Detailed information NTG0672356

Bioinformatically predicted

Overview

• Name: braS
• Type: Regulator
• Locus tag: MUA69_RS13400
• Genome accession: NZ_CP094775
• Coordinates: 2679956..2680843 (-)
• Length: 295 a.a.
• NCBI ID: WP_000143420.1
• Uniprot ID: A0A2S6DP21
• Organism: Staphylococcus aureus strain IVB6191
• Function: promote expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 2674956..2685843

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
MUA69_RS13375 (MUA69_13350)	-	2674970..2675062 (+)	93	WP_010956583.1	hypothetical protein	-
MUA69_RS13380 (MUA69_13355)	-	2675170..2675667 (-)	498	WP_262538011.1	glutathione peroxidase	-
MUA69_RS13385 (MUA69_13360)	-	2675677..2675937 (-)	261	WP_014532715.1	hypothetical protein	-
MUA69_RS13390 (MUA69_13365)	-	2677095..2679095 (-)	2001	WP_262607737.1	ABC transporter permease	-
MUA69_RS13395 (MUA69_13370)	-	2679092..2679848 (-)	757	Protein_2598	ABC transporter ATP-binding protein	-
MUA69_RS13400 (MUA69_13375)	braS	2679956..2680843 (-)	888	WP_000143420.1	nisin susceptibility-associated two-component system sensor histidine kinase NsaS	Regulator
MUA69_RS13405 (MUA69_13380)	braR	2680854..2681519 (-)	666	WP_000697877.1	nisin susceptibility-associated two-component system response regulator NsaR	Regulator
MUA69_RS13410 (MUA69_13385)	-	2681545..2681745 (-)	201	WP_262607738.1	hypothetical protein	-
MUA69_RS13415 (MUA69_13390)	-	2681943..2683367 (+)	1425	WP_000948998.1	alkaline phosphatase	-
MUA69_RS13950	-	2683427..2683528 (-)	102	WP_000731972.1	SE2200 family small protein	-
MUA69_RS13425 (MUA69_13400)	-	2683650..2684105 (-)	456	WP_000106185.1	MarR family winged helix-turn-helix transcriptional regulator	-
MUA69_RS13430 (MUA69_13405)	-	2684350..2685111 (-)	762	WP_000323448.1	alpha/beta hydrolase	-

Sequence

Protein

• Length: 295 a.a.
• Molecular weight: 34045.32 Da
• Isoelectric Point: 5.8962

>NTDB_id=672356 MUA69_RS13400 WP_000143420.1 2679956..2680843(-) (braS) [Staphylococcus aureus strain IVB6191]
MTFLKSITQEIAIVIVIFALFGLMFYLYHLPLEAYLLALGVILLLLLIFIGIKYLSFVKTISQQQQIENLENALYQLKNE
QIEYKNDVESYFLTWVHQMKTPITAAQLLLERDEPNVVNRVRQEVIQIDNYTSLALSYLKLLNETSDISVTKISINNIIR
PIIMKYSIQFIDQKTKIHYEPCHHEVLTDVRWTSLMIEQLINNALKYARGKDIWIEFDEQSNQLYVKDNGIGISEADLPK
IFDKGYSGYNGQRQSNSSGIGLFIVKQISTHTNHPVSVVSKQNEGTTFTIQFPDE

Nucleotide

• Length: 888 bp

>NTDB_id=672356 MUA69_RS13400 WP_000143420.1 2679956..2680843(-) (braS) [Staphylococcus aureus strain IVB6191]
ATGACCTTTCTTAAAAGTATTACTCAGGAAATAGCAATAGTCATAGTTATTTTTGCTTTATTTGGCTTAATGTTTTACCT
GTATCATTTGCCATTAGAAGCATATTTACTAGCACTTGGCGTTATTTTATTATTATTACTCATATTTATAGGTATTAAAT
ATTTAAGTTTTGTAAAAACTATAAGCCAACAACAACAAATTGAAAACTTAGAAAATGCGTTGTATCAGCTTAAAAATGAA
CAAATTGAATATAAAAATGATGTAGAGAGCTACTTTTTAACATGGGTACATCAAATGAAAACACCCATTACTGCAGCACA
ACTGTTACTTGAAAGAGATGAGCCTAATGTTGTGAATCGTGTTCGTCAAGAGGTTATTCAAATTGATAACTATACAAGTT
TAGCACTTAGTTATTTAAAGTTATTAAATGAAACTTCTGATATTTCTGTCACTAAAATTTCGATTAACAATATCATTCGC
CCAATTATTATGAAATATTCAATACAGTTTATTGATCAAAAAACAAAAATCCATTATGAACCTTGTCATCACGAAGTATT
AACTGACGTTAGATGGACCTCTTTAATGATAGAACAATTAATAAATAATGCACTTAAGTATGCGAGAGGTAAAGATATAT
GGATTGAATTTGATGAGCAATCCAATCAATTATACGTAAAAGATAATGGTATCGGTATTAGTGAAGCGGACTTGCCTAAA
ATATTTGATAAGGGCTATTCAGGTTATAATGGCCAGCGGCAAAGTAACTCAAGTGGGATTGGTTTATTTATCGTAAAACA
AATTTCAACTCACACAAACCATCCTGTTTCAGTCGTATCTAAACAAAATGAGGGTACAACATTTACGATTCAATTTCCAG
ATGAATAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (191-294)

3D structure

• AlphaFold DB: A0A2S6DP21

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
braS	Staphylococcus aureus N315	99.322	100	0.993