Detailed information NTG0672392

Bioinformatically predicted

Overview

• Name: vraS
• Type: Regulator
• Locus tag: MUA10_RS10235
• Genome accession: NZ_CP094778
• Coordinates: 2058175..2059218 (-)
• Length: 347 a.a.
• NCBI ID: WP_001017131.1
• Uniprot ID: A0A0D1IMN4
• Organism: Staphylococcus aureus strain IVB6185
• Function: repress expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 2053175..2064218

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
MUA10_RS10205 (MUA10_10200)	-	2053596..2054852 (-)	1257	WP_001793983.1	aminopeptidase	-
MUA10_RS10210 (MUA10_10205)	-	2054855..2055055 (-)	201	WP_000180460.1	DUF1128 family protein	-
MUA10_RS10215 (MUA10_10210)	-	2055202..2055666 (+)	465	WP_000228670.1	low molecular weight protein-tyrosine-phosphatase	-
MUA10_RS10220 (MUA10_10215)	-	2055673..2055948 (+)	276	WP_000428172.1	YtxH domain-containing protein	-
MUA10_RS10225 (MUA10_10220)	-	2056226..2057443 (+)	1218	WP_000037081.1	YihY/virulence factor BrkB family protein	-
MUA10_RS10230 (MUA10_10225)	vraR	2057556..2058185 (-)	630	WP_000153535.1	two-component system response regulator VraR	Regulator
MUA10_RS10235 (MUA10_10230)	vraS	2058175..2059218 (-)	1044	WP_001017131.1	sensor histidine kinase	Regulator
MUA10_RS10240 (MUA10_10235)	liaF	2059215..2059916 (-)	702	WP_000149064.1	cell wall-active antibiotics response protein LiaF	-
MUA10_RS10245 (MUA10_10240)	-	2059931..2060317 (-)	387	WP_001110178.1	hypothetical protein	-
MUA10_RS10250 (MUA10_10245)	map	2060534..2061292 (-)	759	WP_000636142.1	type I methionyl aminopeptidase	-
MUA10_RS10255 (MUA10_10250)	-	2062048..2063034 (+)	987	WP_001014423.1	aromatic acid exporter family protein	-
MUA10_RS10260 (MUA10_10255)	-	2063223..2063636 (-)	414	WP_001643743.1	hypothetical protein	-
MUA10_RS10265 (MUA10_10260)	-	2063665..2063775 (-)	111	WP_001790257.1	hypothetical protein	-

Sequence

Protein

• Length: 347 a.a.
• Molecular weight: 40044.52 Da
• Isoelectric Point: 6.0577

>NTDB_id=672392 MUA10_RS10235 WP_001017131.1 2058175..2059218(-) (vraS) [Staphylococcus aureus strain IVB6185]
MNHYIRTIGSMLILVYSMLAAFLFIDKVFVNIIYFQGMFYTQIFGIPVFLFLNLIIILLCIIVGSVLAYKINQQNDWIKT
QIERSMEGETVGINDQNIEIYSETLDLYHTLVPLNQELHKLRLKTQNLTNENYNINDVKVKKIIEDERQRLARELHDSVS
QQLFAASMMLSAIKETKLEPPLDQQIPILEKMVQDSQLEMRALLLHLRPLGLKDKSLGEGIKDLVIDLQKKVPMKVVHEI
QDFKVPKGIEDHLFRITQEAISNTLRHSNGTKVTVELFNKDDYLLLRIQDNGKGFNVDEKLEQSYGLKNMRERALEIGAT
FHIVSLPDSGTRIEVKAPLNKEDSYDD

Nucleotide

• Length: 1044 bp

>NTDB_id=672392 MUA10_RS10235 WP_001017131.1 2058175..2059218(-) (vraS) [Staphylococcus aureus strain IVB6185]
ATGAACCACTACATTAGAACAATTGGTTCAATGCTCATCTTAGTATATAGCATGCTAGCTGCATTTCTGTTCATCGATAA
AGTTTTTGTAAATATCATCTATTTTCAAGGTATGTTTTATACACAAATATTCGGAATACCAGTCTTTTTATTTTTAAATC
TCATCATCATATTATTGTGTATTATTGTTGGTTCGGTACTCGCTTACAAAATCAATCAGCAAAATGATTGGATTAAGACG
CAAATTGAGCGTTCAATGGAAGGCGAAACAGTTGGCATTAATGATCAAAATATAGAAATATATAGTGAAACGTTAGACTT
ATACCATACACTTGTACCTTTAAATCAAGAATTGCATAAGTTGCGACTTAAAACTCAAAACTTAACCAATGAAAATTATA
ATATTAATGATGTGAAAGTTAAAAAGATTATTGAAGATGAACGTCAAAGACTAGCACGAGAACTTCACGATTCTGTTAGT
CAGCAACTTTTTGCGGCAAGTATGATGCTTTCTGCTATCAAAGAAACGAAGTTAGAACCACCATTAGACCAACAAATTCC
GATTTTAGAGAAAATGGTTCAAGATTCGCAGCTAGAAATGCGTGCTTTGCTGTTACATTTAAGACCGCTTGGTTTAAAAG
ACAAATCTTTAGGTGAGGGTATTAAAGATTTAGTTATTGATTTACAAAAAAAAGTGCCAATGAAAGTTGTGCATGAAATA
CAAGATTTTAAAGTGCCTAAAGGTATTGAAGATCATTTGTTCAGAATTACACAGGAAGCAATTTCGAATACATTGCGTCA
TTCAAACGGTACAAAAGTGACAGTAGAATTGTTTAATAAAGACGATTATTTATTGTTGAGAATTCAAGACAATGGTAAAG
GTTTTAATGTTGATGAAAAATTAGAACAAAGTTATGGACTTAAAAATATGCGTGAAAGAGCTTTGGAAATTGGTGCAACG
TTCCATATTGTATCATTGCCAGATTCAGGTACACGTATCGAGGTGAAAGCACCTTTAAATAAGGAGGATTCGTATGACGA
TTAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (249-340)

• Histidine kinase (HisKA_3) (147-210)

3D structure

• AlphaFold DB: A0A0D1IMN4

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vraS	Staphylococcus aureus N315	100	100	1