAAGTAACTCAAGTGGGATTGGTTTATTTATCGTAAAACA
AATTTCAACTCACACAAACCATCCTGTTTCAGTCGTATCTAAACAAAATGAGGGTACAACATTTACGATTCAATTTCCAG
ATGAATAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (191-294)

3D structure

• AlphaFold DB: A0A2S6DP21

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
braS	Staphylococcus aureus N315	99.322	100	0.993