Detailed information NTG0672566

Bioinformatically predicted

Overview

• Name: braS
• Type: Regulator
• Locus tag: MUA13_RS13155
• Genome accession: NZ_CP094787
• Coordinates: 2657761..2658648 (-)
• Length: 295 a.a.
• NCBI ID: WP_000143419.1
• Uniprot ID: A0A266CLT2
• Organism: Staphylococcus aureus strain IVB6168
• Function: promote expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 2652761..2663648

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
MUA13_RS13125 (MUA13_13115)	-	2652784..2652872 (+)	89	Protein_2550	hypothetical protein	-
MUA13_RS13130 (MUA13_13120)	-	2652980..2653477 (-)	498	Protein_2551	glutathione peroxidase	-
MUA13_RS13135 (MUA13_13125)	-	2653487..2653747 (-)	261	WP_001789910.1	hypothetical protein	-
MUA13_RS13140 (MUA13_13130)	-	2654129..2654242 (-)	114	WP_011447078.1	hypothetical protein	-
MUA13_RS13145 (MUA13_13135)	-	2654901..2656901 (-)	2001	WP_252570722.1	ABC transporter permease	-
MUA13_RS13150 (MUA13_13140)	-	2656898..2657653 (-)	756	WP_000923760.1	ABC transporter ATP-binding protein	-
MUA13_RS13155 (MUA13_13145)	braS	2657761..2658648 (-)	888	WP_000143419.1	nisin susceptibility-associated two-component system sensor histidine kinase NsaS	Regulator
MUA13_RS13160 (MUA13_13150)	braR	2658659..2659324 (-)	666	WP_000697886.1	nisin susceptibility-associated two-component system response regulator NsaR	Regulator
MUA13_RS13165 (MUA13_13155)	-	2659350..2659550 (-)	201	WP_000604727.1	hypothetical protein	-
MUA13_RS13170 (MUA13_13160)	-	2659748..2661163 (+)	1416	WP_252570723.1	alkaline phosphatase	-
MUA13_RS13895	-	2661223..2661324 (-)	102	WP_000731976.1	SE2200 family small protein	-
MUA13_RS13180 (MUA13_13170)	-	2661446..2661901 (-)	456	WP_000106185.1	MarR family winged helix-turn-helix transcriptional regulator	-
MUA13_RS13185 (MUA13_13175)	-	2662146..2662907 (-)	762	WP_252570724.1	alpha/beta hydrolase family protein	-

Sequence

Protein

• Length: 295 a.a.
• Molecular weight: 34019.28 Da
• Isoelectric Point: 6.0874

>NTDB_id=672566 MUA13_RS13155 WP_000143419.1 2657761..2658648(-) (braS) [Staphylococcus aureus strain IVB6168]
MTFLKSITQEIAIVIVIFALFGLMFYLYHLPLEAYLLALGVILLLLLIFIGIKYLSFVKTISQQQQIENLENALYQLKNE
QIEYKNDVESYFLTWVHQMKTPITAAQLLLERDEPNVVNRVRQEVIQIDNYTSLALSYLKLLNETSDISVTKISINNIIR
PIIMKYSIQFIDQKTKIHYEPCHHEVLTDVRWTSLMIEQLINNALKYARGKDIWIEFDEQSNQLHVKDNGIGISEADLPK
IFDKGYSGYNGQRQSNSSGIGLFIVKQISTHTNHPVSVVSKQNEGTTFTIQFPDE

Nucleotide

• Length: 888 bp

>NTDB_id=672566 MUA13_RS13155 WP_000143419.1 2657761..2658648(-) (braS) [Staphylococcus aureus strain IVB6168]
ATGACCTTTCTTAAAAGTATTACTCAGGAAATAGCAATAGTCATAGTTATTTTTGCTTTGTTTGGCTTAATGTTTTACCT
GTATCATTTGCCATTAGAAGCATATTTACTAGCACTTGGCGTTATTTTATTATTATTACTCATATTCATAGGTATTAAAT
ATTTAAGTTTTGTAAAAACTATAAGCCAACAACAACAAATTGAAAACTTAGAAAATGCGTTGTATCAGCTTAAAAATGAA
CAAATTGAATATAAAAATGATGTAGAGAGCTACTTTTTAACATGGGTACATCAAATGAAAACACCCATTACTGCAGCACA
ACTGTTACTTGAAAGAGATGAGCCTAATGTTGTTAATCGTGTTCGTCAAGAGGTTATTCAAATTGATAACTATACAAGTT
TAGCACTTAGTTATTTAAAGTTATTAAATGAAACTTCTGATATTTCTGTCACTAAAATTTCGATTAATAATATCATTCGC
CCAATTATTATGAAATATTCAATACAGTTTATTGATCAAAAAACAAAAATCCATTATGAACCTTGTCATCACGAAGTATT
AACTGACGTTAGATGGACCTCTTTAATGATAGAACAATTAATAAATAATGCACTTAAGTATGCGAGAGGTAAAGATATAT
GGATTGAATTTGATGAGCAATCCAATCAATTACACGTAAAAGATAATGGTATCGGTATTAGTGAAGCGGACTTGCCTAAA
ATATTTGATAAGGGCTATTCAGGTTATAATGGCCAGCGCCAAAGTAACTCAAGTGGGATTGGTTTATTTATCGTAAAACA
AATTTCAACACACACAAACCATCCTGTTTCAGTCGTATCTAAACAAAATGAGGGTACAACATTTACGATTCAATTTCCAG
ATGAATAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (191-294)

3D structure

• AlphaFold DB: A0A266CLT2

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
braS	Staphylococcus aureus N315	99.661	100	0.997