Detailed information NTG0672437

Bioinformatically predicted

Overview

• Name: braS
• Type: Regulator
• Locus tag: MUA18_RS13270
• Genome accession: NZ_CP094780
• Coordinates: 2682190..2683077 (-)
• Length: 295 a.a.
• NCBI ID: WP_000143420.1
• Uniprot ID: A0A2S6DP21
• Organism: Staphylococcus aureus strain IVB6173
• Function: promote expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 2677190..2688077

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
MUA18_RS13240 (MUA18_13235)	-	2677193..2677285 (+)	93	WP_010956583.1	hypothetical protein	-
MUA18_RS13245 (MUA18_13240)	-	2677393..2677890 (-)	498	WP_001065267.1	glutathione peroxidase	-
MUA18_RS13250 (MUA18_13245)	-	2677900..2678160 (-)	261	WP_014532715.1	hypothetical protein	-
MUA18_RS13255 (MUA18_13250)	-	2678542..2678655 (-)	114	WP_072357681.1	hypothetical protein	-
MUA18_RS13260 (MUA18_13255)	-	2679330..2681330 (-)	2001	WP_000776732.1	ABC transporter permease	-
MUA18_RS13265 (MUA18_13260)	-	2681327..2682082 (-)	756	WP_044122909.1	ABC transporter ATP-binding protein	-
MUA18_RS13270 (MUA18_13265)	braS	2682190..2683077 (-)	888	WP_000143420.1	nisin susceptibility-associated two-component system sensor histidine kinase NsaS	Regulator
MUA18_RS13275 (MUA18_13270)	braR	2683088..2683753 (-)	666	WP_000697877.1	nisin susceptibility-associated two-component system response regulator NsaR	Regulator
MUA18_RS13280 (MUA18_13275)	-	2683779..2683979 (-)	201	WP_000604727.1	hypothetical protein	-
MUA18_RS13285 (MUA18_13280)	-	2684177..2685601 (+)	1425	WP_262541982.1	alkaline phosphatase	-
MUA18_RS13935	-	2685661..2685762 (-)	102	WP_000731972.1	SE2200 family small protein	-
MUA18_RS13295 (MUA18_13290)	-	2685884..2686339 (-)	456	WP_000106185.1	MarR family winged helix-turn-helix transcriptional regulator	-
MUA18_RS13300 (MUA18_13295)	-	2686584..2687345 (-)	762	WP_000323443.1	alpha/beta hydrolase family protein	-

Sequence

Protein

• Length: 295 a.a.
• Molecular weight: 34045.32 Da
• Isoelectric Point: 5.8962

>NTDB_id=672437 MUA18_RS13270 WP_000143420.1 2682190..2683077(-) (braS) [Staphylococcus aureus strain IVB6173]
MTFLKSITQEIAIVIVIFALFGLMFYLYHLPLEAYLLALGVILLLLLIFIGIKYLSFVKTISQQQQIENLENALYQLKNE
QIEYKNDVESYFLTWVHQMKTPITAAQLLLERDEPNVVNRVRQEVIQIDNYTSLALSYLKLLNETSDISVTKISINNIIR
PIIMKYSIQFIDQKTKIHYEPCHHEVLTDVRWTSLMIEQLINNALKYARGKDIWIEFDEQSNQLYVKDNGIGISEADLPK
IFDKGYSGYNGQRQSNSSGIGLFIVKQISTHTNHPVSVVSKQNEGTTFTIQFPDE

Nucleotide

• Length: 888 bp

>NTDB_id=672437 MUA18_RS13270 WP_000143420.1 2682190..2683077(-) (braS) [Staphylococcus aureus strain IVB6173]
ATGACCTTTCTTAAAAGTATTACTCAGGAAATAGCAATAGTCATAGTTATTTTTGCTTTATTTGGCTTAATGTTTTACCT
GTATCATTTGCCATTAGAAGCATATTTACTAGCACTTGGCGTTATTTTATTATTATTACTCATATTTATAGGTATTAAAT
ATTTAAGTTTTGTAAAAACTATAAGCCAACAACAACAAATTGAAAACTTAGAAAATGCGTTGTATCAGCTTAAAAATGAA
CAAATTGAATATAAAAATGATGTAGAGAGCTACTTTTTAACATGGGTACATCAAATGAAAACACCCATTACTGCAGCACA
ACTGTTACTTGAAAGAGATGAGCCTAATGTTGTGAATCGTGTTCGTCAAGAGGTTATTCAAATTGATAACTATACAAGTT
TAGCACTTAGTTATTTAAAGTTATTAAATGAAACTTCTGATATTTCTGTCACTAAAATTTCGATTAACAATATCATTCGC
CCAATTATTATGAAATATTCAATACAGTTTATTGATCAAAAAACAAAAATCCATTATGAACCTTGTCATCACGAAGTATT
AACTGACGTTAGATGGACCTCTTTAATGATAGAACAATTAATAAATAATGCACTTAAGTATGCGAGAGGTAAAGATATAT
GGATTGAATTTGATGAGCAATCCAATCAATTATACGTAAAAGATAATGGTATCGGTATTAGTGAAGCGGACTTGCCTAAA
ATATTTGATAAGGGCTATTCAGGTTATAATGGCCAGCGGCAAAGTAACTCAAGTGGGATTGGTTTATTTATCGTAAAACA
AATTTCAACTCACACAAACCATCCTGTTTCAGTCGTATCTAAACAAAATGAGGGTACAACATTTACGATTCAATTTCCAG
ATGAATAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (191-294)

3D structure

• AlphaFold DB: A0A2S6DP21

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
braS	Staphylococcus aureus N315	99.322	100	0.993