Detailed information    

insolico Bioinformatically predicted

Overview

Name   agrA   Type   Regulator
Locus tag   MUA47_RS10340 Genome accession   NZ_CP094773
Coordinates   2094007..2094723 (+) Length   238 a.a.
NCBI ID   WP_000688492.1    Uniprot ID   A0A7U7IEW1
Organism   Staphylococcus aureus strain IVB6195     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 2089007..2099723
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  MUA47_RS10310 (MUA47_10310) - 2089222..2089848 (+) 627 WP_000522378.1 nitroreductase family protein -
  MUA47_RS10315 (MUA47_10315) - 2090209..2090994 (+) 786 WP_262634657.1 carbon-nitrogen family hydrolase -
  MUA47_RS14150 (MUA47_10320) hld 2091594..2091674 (-) 81 WP_000046022.1 delta-hemolysin -
  MUA47_RS10325 (MUA47_10325) - 2091964..2092527 (+) 564 WP_001105710.1 accessory gene regulator AgrB -
  MUA47_RS10330 (MUA47_10330) agrD 2092531..2092671 (+) 141 WP_000735197.1 cyclic lactone autoinducer peptide AgrD -
  MUA47_RS10335 (MUA47_10335) agrC 2092696..2093988 (+) 1293 WP_000387816.1 quorum-sensing sensor histidine kinase AgrC -
  MUA47_RS10340 (MUA47_10340) agrA 2094007..2094723 (+) 717 WP_000688492.1 quorum-sensing response regulator AgrA Regulator
  MUA47_RS10345 (MUA47_10345) - 2094795..2094902 (+) 108 WP_001803734.1 hypothetical protein -
  MUA47_RS10350 (MUA47_10350) - 2095086..2096048 (-) 963 WP_001253304.1 carbohydrate kinase family protein -
  MUA47_RS10355 (MUA47_10355) - 2096045..2097529 (-) 1485 WP_000141424.1 sucrose-6-phosphate hydrolase -
  MUA47_RS10360 (MUA47_10360) - 2097678..2098628 (-) 951 WP_000790321.1 LacI family DNA-binding transcriptional regulator -

Sequence

Protein


Download         Length: 238 a.a.        Molecular weight: 27905.90 Da        Isoelectric Point: 6.0927

>NTDB_id=672309 MUA47_RS10340 WP_000688492.1 2094007..2094723(+) (agrA) [Staphylococcus aureus strain IVB6195]
MKIFICEDDPKQRENMVTIIKNYIMIEEKPMEIALATDNPYEVLEQAKNMNDIGCYFLDIQLSTDINGIKLGSEIRKHDP
VGNIIFVTSHSELTYLTFVYKVAAMDFIFKDDPAELRTRIIDCLETAHTRLQLLSKDNSVETIELKRGSNSVYVQYDDIM
FFESSTKSHRLIAHLDNRQIEFYGNLKELSQLDDRFFRCHNSFVVNRHNIESIDSKERIVYFKNKEHCYASVRNVKKI

Nucleotide


Download         Length: 717 bp        

>NTDB_id=672309 MUA47_RS10340 WP_000688492.1 2094007..2094723(+) (agrA) [Staphylococcus aureus strain IVB6195]
ATGAAAATTTTCATTTGCGAAGACGATCCAAAACAAAGAGAAAACATGGTTACCATTATTAAAAATTATATAATGATAGA
AGAAAAGCCTATGGAAATTGCCCTCGCAACTGATAATCCTTATGAGGTGCTTGAGCAAGCTAAAAATATGAATGACATAG
GCTGTTACTTTTTAGATATTCAACTTTCAACTGATATTAATGGTATCAAATTAGGCAGTGAAATTCGTAAGCATGATCCA
GTTGGTAACATTATATTTGTTACGAGTCACAGTGAACTTACCTATTTAACGTTTGTCTACAAAGTTGCAGCGATGGACTT
TATTTTTAAAGATGATCCAGCTGAATTAAGAACTCGAATTATAGACTGTTTAGAAACTGCACATACACGCTTACAATTGT
TGTCTAAAGATAATAGCGTTGAAACGATTGAATTAAAACGTGGCAGTAATTCAGTGTATGTTCAATATGATGATATTATG
TTTTTTGAATCATCAACAAAATCTCACAGACTCATTGCCCATTTAGATAACCGTCAAATTGAATTTTATGGTAATTTAAA
AGAACTGAGTCAATTAGATGATCGTTTCTTTAGATGTCATAATAGCTTTGTCGTCAATCGCCATAATATTGAATCTATAG
ATTCGAAAGAGCGAATTGTCTATTTTAAAAATAAAGAACACTGCTATGCATCGGTGAGAAACGTTAAAAAAATATAA

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(3-120)

LytTr DNA-binding domain (LytTR)

(151-237)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A7U7IEW1

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  agrA Staphylococcus aureus N315

100

100

1