Detailed information NTG0067235

Bioinformatically predicted

Overview

• Name: clpC
• Type: Regulator
• Locus tag: SITYG_RS01120
• Genome accession: NZ_AP014880
• Coordinates: 214477..216906 (+)
• Length: 809 a.a.
• NCBI ID: WP_096362458.1
• Uniprot ID: A0AAD1C5L3
• Organism: Streptococcus intermedius strain TYG1620
• Function: degradation of ComW (predicted from homology) Competence regulation

Genomic Context

Location: 209477..221906

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
SITYG_RS01090 (SITYG_02010)	-	209992..210777 (+)	786	WP_096362456.1	hypothetical protein	-
SITYG_RS01100 (SITYG_02020)	rpsB	211419..212201 (+)	783	WP_003074779.1	30S ribosomal protein S2	-
SITYG_RS01105 (SITYG_02030)	tsf	212284..213327 (+)	1044	WP_096362457.1	translation elongation factor Ts	-
SITYG_RS01110 (SITYG_02040)	-	213403..213753 (-)	351	WP_003074775.1	hypothetical protein	-
SITYG_RS01115 (SITYG_02050)	-	214012..214473 (+)	462	WP_003077510.1	CtsR family transcriptional regulator	-
SITYG_RS01120 (SITYG_02060)	clpC	214477..216906 (+)	2430	WP_096362458.1	ATP-dependent Clp protease ATP-binding subunit	Regulator
SITYG_RS01125 (SITYG_02070)	-	216953..217393 (+)	441	WP_096362459.1	GNAT family N-acetyltransferase	-
SITYG_RS01130 (SITYG_02080)	dusB	217464..218435 (-)	972	WP_162287164.1	tRNA dihydrouridine synthase DusB	-
SITYG_RS01135 (SITYG_02090)	hslO	218422..219294 (-)	873	WP_231870247.1	Hsp33 family molecular chaperone HslO	-
SITYG_RS01140 (SITYG_02100)	-	219503..220774 (-)	1272	WP_096362461.1	toxic anion resistance protein	-
SITYG_RS01145 (SITYG_02110)	-	220793..221611 (-)	819	WP_096362462.1	hypothetical protein	-

Sequence

Protein

• Length: 809 a.a.
• Molecular weight: 90127.33 Da
• Isoelectric Point: 6.1463

>NTDB_id=67235 SITYG_RS01120 WP_096362458.1 214477..216906(+) (clpC) [Streptococcus intermedius strain TYG1620]
MKYSKALTESIESAQLLASHFETDYLESWQLLIAMANNPYSVAGSVLNDYPLEIDDFEKAAFHITGKVYQQEGDFTIWPF
SYRMKVLFLTAEQIAGAVHANNLGTEHVLLAMLFDRGSLAARILEFIGFSYEDKEGVLRMTDLRKNLEHKASWNKEDLKA
IRHLNKSAAATRQTMANMMGMPPATSGGLEDYTRDLTEMAHMGLLEPVIGRDKEISRILQILSRKTKNNPVLVGDAGVGK
TALALGLAQRVADGQVPNELAKMRVLELDLMNVVAGTRFRGDFEERMNNIINDIEADGHVILFIDELHTIMGSGSGIDST
LDAANILKPALAKGTLRTIGATTQEEYQKYIEKDAALSRRFAKVTIEEPTVADSIAILQGLKKSYEDHHKVVITDSAIET
AVKYAHRYLTSKHLPDSAIDLLDEAAARVQNKSPQNHVKAELSAADEALMAGDWNKVDTLLEKESQPIVYKLRVKDEDVL
ATLSSLSGIPVQKLTQTDAKKYLNLEKELHKRVIGQNEAISAISRAIRRNQSGIRTSKRPIGSFLFLGPTGVGKTELAKA
LAEVLFDDETALIRFDMSEYMEKFAASRLNGAPPGYVGYEEGGELTEKVRNRPYSVLLFDEVEKAHPDIFNVLLQVLDDG
VLTDSKGRKVDFSNTIIIMTSNLGATSLRDDKTVGFGARDVRFDHENMEKRMMEELKKAYRPEFINRIDEKVVFHSLTSE
DMQEVVKIMVQPLISSLTEKGIKLKFQLSALKLLAQEGYDPEMGARPLRRILQTRVEDHLSELLLSGELKTGQSLKVGVK
AGKLKFEVL

Nucleotide

• Length: 2430 bp

>NTDB_id=67235 SITYG_RS01120 WP_096362458.1 214477..216906(+) (clpC) [Streptococcus intermedius strain TYG1620]
ATGAAATATTCAAAAGCTTTGACAGAAAGTATTGAATCAGCACAGTTATTAGCAAGTCATTTTGAAACGGATTATTTAGA
GTCTTGGCAGCTGTTGATTGCTATGGCAAATAATCCTTATAGTGTTGCTGGTTCAGTTTTAAATGATTACCCACTTGAGA
TTGATGATTTTGAAAAGGCAGCTTTTCATATCACGGGGAAAGTCTATCAACAAGAGGGAGACTTTACTATTTGGCCGTTT
TCTTATCGCATGAAAGTGCTATTTTTGACTGCTGAACAAATTGCAGGGGCTGTTCATGCTAATAATCTTGGGACAGAGCA
TGTATTGCTAGCTATGTTATTTGACCGAGGAAGCTTGGCAGCGCGTATTCTTGAATTTATTGGTTTTAGTTACGAAGATA
AAGAAGGCGTTTTGCGCATGACAGATCTGCGGAAAAATTTAGAGCATAAGGCCAGCTGGAATAAAGAGGATTTAAAGGCG
ATTCGTCACCTAAATAAAAGTGCTGCAGCAACAAGACAAACGATGGCTAATATGATGGGAATGCCTCCTGCAACCAGTGG
CGGACTAGAAGATTATACTCGTGATCTAACTGAAATGGCTCATATGGGCCTTTTAGAACCGGTCATTGGGCGGGATAAAG
AGATTTCTCGCATACTTCAGATTTTAAGTCGTAAGACAAAAAACAATCCGGTTTTGGTAGGAGATGCAGGAGTTGGGAAG
ACAGCATTAGCTCTGGGTTTGGCGCAACGTGTGGCAGATGGTCAAGTTCCAAATGAGCTTGCAAAGATGAGAGTTTTAGA
GCTAGATTTAATGAATGTGGTGGCTGGAACTCGTTTTCGTGGTGATTTTGAAGAACGGATGAACAATATTATCAATGATA
TTGAAGCAGATGGGCATGTTATTCTCTTCATTGATGAGCTTCATACCATTATGGGGTCTGGCAGCGGGATTGACTCGACA
TTAGATGCAGCAAATATTCTCAAGCCGGCTTTGGCTAAAGGAACGCTCAGAACGATCGGTGCCACAACACAAGAAGAGTA
CCAAAAATATATCGAAAAAGATGCAGCTCTTTCACGAAGATTTGCCAAGGTTACTATTGAAGAACCAACGGTAGCTGACA
GCATTGCTATTTTACAGGGACTCAAGAAAAGTTATGAAGATCACCACAAGGTCGTGATTACGGATTCGGCAATTGAGACG
GCTGTTAAGTATGCGCATCGTTACCTGACTAGTAAACATCTACCTGACTCAGCGATTGACTTGCTAGACGAAGCTGCTGC
AAGGGTACAAAATAAAAGCCCGCAAAATCACGTAAAAGCAGAATTGAGTGCAGCAGATGAGGCTTTAATGGCAGGCGATT
GGAACAAAGTTGATACGTTGTTGGAGAAAGAGAGTCAGCCAATTGTTTATAAATTAAGAGTGAAAGACGAGGATGTTTTA
GCAACACTCAGCAGTTTATCAGGTATTCCTGTGCAAAAGTTGACACAAACAGATGCGAAGAAATACCTCAATTTAGAAAA
GGAGTTACACAAACGAGTTATCGGGCAAAATGAAGCAATTTCTGCTATTAGTCGAGCGATTCGGCGCAATCAATCCGGTA
TCCGCACTAGCAAGCGCCCAATTGGCTCCTTTCTGTTCTTAGGGCCAACTGGGGTCGGAAAAACTGAGCTAGCTAAGGCT
TTGGCAGAAGTTCTCTTTGATGACGAAACAGCGTTAATTCGTTTTGATATGTCCGAATACATGGAGAAATTTGCTGCTAG
TCGTCTCAATGGAGCACCTCCAGGCTATGTTGGTTATGAAGAAGGGGGAGAATTAACTGAAAAGGTGCGTAATCGTCCTT
ACTCTGTGCTCCTCTTTGATGAGGTAGAAAAAGCACATCCTGATATTTTCAATGTGCTGCTCCAAGTCTTAGATGACGGG
GTTCTGACGGATAGCAAGGGCCGTAAGGTAGATTTTTCCAATACTATTATCATTATGACCAGCAATCTTGGTGCGACAAG
TTTACGGGACGATAAGACGGTTGGGTTCGGAGCAAGAGATGTTCGCTTTGATCATGAAAATATGGAAAAACGAATGATGG
AAGAGCTAAAGAAAGCTTATCGTCCAGAATTTATTAACCGAATTGATGAAAAGGTTGTTTTTCACAGTTTGACTAGCGAA
GACATGCAGGAAGTGGTGAAAATTATGGTGCAACCGCTCATTTCTAGTCTTACAGAAAAAGGAATTAAACTCAAATTTCA
ACTGAGTGCTTTGAAGCTTCTAGCTCAAGAGGGCTATGATCCTGAAATGGGAGCTCGTCCATTGCGTCGAATTCTACAAA
CTCGAGTGGAAGACCATTTATCAGAATTACTTTTATCAGGTGAGTTAAAAACGGGGCAAAGCTTGAAAGTCGGTGTCAAG
GCTGGAAAATTGAAGTTTGAAGTGCTCTGA

Domains

Predicted by InterproScan.

• AAA domain (Cdc48 subfamily) (AAA_2) (539-710)

• ATPase family associated with various cellular activities (AAA) (AAA) (231-349)

• Clp amino terminal domain, pathogenicity island component (Clp_N) (91-133)

• Clp amino terminal domain, pathogenicity island component (Clp_N) (14-60)

• C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small) (717-797)

• AAA lid domain (AAA_lid_9) (371-446)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpC	Streptococcus pneumoniae TIGR4	77.189	100	0.774
clpC	Streptococcus pneumoniae Rx1	76.942	100	0.771
clpC	Streptococcus pneumoniae D39	76.942	100	0.771
clpC	Streptococcus mutans UA159	66.38	100	0.669
clpC	Streptococcus thermophilus LMG 18311	64.988	100	0.654
clpC	Streptococcus thermophilus LMD-9	64.865	100	0.653
clpC	Lactococcus lactis subsp. lactis strain DGCC12653	49.279	100	0.507
clpC	Bacillus subtilis subsp. subtilis str. 168	45.761	99.135	0.454