Detailed information NTG0672480

Bioinformatically predicted

Overview

• Name: braS
• Type: Regulator
• Locus tag: MUA59_RS13415
• Genome accession: NZ_CP094782
• Coordinates: 2673291..2674178 (-)
• Length: 295 a.a.
• NCBI ID: WP_000143420.1
• Uniprot ID: A0A2S6DP21
• Organism: Staphylococcus aureus strain IVB6172
• Function: promote expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 2668291..2679178

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
MUA59_RS13390 (MUA59_13355)	-	2668305..2668397 (+)	93	WP_010956583.1	hypothetical protein	-
MUA59_RS13395 (MUA59_13360)	-	2668505..2669002 (-)	498	WP_262538011.1	glutathione peroxidase	-
MUA59_RS13400 (MUA59_13365)	-	2669012..2669272 (-)	261	WP_014532715.1	hypothetical protein	-
MUA59_RS13405 (MUA59_13370)	-	2670430..2672430 (-)	2001	WP_262607737.1	ABC transporter permease	-
MUA59_RS13410 (MUA59_13375)	-	2672427..2673183 (-)	757	Protein_2604	ABC transporter ATP-binding protein	-
MUA59_RS13415 (MUA59_13380)	braS	2673291..2674178 (-)	888	WP_000143420.1	nisin susceptibility-associated two-component system sensor histidine kinase NsaS	Regulator
MUA59_RS13420 (MUA59_13385)	braR	2674189..2674854 (-)	666	WP_000697877.1	nisin susceptibility-associated two-component system response regulator NsaR	Regulator
MUA59_RS13425 (MUA59_13390)	-	2674880..2675080 (-)	201	WP_262607738.1	hypothetical protein	-
MUA59_RS13430 (MUA59_13395)	-	2675278..2676702 (+)	1425	WP_000948998.1	alkaline phosphatase	-
MUA59_RS13915	-	2676762..2676863 (-)	102	WP_000731972.1	SE2200 family small protein	-
MUA59_RS13440 (MUA59_13405)	-	2676985..2677440 (-)	456	WP_000106185.1	MarR family winged helix-turn-helix transcriptional regulator	-
MUA59_RS13445 (MUA59_13410)	-	2677685..2678446 (-)	762	WP_000323448.1	alpha/beta hydrolase family protein	-

Sequence

Protein

• Length: 295 a.a.
• Molecular weight: 34045.32 Da
• Isoelectric Point: 5.8962

>NTDB_id=672480 MUA59_RS13415 WP_000143420.1 2673291..2674178(-) (braS) [Staphylococcus aureus strain IVB6172]
MTFLKSITQEIAIVIVIFALFGLMFYLYHLPLEAYLLALGVILLLLLIFIGIKYLSFVKTISQQQQIENLENALYQLKNE
QIEYKNDVESYFLTWVHQMKTPITAAQLLLERDEPNVVNRVRQEVIQIDNYTSLALSYLKLLNETSDISVTKISINNIIR
PIIMKYSIQFIDQKTKIHYEPCHHEVLTDVRWTSLMIEQLINNALKYARGKDIWIEFDEQSNQLYVKDNGIGISEADLPK
IFDKGYSGYNGQRQSNSSGIGLFIVKQISTHTNHPVSVVSKQNEGTTFTIQFPDE

Nucleotide

• Length: 888 bp

>NTDB_id=672480 MUA59_RS13415 WP_000143420.1 2673291..2674178(-) (braS) [Staphylococcus aureus strain IVB6172]
ATGACCTTTCTTAAAAGTATTACTCAGGAAATAGCAATAGTCATAGTTATTTTTGCTTTATTTGGCTTAATGTTTTACCT
GTATCATTTGCCATTAGAAGCATATTTACTAGCACTTGGCGTTATTTTATTATTATTACTCATATTTATAGGTATTAAAT
ATTTAAGTTTTGTAAAAACTATAAGCCAACAACAACAAATTGAAAACTTAGAAAATGCGTTGTATCAGCTTAAAAATGAA
CAAATTGAATATAAAAATGATGTAGAGAGCTACTTTTTAACATGGGTACATCAAATGAAAACACCCATTACTGCAGCACA
ACTGTTACTTGAAAGAGATGAGCCTAATGTTGTGAATCGTGTTCGTCAAGAGGTTATTCAAATTGATAACTATACAAGTT
TAGCACTTAGTTATTTAAAGTTATTAAATGAAACTTCTGATATTTCTGTCACTAAAATTTCGATTAACAATATCATTCGC
CCAATTATTATGAAATATTCAATACAGTTTATTGATCAAAAAACAAAAATCCATTATGAACCTTGTCATCACGAAGTATT
AACTGACGTTAGATGGACCTCTTTAATGATAGAACAATTAATAAATAATGCACTTAAGTATGCGAGAGGTAAAGATATAT
GGATTGAATTTGATGAGCAATCCAATCAATTATACGTAAAAGATAATGGTATCGGTATTAGTGAAGCGGACTTGCCTAAA
ATATTTGATAAGGGCTATTCAGGTTATAATGGCCAGCGGCAAAGTAACTCAAGTGGGATTGGTTTATTTATCGTAAAACA
AATTTCAACTCACACAAACCATCCTGTTTCAGTCGTATCTAAACAAAATGAGGGTACAACATTTACGATTCAATTTCCAG
ATGAATAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (191-294)

3D structure

• AlphaFold DB: A0A2S6DP21

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
braS	Staphylococcus aureus N315	99.322	100	0.993