Detailed information    

insolico Bioinformatically predicted

Overview

Name   agrA   Type   Regulator
Locus tag   MUA18_RS10200 Genome accession   NZ_CP094780
Coordinates   2077457..2078173 (+) Length   238 a.a.
NCBI ID   WP_000688492.1    Uniprot ID   A0A7U7IEW1
Organism   Staphylococcus aureus strain IVB6173     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 2072457..2083173
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  MUA18_RS10170 (MUA18_10165) - 2072673..2073299 (+) 627 WP_000522384.1 nitroreductase family protein -
  MUA18_RS10175 (MUA18_10170) - 2073661..2074446 (+) 786 WP_000867945.1 carbon-nitrogen family hydrolase -
  MUA18_RS10180 (MUA18_10175) hld 2075045..2075125 (-) 81 WP_000046022.1 delta-hemolysin -
  MUA18_RS10185 (MUA18_10180) - 2075416..2075979 (+) 564 WP_001105699.1 accessory gene regulator AgrB -
  MUA18_RS10190 (MUA18_10185) agrD 2075982..2076125 (+) 144 WP_001094921.1 cyclic lactone autoinducer peptide AgrD -
  MUA18_RS10195 (MUA18_10190) agrC 2076155..2077438 (+) 1284 WP_000447894.1 quorum-sensing sensor histidine kinase AgrC -
  MUA18_RS10200 (MUA18_10195) agrA 2077457..2078173 (+) 717 WP_000688492.1 quorum-sensing response regulator AgrA Regulator
  MUA18_RS10205 (MUA18_10200) - 2078245..2078352 (+) 108 WP_001803734.1 hypothetical protein -
  MUA18_RS10210 (MUA18_10205) - 2078540..2079499 (-) 960 WP_262529043.1 carbohydrate kinase -
  MUA18_RS10215 (MUA18_10210) - 2079496..2080980 (-) 1485 WP_262543003.1 sucrose-6-phosphate hydrolase -
  MUA18_RS10220 (MUA18_10215) - 2081129..2082079 (-) 951 WP_000790321.1 LacI family DNA-binding transcriptional regulator -

Sequence

Protein


Download         Length: 238 a.a.        Molecular weight: 27905.90 Da        Isoelectric Point: 6.0927

>NTDB_id=672433 MUA18_RS10200 WP_000688492.1 2077457..2078173(+) (agrA) [Staphylococcus aureus strain IVB6173]
MKIFICEDDPKQRENMVTIIKNYIMIEEKPMEIALATDNPYEVLEQAKNMNDIGCYFLDIQLSTDINGIKLGSEIRKHDP
VGNIIFVTSHSELTYLTFVYKVAAMDFIFKDDPAELRTRIIDCLETAHTRLQLLSKDNSVETIELKRGSNSVYVQYDDIM
FFESSTKSHRLIAHLDNRQIEFYGNLKELSQLDDRFFRCHNSFVVNRHNIESIDSKERIVYFKNKEHCYASVRNVKKI

Nucleotide


Download         Length: 717 bp        

>NTDB_id=672433 MUA18_RS10200 WP_000688492.1 2077457..2078173(+) (agrA) [Staphylococcus aureus strain IVB6173]
ATGAAAATTTTCATTTGCGAAGACGATCCAAAACAAAGAGAAAACATGGTTACCATTATTAAAAATTATATAATGATAGA
AGAAAAGCCTATGGAAATTGCCCTCGCAACTGATAATCCTTATGAGGTGCTTGAGCAAGCTAAAAATATGAATGACATAG
GCTGTTACTTTTTAGATATTCAACTTTCAACTGATATTAATGGTATCAAATTAGGCAGTGAAATTCGTAAGCATGATCCA
GTTGGTAACATTATATTTGTTACGAGTCACAGTGAACTTACCTATTTAACGTTTGTCTACAAAGTTGCAGCGATGGATTT
TATTTTTAAAGATGATCCAGCTGAATTAAGAACTCGAATTATAGACTGTTTAGAAACTGCACATACACGCTTACAATTGT
TGTCTAAAGATAATAGCGTTGAAACGATTGAATTAAAACGTGGCAGTAATTCAGTGTATGTTCAATATGATGATATTATG
TTTTTTGAATCATCAACAAAATCTCACAGACTCATTGCCCATTTAGATAACCGTCAAATTGAATTTTATGGTAATTTAAA
AGAACTGAGTCAATTAGATGATCGTTTCTTTAGATGTCATAATAGCTTTGTCGTCAATCGCCATAACATTGAATCTATAG
ATTCGAAAGAGCGAATTGTCTATTTTAAAAATAAAGAACACTGCTATGCATCGGTGAGAAACGTTAAAAAAATATAA

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(3-120)

LytTr DNA-binding domain (LytTR)

(151-237)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A7U7IEW1

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  agrA Staphylococcus aureus N315

100

100

1