Detailed information    

insolico Bioinformatically predicted

Overview

Name   agrA   Type   Regulator
Locus tag   MUA69_RS10370 Genome accession   NZ_CP094775
Coordinates   2072408..2073124 (+) Length   238 a.a.
NCBI ID   WP_000688492.1    Uniprot ID   A0A7U7IEW1
Organism   Staphylococcus aureus strain IVB6191     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 2067408..2078124
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  MUA69_RS10340 (MUA69_10315) - 2067625..2068251 (+) 627 WP_262607628.1 nitroreductase family protein -
  MUA69_RS10345 (MUA69_10320) - 2068612..2069397 (+) 786 WP_262538420.1 carbon-nitrogen family hydrolase -
  MUA69_RS10350 (MUA69_10325) hld 2069996..2070076 (-) 81 WP_000046022.1 delta-hemolysin -
  MUA69_RS10355 (MUA69_10330) - 2070367..2070930 (+) 564 WP_001105699.1 accessory gene regulator AgrB -
  MUA69_RS10360 (MUA69_10335) agrD 2070933..2071076 (+) 144 WP_001094921.1 cyclic lactone autoinducer peptide AgrD -
  MUA69_RS10365 (MUA69_10340) agrC 2071106..2072389 (+) 1284 WP_262607630.1 quorum-sensing sensor histidine kinase AgrC -
  MUA69_RS10370 (MUA69_10345) agrA 2072408..2073124 (+) 717 WP_000688492.1 quorum-sensing response regulator AgrA Regulator
  MUA69_RS10375 (MUA69_10350) - 2073196..2073303 (+) 108 WP_042900011.1 hypothetical protein -
  MUA69_RS10380 (MUA69_10355) - 2073493..2074452 (-) 960 WP_262607631.1 carbohydrate kinase family protein -
  MUA69_RS10385 (MUA69_10360) - 2074449..2075933 (-) 1485 WP_262538414.1 sucrose-6-phosphate hydrolase -
  MUA69_RS10390 (MUA69_10365) - 2076083..2077033 (-) 951 WP_000790321.1 LacI family DNA-binding transcriptional regulator -

Sequence

Protein


Download         Length: 238 a.a.        Molecular weight: 27905.90 Da        Isoelectric Point: 6.0927

>NTDB_id=672352 MUA69_RS10370 WP_000688492.1 2072408..2073124(+) (agrA) [Staphylococcus aureus strain IVB6191]
MKIFICEDDPKQRENMVTIIKNYIMIEEKPMEIALATDNPYEVLEQAKNMNDIGCYFLDIQLSTDINGIKLGSEIRKHDP
VGNIIFVTSHSELTYLTFVYKVAAMDFIFKDDPAELRTRIIDCLETAHTRLQLLSKDNSVETIELKRGSNSVYVQYDDIM
FFESSTKSHRLIAHLDNRQIEFYGNLKELSQLDDRFFRCHNSFVVNRHNIESIDSKERIVYFKNKEHCYASVRNVKKI

Nucleotide


Download         Length: 717 bp        

>NTDB_id=672352 MUA69_RS10370 WP_000688492.1 2072408..2073124(+) (agrA) [Staphylococcus aureus strain IVB6191]
ATGAAAATTTTCATTTGCGAAGACGATCCAAAACAAAGAGAAAACATGGTTACCATTATTAAAAATTATATAATGATAGA
AGAAAAGCCTATGGAAATTGCCCTCGCAACTGATAATCCTTATGAGGTGCTTGAGCAAGCTAAAAATATGAATGACATAG
GCTGTTACTTTTTAGATATTCAACTTTCAACTGATATTAATGGTATCAAATTAGGCAGTGAAATTCGTAAGCATGATCCA
GTTGGTAACATTATATTTGTTACGAGTCACAGTGAACTTACCTATTTAACGTTTGTCTACAAAGTTGCAGCGATGGATTT
TATTTTTAAAGATGATCCAGCTGAATTAAGAACTCGAATTATAGACTGTTTAGAAACTGCACATACACGCTTACAATTGT
TGTCTAAAGATAATAGCGTTGAAACGATTGAATTAAAACGTGGCAGTAATTCAGTGTATGTTCAATATGATGATATTATG
TTTTTTGAATCATCAACAAAATCTCACAGACTCATTGCCCATTTAGATAACCGTCAAATTGAATTTTATGGTAATTTAAA
AGAACTGAGTCAATTAGATGATCGTTTCTTTAGATGTCATAATAGCTTTGTCGTCAATCGCCATAATATTGAATCTATAG
ATTCGAAAGAGCGAATTGTCTATTTTAAAAATAAAGAACACTGCTATGCATCGGTGAGAAACGTTAAAAAAATATAA

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(3-120)

LytTr DNA-binding domain (LytTR)

(151-237)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A7U7IEW1

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  agrA Staphylococcus aureus N315

100

100

1