Detailed information NTG0672736

Bioinformatically predicted

Overview

• Name: braS
• Type: Regulator
• Locus tag: MUA75_RS13055
• Genome accession: NZ_CP094795
• Coordinates: 2643238..2644125 (-)
• Length: 295 a.a.
• NCBI ID: WP_000143420.1
• Uniprot ID: A0A2S6DP21
• Organism: Staphylococcus aureus strain IVB6164
• Function: promote expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 2638238..2649125

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
MUA75_RS13025 (MUA75_13015)	-	2638241..2638333 (+)	93	WP_010956583.1	hypothetical protein	-
MUA75_RS13030 (MUA75_13020)	-	2638441..2638938 (-)	498	WP_001065267.1	glutathione peroxidase	-
MUA75_RS13035 (MUA75_13025)	-	2638948..2639208 (-)	261	WP_014532715.1	hypothetical protein	-
MUA75_RS13040 (MUA75_13030)	-	2639590..2639703 (-)	114	WP_072357681.1	hypothetical protein	-
MUA75_RS13045 (MUA75_13035)	-	2640378..2642378 (-)	2001	WP_262629868.1	ABC transporter permease	-
MUA75_RS13050 (MUA75_13040)	-	2642375..2643130 (-)	756	WP_262629869.1	ABC transporter ATP-binding protein	-
MUA75_RS13055 (MUA75_13045)	braS	2643238..2644125 (-)	888	WP_000143420.1	nisin susceptibility-associated two-component system sensor histidine kinase NsaS	Regulator
MUA75_RS13060 (MUA75_13050)	braR	2644136..2644801 (-)	666	WP_000697877.1	nisin susceptibility-associated two-component system response regulator NsaR	Regulator
MUA75_RS13065 (MUA75_13055)	-	2644827..2645027 (-)	201	WP_000604727.1	hypothetical protein	-
MUA75_RS13070 (MUA75_13060)	-	2645225..2646649 (+)	1425	WP_000948997.1	alkaline phosphatase	-
MUA75_RS13670	-	2646709..2646810 (-)	102	WP_000731972.1	SE2200 family small protein	-
MUA75_RS13080 (MUA75_13070)	-	2646932..2647387 (-)	456	WP_000106185.1	MarR family winged helix-turn-helix transcriptional regulator	-
MUA75_RS13085 (MUA75_13075)	-	2647632..2648393 (-)	762	WP_262629871.1	alpha/beta hydrolase	-

Sequence

Protein

• Length: 295 a.a.
• Molecular weight: 34045.32 Da
• Isoelectric Point: 5.8962

>NTDB_id=672736 MUA75_RS13055 WP_000143420.1 2643238..2644125(-) (braS) [Staphylococcus aureus strain IVB6164]
MTFLKSITQEIAIVIVIFALFGLMFYLYHLPLEAYLLALGVILLLLLIFIGIKYLSFVKTISQQQQIENLENALYQLKNE
QIEYKNDVESYFLTWVHQMKTPITAAQLLLERDEPNVVNRVRQEVIQIDNYTSLALSYLKLLNETSDISVTKISINNIIR
PIIMKYSIQFIDQKTKIHYEPCHHEVLTDVRWTSLMIEQLINNALKYARGKDIWIEFDEQSNQLYVKDNGIGISEADLPK
IFDKGYSGYNGQRQSNSSGIGLFIVKQISTHTNHPVSVVSKQNEGTTFTIQFPDE

Nucleotide

• Length: 888 bp

>NTDB_id=672736 MUA75_RS13055 WP_000143420.1 2643238..2644125(-) (braS) [Staphylococcus aureus strain IVB6164]
ATGACCTTTCTTAAAAGTATTACTCAGGAAATAGCAATAGTCATAGTTATTTTTGCTTTATTTGGCTTAATGTTTTACCT
GTATCATTTGCCATTAGAAGCATATTTACTAGCACTTGGCGTTATTTTATTATTATTACTCATATTTATAGGTATTAAAT
ATTTAAGTTTTGTAAAAACTATAAGCCAACAACAACAAATTGAAAACTTAGAAAATGCGTTGTATCAGCTTAAAAATGAA
CAAATTGAATATAAAAATGATGTAGAGAGCTACTTTTTAACATGGGTACATCAAATGAAAACACCCATTACTGCAGCACA
ACTGTTACTTGAAAGAGATGAGCCTAATGTTGTGAATCGTGTTCGTCAAGAGGTTATTCAAATTGATAACTATACAAGTT
TAGCACTTAGTTATTTAAAGTTATTAAATGAAACTTCTGATATTTCTGTCACTAAAATTTCGATTAACAATATCATTCGC
CCAATTATTATGAAATATTCAATACAGTTTATTGATCAAAAAACAAAAATCCATTATGAACCTTGTCATCACGAAGTATT
AACTGACGTTAGATGGACCTCTTTAATGATAGAACAATTAATAAATAATGCACTTAAGTATGCGAGAGGTAAAGATATAT
GGATTGAATTTGATGAGCAATCCAATCAATTATACGTAAAAGATAATGGTATCGGTATTAGTGAAGCGGACTTGCCTAAA
ATATTTGATAAGGGCTATTCAGGTTATAATGGCCAGCGGCAAAGTAACTCAAGTGGGATTGGTTTATTTATCGTAAAACA
AATTTCAACTCACACAAACCATCCTGTTTCAGTCGTATCTAAACAAAATGAGGGTACAACATTTACGATTCAATTTCCAG
ATGAATAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (191-294)

3D structure

• AlphaFold DB: A0A2S6DP21

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
braS	Staphylococcus aureus N315	99.322	100	0.993