Detailed information NTG0672231

Bioinformatically predicted

Overview

• Name: braS
• Type: Regulator
• Locus tag: MUA35_RS13515
• Genome accession: NZ_CP094770
• Coordinates: 2696352..2697239 (-)
• Length: 295 a.a.
• NCBI ID: WP_000143420.1
• Uniprot ID: A0A2S6DP21
• Organism: Staphylococcus aureus strain IVB6201
• Function: promote expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 2691352..2702239

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
MUA35_RS13490 (MUA35_13450)	-	2691366..2691458 (+)	93	WP_010956583.1	hypothetical protein	-
MUA35_RS13495 (MUA35_13455)	-	2691566..2692063 (-)	498	WP_262538011.1	glutathione peroxidase	-
MUA35_RS13500 (MUA35_13460)	-	2692073..2692333 (-)	261	WP_014532715.1	hypothetical protein	-
MUA35_RS13505 (MUA35_13465)	-	2693491..2695491 (-)	2001	WP_262607737.1	ABC transporter permease	-
MUA35_RS13510 (MUA35_13470)	-	2695488..2696244 (-)	757	Protein_2621	ABC transporter ATP-binding protein	-
MUA35_RS13515 (MUA35_13475)	braS	2696352..2697239 (-)	888	WP_000143420.1	nisin susceptibility-associated two-component system sensor histidine kinase NsaS	Regulator
MUA35_RS13520 (MUA35_13480)	braR	2697250..2697915 (-)	666	WP_000697877.1	nisin susceptibility-associated two-component system response regulator NsaR	Regulator
MUA35_RS13525 (MUA35_13485)	-	2697941..2698141 (-)	201	WP_262607738.1	hypothetical protein	-
MUA35_RS13530 (MUA35_13490)	-	2698339..2699763 (+)	1425	WP_000948998.1	alkaline phosphatase	-
MUA35_RS14030	-	2699823..2699924 (-)	102	WP_000731972.1	SE2200 family small protein	-
MUA35_RS13540 (MUA35_13500)	-	2700046..2700501 (-)	456	WP_000106185.1	MarR family winged helix-turn-helix transcriptional regulator	-
MUA35_RS13545 (MUA35_13505)	-	2700746..2701507 (-)	762	WP_000323448.1	alpha/beta hydrolase family protein	-

Sequence

Protein

• Length: 295 a.a.
• Molecular weight: 34045.32 Da
• Isoelectric Point: 5.8962

>NTDB_id=672231 MUA35_RS13515 WP_000143420.1 2696352..2697239(-) (braS) [Staphylococcus aureus strain IVB6201]
MTFLKSITQEIAIVIVIFALFGLMFYLYHLPLEAYLLALGVILLLLLIFIGIKYLSFVKTISQQQQIENLENALYQLKNE
QIEYKNDVESYFLTWVHQMKTPITAAQLLLERDEPNVVNRVRQEVIQIDNYTSLALSYLKLLNETSDISVTKISINNIIR
PIIMKYSIQFIDQKTKIHYEPCHHEVLTDVRWTSLMIEQLINNALKYARGKDIWIEFDEQSNQLYVKDNGIGISEADLPK
IFDKGYSGYNGQRQSNSSGIGLFIVKQISTHTNHPVSVVSKQNEGTTFTIQFPDE

Nucleotide

• Length: 888 bp

>NTDB_id=672231 MUA35_RS13515 WP_000143420.1 2696352..2697239(-) (braS) [Staphylococcus aureus strain IVB6201]
ATGACCTTTCTTAAAAGTATTACTCAGGAAATAGCAATAGTCATAGTTATTTTTGCTTTATTTGGCTTAATGTTTTACCT
GTATCATTTGCCATTAGAAGCATATTTACTAGCACTTGGCGTTATTTTATTATTATTACTCATATTTATAGGTATTAAAT
ATTTAAGTTTTGTAAAAACTATAAGCCAACAACAACAAATTGAAAACTTAGAAAATGCGTTGTATCAGCTTAAAAATGAA
CAAATTGAATATAAAAATGATGTAGAGAGCTACTTTTTAACATGGGTACATCAAATGAAAACACCCATTACTGCAGCACA
ACTGTTACTTGAAAGAGATGAGCCTAATGTTGTGAATCGTGTTCGTCAAGAGGTTATTCAAATTGATAACTATACAAGTT
TAGCACTTAGTTATTTAAAGTTATTAAATGAAACTTCTGATATTTCTGTCACTAAAATTTCGATTAACAATATCATTCGC
CCAATTATTATGAAATATTCAATACAGTTTATTGATCAAAAAACAAAAATCCATTATGAACCTTGTCATCACGAAGTATT
AACTGACGTTAGATGGACCTCTTTAATGATAGAACAATTAATAAATAATGCACTTAAGTATGCGAGAGGTAAAGATATAT
GGATTGAATTTGATGAGCAATCCAATCAATTATACGTAAAAGATAATGGTATCGGTATTAGTGAAGCGGACTTGCCTAAA
ATATTTGATAAGGGCTATTCAGGTTATAATGGCCAGCGGCAAAGTAACTCAAGTGGGATTGGTTTATTTATCGTAAAACA
AATTTCAACTCACACAAACCATCCTGTTTCAGTCGTATCTAAACAAAATGAGGGTACAACATTTACGATTCAATTTCCAG
ATGAATAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (191-294)

3D structure

• AlphaFold DB: A0A2S6DP21

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
braS	Staphylococcus aureus N315	99.322	100	0.993