Detailed information    

insolico Bioinformatically predicted

Overview

Name   agrA   Type   Regulator
Locus tag   MUA93_RS10220 Genome accession   NZ_CP094793
Coordinates   2077458..2078174 (+) Length   238 a.a.
NCBI ID   WP_000688492.1    Uniprot ID   A0A7U7IEW1
Organism   Staphylococcus aureus strain IVB6165     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 2072458..2083174
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  MUA93_RS10190 (MUA93_10180) - 2072674..2073300 (+) 627 WP_000522384.1 nitroreductase family protein -
  MUA93_RS10195 (MUA93_10185) - 2073662..2074447 (+) 786 WP_000867945.1 carbon-nitrogen family hydrolase -
  MUA93_RS10200 (MUA93_10190) hld 2075046..2075126 (-) 81 WP_000046022.1 delta-hemolysin -
  MUA93_RS10205 (MUA93_10195) - 2075417..2075980 (+) 564 WP_001105699.1 accessory gene regulator AgrB -
  MUA93_RS10210 (MUA93_10200) agrD 2075983..2076126 (+) 144 WP_001094921.1 cyclic lactone autoinducer peptide AgrD -
  MUA93_RS10215 (MUA93_10205) agrC 2076156..2077439 (+) 1284 WP_000447894.1 quorum-sensing sensor histidine kinase AgrC -
  MUA93_RS10220 (MUA93_10210) agrA 2077458..2078174 (+) 717 WP_000688492.1 quorum-sensing response regulator AgrA Regulator
  MUA93_RS10225 (MUA93_10215) - 2078246..2078353 (+) 108 WP_001803734.1 hypothetical protein -
  MUA93_RS10230 (MUA93_10220) - 2078541..2079500 (-) 960 WP_262529043.1 carbohydrate kinase family protein -
  MUA93_RS10235 (MUA93_10225) - 2079497..2080981 (-) 1485 WP_262543003.1 sucrose-6-phosphate hydrolase -
  MUA93_RS10240 (MUA93_10230) - 2081130..2082080 (-) 951 WP_000790321.1 LacI family DNA-binding transcriptional regulator -

Sequence

Protein


Download         Length: 238 a.a.        Molecular weight: 27905.90 Da        Isoelectric Point: 6.0927

>NTDB_id=672692 MUA93_RS10220 WP_000688492.1 2077458..2078174(+) (agrA) [Staphylococcus aureus strain IVB6165]
MKIFICEDDPKQRENMVTIIKNYIMIEEKPMEIALATDNPYEVLEQAKNMNDIGCYFLDIQLSTDINGIKLGSEIRKHDP
VGNIIFVTSHSELTYLTFVYKVAAMDFIFKDDPAELRTRIIDCLETAHTRLQLLSKDNSVETIELKRGSNSVYVQYDDIM
FFESSTKSHRLIAHLDNRQIEFYGNLKELSQLDDRFFRCHNSFVVNRHNIESIDSKERIVYFKNKEHCYASVRNVKKI

Nucleotide


Download         Length: 717 bp        

>NTDB_id=672692 MUA93_RS10220 WP_000688492.1 2077458..2078174(+) (agrA) [Staphylococcus aureus strain IVB6165]
ATGAAAATTTTCATTTGCGAAGACGATCCAAAACAAAGAGAAAACATGGTTACCATTATTAAAAATTATATAATGATAGA
AGAAAAGCCTATGGAAATTGCCCTCGCAACTGATAATCCTTATGAGGTGCTTGAGCAAGCTAAAAATATGAATGACATAG
GCTGTTACTTTTTAGATATTCAACTTTCAACTGATATTAATGGTATCAAATTAGGCAGTGAAATTCGTAAGCATGATCCA
GTTGGTAACATTATATTTGTTACGAGTCACAGTGAACTTACCTATTTAACGTTTGTCTACAAAGTTGCAGCGATGGATTT
TATTTTTAAAGATGATCCAGCTGAATTAAGAACTCGAATTATAGACTGTTTAGAAACTGCACATACACGCTTACAATTGT
TGTCTAAAGATAATAGCGTTGAAACGATTGAATTAAAACGTGGCAGTAATTCAGTGTATGTTCAATATGATGATATTATG
TTTTTTGAATCATCAACAAAATCTCACAGACTCATTGCCCATTTAGATAACCGTCAAATTGAATTTTATGGTAATTTAAA
AGAACTGAGTCAATTAGATGATCGTTTCTTTAGATGTCATAATAGCTTTGTCGTCAATCGCCATAACATTGAATCTATAG
ATTCGAAAGAGCGAATTGTCTATTTTAAAAATAAAGAACACTGCTATGCATCGGTGAGAAACGTTAAAAAAATATAA

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(3-120)

LytTr DNA-binding domain (LytTR)

(151-237)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A7U7IEW1

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  agrA Staphylococcus aureus N315

100

100

1