Detailed information NTG0672313

Bioinformatically predicted

Overview

• Name: braS
• Type: Regulator
• Locus tag: MUA47_RS13430
• Genome accession: NZ_CP094773
• Coordinates: 2708586..2709473 (-)
• Length: 295 a.a.
• NCBI ID: WP_000143420.1
• Uniprot ID: A0A2S6DP21
• Organism: Staphylococcus aureus strain IVB6195
• Function: promote expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 2703586..2714473

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
MUA47_RS13400 (MUA47_13400)	-	2703588..2703680 (+)	93	WP_010956583.1	hypothetical protein	-
MUA47_RS13405 (MUA47_13405)	-	2703788..2704285 (-)	498	WP_262634687.1	glutathione peroxidase	-
MUA47_RS13410 (MUA47_13410)	-	2704295..2704555 (-)	261	WP_078064828.1	hypothetical protein	-
MUA47_RS13415 (MUA47_13415)	-	2704937..2705050 (-)	114	WP_072491147.1	hypothetical protein	-
MUA47_RS13420 (MUA47_13420)	-	2705726..2707726 (-)	2001	WP_250426069.1	ABC transporter permease	-
MUA47_RS13425 (MUA47_13425)	-	2707723..2708478 (-)	756	WP_000923770.1	ABC transporter ATP-binding protein	-
MUA47_RS13430 (MUA47_13430)	braS	2708586..2709473 (-)	888	WP_000143420.1	nisin susceptibility-associated two-component system sensor histidine kinase NsaS	Regulator
MUA47_RS13435 (MUA47_13435)	braR	2709484..2710149 (-)	666	WP_000697877.1	nisin susceptibility-associated two-component system response regulator NsaR	Regulator
MUA47_RS13440 (MUA47_13440)	-	2710175..2710375 (-)	201	WP_262634688.1	hypothetical protein	-
MUA47_RS13445 (MUA47_13445)	-	2710573..2711997 (+)	1425	WP_000953759.1	alkaline phosphatase	-
MUA47_RS14160	-	2712057..2712158 (-)	102	WP_000731972.1	SE2200 family small protein	-
MUA47_RS13455 (MUA47_13455)	-	2712280..2712735 (-)	456	WP_000106185.1	MarR family winged helix-turn-helix transcriptional regulator	-
MUA47_RS13460 (MUA47_13460)	-	2712980..2713741 (-)	762	WP_000323448.1	alpha/beta hydrolase	-

Sequence

Protein

• Length: 295 a.a.
• Molecular weight: 34045.32 Da
• Isoelectric Point: 5.8962

>NTDB_id=672313 MUA47_RS13430 WP_000143420.1 2708586..2709473(-) (braS) [Staphylococcus aureus strain IVB6195]
MTFLKSITQEIAIVIVIFALFGLMFYLYHLPLEAYLLALGVILLLLLIFIGIKYLSFVKTISQQQQIENLENALYQLKNE
QIEYKNDVESYFLTWVHQMKTPITAAQLLLERDEPNVVNRVRQEVIQIDNYTSLALSYLKLLNETSDISVTKISINNIIR
PIIMKYSIQFIDQKTKIHYEPCHHEVLTDVRWTSLMIEQLINNALKYARGKDIWIEFDEQSNQLYVKDNGIGISEADLPK
IFDKGYSGYNGQRQSNSSGIGLFIVKQISTHTNHPVSVVSKQNEGTTFTIQFPDE

Nucleotide

• Length: 888 bp

>NTDB_id=672313 MUA47_RS13430 WP_000143420.1 2708586..2709473(-) (braS) [Staphylococcus aureus strain IVB6195]
ATGACCTTTCTTAAAAGTATTACTCAGGAAATAGCAATAGTCATAGTTATTTTTGCTTTATTTGGCTTAATGTTTTACCT
GTATCATTTGCCATTAGAAGCATATTTACTAGCACTTGGCGTTATTTTATTATTATTACTCATATTTATAGGTATTAAAT
ATTTAAGTTTTGTAAAAACTATAAGCCAACAACAACAAATTGAAAACTTAGAAAATGCGTTGTATCAGCTTAAAAATGAA
CAAATTGAATATAAAAATGATGTAGAGAGCTACTTTTTAACATGGGTACATCAAATGAAAACACCCATTACTGCAGCACA
ACTGTTACTTGAAAGAGATGAGCCTAATGTTGTGAATCGTGTTCGTCAAGAGGTTATTCAAATTGATAACTATACAAGTT
TAGCACTTAGTTATTTAAAGTTATTAAATGAAACTTCTGATATTTCTGTCACTAAAATTTCGATTAACAATATCATTCGC
CCAATTATTATGAAATATTCAATACAGTTTATTGATCAAAAAACAAAAATCCATTATGAACCTTGTCATCACGAAGTATT
AACTGACGTTAGATGGACCTCTTTAATGATAGAACAATTAATAAATAATGCACTTAAGTATGCGAGAGGTAAAGATATAT
GGATTGAATTTGATGAGCAATCCAATCAATTATACGTAAAAGATAATGGTATCGGTATTAGTGAAGCGGACTTGCCTAAA
ATATTTGATAAGGGCTATTCAGGTTATAATGGCCAGCGGCAAAGTAACTCAAGTGGGATTGGTTTATTTATCGTAAAACA
AATTTCAACTCACACAAACCATCCTGTTTCAGTCGTATCTAAACAAAATGAGGGTACAACATTTACGATTCAATTTCCAG
ATGAATAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (191-294)

3D structure

• AlphaFold DB: A0A2S6DP21

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
braS	Staphylococcus aureus N315	99.322	100	0.993