Detailed information NTG0672561

Bioinformatically predicted

Overview

• Name: vraS
• Type: Regulator
• Locus tag: MUA13_RS09610
• Genome accession: NZ_CP094787
• Coordinates: 1964262..1965305 (-)
• Length: 347 a.a.
• NCBI ID: WP_001017131.1
• Uniprot ID: A0A0D1IMN4
• Organism: Staphylococcus aureus strain IVB6168
• Function: repress expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 1959262..1970305

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
MUA13_RS09580 (MUA13_09570)	-	1959684..1960940 (-)	1257	WP_252570181.1	aminopeptidase	-
MUA13_RS09585 (MUA13_09575)	-	1960943..1961143 (-)	201	WP_000180460.1	DUF1128 family protein	-
MUA13_RS09590 (MUA13_09580)	-	1961290..1961754 (+)	465	WP_000228666.1	low molecular weight protein-tyrosine-phosphatase	-
MUA13_RS09595 (MUA13_09585)	-	1961761..1962036 (+)	276	WP_061650057.1	YtxH domain-containing protein	-
MUA13_RS09600 (MUA13_09590)	-	1962314..1963531 (+)	1218	WP_000037075.1	YihY/virulence factor BrkB family protein	-
MUA13_RS09605 (MUA13_09595)	vraR	1963643..1964272 (-)	630	WP_000153535.1	two-component system response regulator VraR	Regulator
MUA13_RS09610 (MUA13_09600)	vraS	1964262..1965305 (-)	1044	WP_001017131.1	sensor histidine kinase	Regulator
MUA13_RS09615 (MUA13_09605)	liaF	1965302..1966003 (-)	702	WP_000149064.1	cell wall-active antibiotics response protein LiaF	-
MUA13_RS09620 (MUA13_09610)	-	1966018..1966404 (-)	387	WP_001110179.1	hypothetical protein	-
MUA13_RS09625 (MUA13_09615)	map	1966621..1967379 (-)	759	WP_000636142.1	type I methionyl aminopeptidase	-
MUA13_RS09630 (MUA13_09620)	-	1967853..1968839 (+)	987	WP_262522385.1	aromatic acid exporter family protein	-
MUA13_RS09635 (MUA13_09625)	-	1969270..1969683 (-)	414	WP_252569368.1	hypothetical protein	-
MUA13_RS09640 (MUA13_09630)	-	1969712..1969820 (-)	109	Protein_1863	hypothetical protein	-

Sequence

Protein

• Length: 347 a.a.
• Molecular weight: 40044.52 Da
• Isoelectric Point: 6.0577

>NTDB_id=672561 MUA13_RS09610 WP_001017131.1 1964262..1965305(-) (vraS) [Staphylococcus aureus strain IVB6168]
MNHYIRTIGSMLILVYSMLAAFLFIDKVFVNIIYFQGMFYTQIFGIPVFLFLNLIIILLCIIVGSVLAYKINQQNDWIKT
QIERSMEGETVGINDQNIEIYSETLDLYHTLVPLNQELHKLRLKTQNLTNENYNINDVKVKKIIEDERQRLARELHDSVS
QQLFAASMMLSAIKETKLEPPLDQQIPILEKMVQDSQLEMRALLLHLRPLGLKDKSLGEGIKDLVIDLQKKVPMKVVHEI
QDFKVPKGIEDHLFRITQEAISNTLRHSNGTKVTVELFNKDDYLLLRIQDNGKGFNVDEKLEQSYGLKNMRERALEIGAT
FHIVSLPDSGTRIEVKAPLNKEDSYDD

Nucleotide

• Length: 1044 bp

>NTDB_id=672561 MUA13_RS09610 WP_001017131.1 1964262..1965305(-) (vraS) [Staphylococcus aureus strain IVB6168]
ATGAACCACTACATTAGAACAATTGGTTCAATGCTCATCTTAGTATATAGCATGCTAGCTGCATTTCTATTCATCGATAA
AGTTTTTGTAAATATCATCTATTTTCAAGGTATGTTTTATACACAAATATTCGGAATACCAGTCTTTTTATTTTTAAATC
TCATCATCATATTATTGTGTATTATTGTTGGTTCGGTACTCGCATACAAAATCAATCAGCAAAATGATTGGATTAAGACG
CAAATTGAGCGTTCAATGGAAGGCGAAACAGTTGGCATTAATGATCAAAATATAGAAATATATAGTGAAACGTTAGATTT
ATACCATACACTCGTACCTTTAAATCAAGAGTTGCATAAGTTGCGACTTAAAACTCAAAATTTAACCAATGAAAATTATA
ATATTAATGATGTGAAAGTTAAAAAGATTATTGAAGATGAACGTCAAAGACTGGCTCGAGAACTTCACGATTCTGTTAGT
CAGCAACTTTTTGCGGCAAGTATGATGTTATCTGCTATCAAAGAAACGAAGTTAGAACCACCATTAGACCAACAAATTCC
GATTTTAGAGAAAATGGTTCAAGATTCGCAGTTAGAAATGCGTGCTTTGCTGTTACATTTAAGACCGCTTGGTTTAAAAG
ACAAATCTTTAGGTGAGGGTATTAAAGATTTAGTTATTGATTTACAAAAAAAAGTGCCGATGAAAGTTGTGCATGAAATA
CAAGATTTTAAAGTGCCTAAAGGTATTGAAGATCATTTGTTCAGAATTACACAGGAAGCAATTTCGAATACATTGCGTCA
TTCAAACGGTACAAAAGTGACAGTAGAATTGTTTAATAAAGACGATTATTTATTGTTGAGAATTCAAGACAATGGTAAAG
GTTTTAATGTTGATGAAAAATTAGAACAAAGTTATGGACTTAAAAATATGCGTGAAAGAGCTTTGGAAATTGGTGCAACG
TTCCATATTGTATCATTGCCAGATTCAGGTACACGTATCGAGGTGAAAGCACCTTTAAATAAGGAGGATTCGTATGACGA
TTAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (249-340)

• Histidine kinase (HisKA_3) (147-210)

3D structure

• AlphaFold DB: A0A0D1IMN4

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vraS	Staphylococcus aureus N315	100	100	1