Detailed information    

insolico Bioinformatically predicted

Overview

Name   agrA   Type   Regulator
Locus tag   MUA13_RS10090 Genome accession   NZ_CP094787
Coordinates   2053432..2054148 (+) Length   238 a.a.
NCBI ID   WP_000688492.1    Uniprot ID   A0A7U7IEW1
Organism   Staphylococcus aureus strain IVB6168     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 2048432..2059148
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  MUA13_RS10060 (MUA13_10050) - 2048650..2049276 (+) 627 WP_000522384.1 nitroreductase family protein -
  MUA13_RS10065 (MUA13_10055) - 2049637..2050422 (+) 786 WP_197805571.1 carbon-nitrogen family hydrolase -
  MUA13_RS13875 (MUA13_10060) hld 2051019..2051099 (-) 81 WP_000046022.1 delta-hemolysin -
  MUA13_RS10075 (MUA13_10065) - 2051389..2051952 (+) 564 WP_001105705.1 accessory gene regulator AgrB -
  MUA13_RS10080 (MUA13_10070) agrD 2051956..2052096 (+) 141 WP_000735197.1 cyclic lactone autoinducer peptide AgrD -
  MUA13_RS10085 (MUA13_10075) agrC 2052121..2053413 (+) 1293 WP_000387809.1 quorum-sensing sensor histidine kinase AgrC -
  MUA13_RS10090 (MUA13_10080) agrA 2053432..2054148 (+) 717 WP_000688492.1 quorum-sensing response regulator AgrA Regulator
  MUA13_RS10095 (MUA13_10085) - 2054220..2054329 (+) 110 Protein_1955 hypothetical protein -
  MUA13_RS10100 (MUA13_10090) - 2054517..2055476 (-) 960 WP_252570576.1 carbohydrate kinase -
  MUA13_RS10105 (MUA13_10095) - 2055473..2056957 (-) 1485 WP_252570578.1 sucrose-6-phosphate hydrolase -
  MUA13_RS10110 (MUA13_10100) - 2057106..2058056 (-) 951 WP_000790330.1 LacI family DNA-binding transcriptional regulator -

Sequence

Protein


Download         Length: 238 a.a.        Molecular weight: 27905.90 Da        Isoelectric Point: 6.0927

>NTDB_id=672562 MUA13_RS10090 WP_000688492.1 2053432..2054148(+) (agrA) [Staphylococcus aureus strain IVB6168]
MKIFICEDDPKQRENMVTIIKNYIMIEEKPMEIALATDNPYEVLEQAKNMNDIGCYFLDIQLSTDINGIKLGSEIRKHDP
VGNIIFVTSHSELTYLTFVYKVAAMDFIFKDDPAELRTRIIDCLETAHTRLQLLSKDNSVETIELKRGSNSVYVQYDDIM
FFESSTKSHRLIAHLDNRQIEFYGNLKELSQLDDRFFRCHNSFVVNRHNIESIDSKERIVYFKNKEHCYASVRNVKKI

Nucleotide


Download         Length: 717 bp        

>NTDB_id=672562 MUA13_RS10090 WP_000688492.1 2053432..2054148(+) (agrA) [Staphylococcus aureus strain IVB6168]
ATGAAAATTTTCATTTGCGAAGACGATCCAAAACAAAGAGAAAACATGGTTACCATTATTAAAAATTATATAATGATAGA
AGAAAAGCCTATGGAAATTGCCCTCGCAACTGATAATCCTTATGAGGTGCTTGAGCAAGCTAAAAATATGAATGACATAG
GCTGTTACTTTTTAGATATTCAACTTTCAACTGATATTAATGGTATCAAATTAGGCAGTGAAATTCGTAAGCATGACCCA
GTTGGTAACATTATTTTCGTTACGAGTCACAGCGAACTTACCTATTTAACGTTTGTCTACAAAGTTGCAGCGATGGATTT
TATTTTTAAAGATGATCCAGCTGAATTAAGAACTCGAATTATAGACTGTTTAGAAACTGCACATACACGCTTACAATTGT
TGTCTAAAGATAATAGCGTTGAAACGATTGAATTAAAACGTGGCAGTAATTCAGTGTATGTTCAATATGATGATATTATG
TTTTTTGAATCATCAACAAAATCTCACAGACTCATTGCCCATTTAGATAACCGTCAAATTGAATTTTATGGTAATTTAAA
AGAACTGAGTCAATTAGATGATCGTTTCTTTAGATGTCATAATAGCTTTGTCGTCAATCGCCATAATATTGAATCTATAG
ATTCGAAAGAGCGAATTGTCTATTTTAAAAATAAAGAACACTGCTATGCATCGGTGAGAAACGTTAAAAAAATATAA

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(3-120)

LytTr DNA-binding domain (LytTR)

(151-237)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A7U7IEW1

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  agrA Staphylococcus aureus N315

100

100

1