Detailed information    

insolico Bioinformatically predicted

Overview

Name   clpE   Type   Regulator
Locus tag   SITYG_RS07405 Genome accession   NZ_AP014880
Coordinates   1462829..1465096 (+) Length   755 a.a.
NCBI ID   WP_096363053.1    Uniprot ID   A0AAD1FKB5
Organism   Streptococcus intermedius strain TYG1620     
Function   degradation of ComX (predicted from homology)   
Competence regulation

Genomic Context

Location: 1457829..1470096
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SITYG_RS07375 - 1458368..1458661 (-) 294 WP_231870222.1 hypothetical protein -
  SITYG_RS07380 (SITYG_14620) - 1458756..1459298 (-) 543 WP_003077029.1 ClbS/DfsB family four-helix bundle protein -
  SITYG_RS07385 (SITYG_14630) - 1459430..1459564 (-) 135 WP_009569163.1 FeoB-associated Cys-rich membrane protein -
  SITYG_RS07390 (SITYG_14640) feoB 1459573..1461717 (-) 2145 WP_096363052.1 ferrous iron transport protein B -
  SITYG_RS07395 (SITYG_14650) - 1461714..1462190 (-) 477 WP_048786209.1 FeoA family protein -
  SITYG_RS07400 (SITYG_14660) - 1462359..1462589 (-) 231 WP_003023686.1 DUF1797 family protein -
  SITYG_RS07405 (SITYG_14670) clpE 1462829..1465096 (+) 2268 WP_096363053.1 ATP-dependent Clp protease ATP-binding subunit Regulator
  SITYG_RS07410 (SITYG_14680) - 1465143..1465748 (-) 606 WP_003071947.1 GyrI-like domain-containing protein -
  SITYG_RS07415 (SITYG_14690) - 1465808..1466701 (-) 894 WP_096363054.1 helix-turn-helix transcriptional regulator -
  SITYG_RS07420 (SITYG_14700) - 1466858..1467307 (+) 450 WP_096363055.1 NUDIX hydrolase -
  SITYG_RS07425 (SITYG_14710) - 1467371..1467670 (+) 300 WP_003071940.1 DUF1827 family protein -
  SITYG_RS07430 (SITYG_14720) - 1467744..1469798 (-) 2055 WP_096363056.1 cation:proton antiporter -
  SITYG_RS07435 (SITYG_14730) - 1469810..1470064 (-) 255 WP_096363057.1 hypothetical protein -

Sequence

Protein


Download         Length: 755 a.a.        Molecular weight: 84375.52 Da        Isoelectric Point: 5.1073

>NTDB_id=67266 SITYG_RS07405 WP_096363053.1 1462829..1465096(+) (clpE) [Streptococcus intermedius strain TYG1620]
MLCQNCKINESTIHLYTNVNGKQHQVDLCQNCYQIMKTDPNNALFRGMTNMNNQNNLDPFDDFFSNIGNFQNHQEPQTPP
TQSGGGYGNGGYGSNQGNSTRQQASQQPKGLLEEFGINVTEFARRGEIDPVIGRDEEIVRVIEILNRRTKNNPVLIGEPG
VGKTAVVEGLAQKIVDGDVPHKLQDKEVIRLDVVSLVQGTGIRGQFEERMQKLMNEIRSRQDVILFIDEIHEIVGAGSAG
DGNMDAGNILKPALARGELQLVGATTLNEYRIIEKDAALERRMQPVKVDEPTVEETITILKGIQKKYEDYHHVKYTDDAI
EAAAVLSNRYIQDRFLPDKAIDLLDEAGSKMNLTLNFVDPKVIDQRLVEAENLKAQATRDEDFEKAAYFRDQIAKYKEMQ
QNKMADQDTPLISEKTIEHIIEQKTNIPVGDLKEKEQSQLISLADDLKAHVIGQDDAVDKIAKAIRRNRVGLGTPNRPIG
SFLFVGPTGVGKTELSKQLAIELFGSADSMIRFDMSEYMEKHSVAKLVGAPPGYVGYEEAGQLTERVRRNPYSLILLDEI
EKAHPDVMHMFLQVLDDGRLTDGQGRTVSFKDTIIIMTSNAGTGKVEANVGFGAAREGRTNSVIGELGNFFSPEFINRFD
GIIEFKSLSKENLLQIVDLMLKDVNERLATNDIYLDVTDKVKEKLVNLGYDPKMGARPLRRTIQDHIEDAITDYYLEHPS
DKELKAIMTSNGKIVIKPAKKSENKSKTTIDNNAN

Nucleotide


Download         Length: 2268 bp        

>NTDB_id=67266 SITYG_RS07405 WP_096363053.1 1462829..1465096(+) (clpE) [Streptococcus intermedius strain TYG1620]
ATGCTTTGTCAAAACTGTAAAATAAATGAATCTACCATTCATCTTTACACAAATGTTAATGGGAAACAACATCAAGTTGA
CCTCTGTCAAAATTGTTATCAAATCATGAAAACGGATCCAAATAATGCCTTATTTCGTGGCATGACCAATATGAATAATC
AAAACAACCTAGATCCATTTGATGATTTCTTTAGCAATATAGGGAATTTTCAAAATCATCAAGAACCGCAGACTCCTCCT
ACTCAATCAGGTGGTGGATATGGCAATGGAGGCTATGGCTCCAATCAAGGCAATAGTACACGCCAACAAGCATCACAGCA
ACCTAAAGGTCTCCTAGAGGAATTCGGTATCAATGTGACTGAATTTGCTCGGCGTGGTGAAATTGACCCCGTGATTGGTC
GTGATGAGGAAATTGTTCGTGTTATTGAAATCCTCAATCGTAGAACGAAGAACAACCCTGTCCTCATCGGAGAGCCCGGT
GTCGGTAAAACAGCAGTTGTCGAAGGCTTGGCTCAGAAAATTGTAGACGGTGATGTGCCACATAAACTCCAAGACAAAGA
AGTTATCCGCTTAGATGTCGTTAGCTTGGTTCAAGGAACTGGTATCCGTGGTCAATTTGAAGAACGAATGCAAAAACTCA
TGAACGAAATTCGCTCTCGTCAGGATGTGATATTATTCATTGATGAAATTCACGAAATTGTTGGAGCTGGTTCTGCTGGT
GATGGAAATATGGATGCTGGAAACATTCTAAAACCAGCACTTGCTCGCGGTGAACTCCAATTAGTTGGTGCCACAACTCT
CAATGAATACCGGATTATCGAAAAAGATGCTGCACTGGAACGCCGTATGCAGCCTGTAAAAGTTGATGAACCAACAGTTG
AAGAAACGATCACTATCCTCAAAGGTATTCAAAAGAAATACGAAGACTATCACCACGTCAAATACACCGACGATGCCATT
GAAGCAGCAGCTGTCTTGTCCAATCGGTATATCCAAGATCGCTTCTTGCCTGATAAGGCCATTGACTTGTTAGATGAAGC
AGGCTCTAAGATGAATCTGACACTTAACTTTGTCGATCCAAAAGTCATTGATCAACGATTGGTAGAAGCTGAAAACCTCA
AGGCACAAGCTACTCGCGATGAAGATTTTGAAAAAGCTGCTTATTTCCGTGACCAAATTGCCAAATACAAAGAAATGCAG
CAAAATAAAATGGCTGATCAAGATACGCCTCTTATCAGTGAAAAAACCATTGAACATATCATTGAGCAAAAGACAAATAT
TCCAGTTGGCGACTTGAAAGAAAAGGAACAATCACAATTGATTAGTCTGGCTGATGATTTGAAAGCTCATGTCATTGGGC
AAGATGATGCTGTTGATAAAATTGCGAAGGCCATTCGCCGTAATCGAGTTGGACTAGGTACACCAAACCGACCAATTGGT
TCTTTCCTTTTTGTTGGGCCAACCGGTGTCGGCAAAACAGAACTTTCTAAACAATTAGCGATTGAGCTCTTTGGTTCAGC
TGACAGCATGATTCGCTTTGATATGAGTGAGTATATGGAAAAACATAGCGTAGCAAAACTCGTCGGAGCCCCTCCAGGTT
ACGTTGGCTACGAAGAGGCTGGGCAATTAACAGAACGCGTACGTCGTAATCCTTATTCTCTCATTTTACTTGATGAAATA
GAAAAAGCTCACCCAGATGTCATGCACATGTTCTTGCAAGTACTGGATGACGGACGTCTGACAGATGGACAAGGTCGGAC
AGTCAGTTTCAAAGATACGATTATCATTATGACTTCCAACGCCGGTACTGGAAAAGTTGAAGCAAACGTCGGATTCGGTG
CAGCGCGTGAAGGACGAACCAATTCTGTTATCGGTGAATTAGGGAACTTCTTCAGTCCAGAATTTATAAACCGTTTTGAT
GGTATTATTGAGTTCAAATCTCTTAGCAAAGAAAATCTCCTACAAATCGTAGATTTGATGCTTAAAGATGTCAATGAACG
GCTTGCCACGAATGACATTTACCTAGATGTAACAGATAAAGTCAAGGAAAAATTAGTTAATCTTGGTTACGATCCGAAAA
TGGGAGCTCGTCCACTTCGTCGGACAATCCAAGATCACATTGAGGATGCTATCACTGACTACTATCTTGAACATCCAAGC
GACAAAGAGCTCAAAGCTATCATGACAAGTAATGGTAAGATTGTCATCAAACCAGCTAAAAAATCTGAGAATAAATCCAA
GACAACAATAGATAACAATGCTAATTAG

Domains

Predicted by InterproScan.

ATPase family associated with various cellular activities (AAA) (AAA)

(154-273)

C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small)

(648-722)

AAA lid domain (AAA_lid_9)

(292-389)

AAA domain (Cdc48 subfamily) (AAA_2)

(477-640)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  clpE Streptococcus pneumoniae Rx1

86.497

99.073

0.857
  clpE Streptococcus pneumoniae D39

86.497

99.073

0.857
  clpE Streptococcus pneumoniae R6

86.497

99.073

0.857
  clpE Streptococcus pneumoniae TIGR4

86.497

99.073

0.857
  clpE Streptococcus mutans UA159

84.503

100

0.845
  clpC Lactococcus lactis subsp. cremoris KW2

76.79

99.868

0.767
  clpC Bacillus subtilis subsp. subtilis str. 168

51.791

88.742

0.46
  clpC Lactococcus lactis subsp. lactis strain DGCC12653

47.546

86.358

0.411
  clpC Streptococcus pneumoniae Rx1

48.548

82.119

0.399
  clpC Streptococcus pneumoniae D39

48.548

82.119

0.399
  clpC Streptococcus pneumoniae TIGR4

48.387

82.119

0.397
  clpC Streptococcus thermophilus LMD-9

47.352

82.517

0.391
  clpC Streptococcus thermophilus LMG 18311

47.276

82.649

0.391
  clpC Streptococcus mutans UA159

47.496

81.987

0.389

Multiple sequence alignment