Detailed information    

insolico Bioinformatically predicted

Overview

Name   agrA   Type   Regulator
Locus tag   MUA35_RS10480 Genome accession   NZ_CP094770
Coordinates   2088804..2089520 (+) Length   238 a.a.
NCBI ID   WP_218631715.1    Uniprot ID   -
Organism   Staphylococcus aureus strain IVB6201     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 2083804..2094520
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  MUA35_RS10450 (MUA35_10415) - 2084021..2084647 (+) 627 WP_262607628.1 nitroreductase family protein -
  MUA35_RS10455 (MUA35_10420) - 2085008..2085793 (+) 786 WP_262607629.1 carbon-nitrogen family hydrolase -
  MUA35_RS10460 (MUA35_10425) hld 2086392..2086472 (-) 81 WP_000046022.1 delta-hemolysin -
  MUA35_RS10465 (MUA35_10430) - 2086763..2087326 (+) 564 WP_001105699.1 accessory gene regulator AgrB -
  MUA35_RS10470 (MUA35_10435) agrD 2087329..2087472 (+) 144 WP_001094921.1 cyclic lactone autoinducer peptide AgrD -
  MUA35_RS10475 (MUA35_10440) agrC 2087502..2088785 (+) 1284 WP_262607630.1 quorum-sensing sensor histidine kinase AgrC -
  MUA35_RS10480 (MUA35_10445) agrA 2088804..2089520 (+) 717 WP_218631715.1 quorum-sensing response regulator AgrA Regulator
  MUA35_RS10485 (MUA35_10450) - 2089592..2089699 (+) 108 WP_042900011.1 hypothetical protein -
  MUA35_RS10490 (MUA35_10455) - 2089889..2090848 (-) 960 WP_262607631.1 carbohydrate kinase -
  MUA35_RS10495 (MUA35_10460) - 2090845..2092329 (-) 1485 WP_262538414.1 sucrose-6-phosphate hydrolase -
  MUA35_RS10500 (MUA35_10465) - 2092479..2093429 (-) 951 WP_000790321.1 LacI family DNA-binding transcriptional regulator -

Sequence

Protein


Download         Length: 238 a.a.        Molecular weight: 27845.86 Da        Isoelectric Point: 6.0918

>NTDB_id=672227 MUA35_RS10480 WP_218631715.1 2088804..2089520(+) (agrA) [Staphylococcus aureus strain IVB6201]
MKIFICEDDPKQRENMVTIIKNYIMIEEKPMEIALATDNPYEVLEQAKNMNDIGCYFLDIQLSTDINGIKLGSEIRKHDP
VGNIIFVTSHSELTYLTFVYKVAAMDFIFKDDPAELRTRIIDCLETAHTRLQLLSKDNSVETIELKRGSNSVCVQYDDIM
FFESSTKSHRLIAHLDNRQIEFYGNLKELSQLDDRFFRCHNSFVVNRHNIESIDSKERIVYFKNKEHCYASVRNVKKI

Nucleotide


Download         Length: 717 bp        

>NTDB_id=672227 MUA35_RS10480 WP_218631715.1 2088804..2089520(+) (agrA) [Staphylococcus aureus strain IVB6201]
ATGAAAATTTTCATTTGCGAAGACGATCCAAAACAAAGAGAAAACATGGTTACCATTATTAAAAATTATATAATGATAGA
AGAAAAGCCTATGGAAATTGCCCTCGCAACTGATAATCCTTATGAGGTGCTTGAGCAAGCTAAAAATATGAATGACATAG
GCTGTTACTTTTTAGATATTCAACTTTCAACTGATATTAATGGTATCAAATTAGGCAGTGAAATTCGTAAGCATGATCCA
GTTGGTAACATTATATTTGTTACGAGTCACAGTGAACTTACCTATTTAACGTTTGTCTACAAAGTTGCAGCGATGGATTT
TATTTTTAAAGATGATCCAGCTGAATTAAGAACTCGAATTATAGACTGTTTAGAAACTGCACATACACGCTTACAATTGT
TGTCTAAAGATAATAGCGTTGAAACGATTGAATTAAAACGTGGCAGTAATTCAGTGTGTGTTCAATATGATGATATTATG
TTTTTTGAATCATCAACAAAATCTCACAGACTCATTGCCCATTTAGATAACCGTCAAATTGAATTTTATGGTAATTTAAA
AGAACTGAGTCAATTAGATGATCGTTTCTTTAGATGTCATAATAGCTTTGTCGTCAATCGCCATAATATTGAATCTATAG
ATTCGAAAGAGCGAATTGTCTATTTTAAAAATAAAGAACACTGCTATGCATCGGTGAGAAACGTTAAAAAAATATAA

Domains

Predicted by InterproScan.

LytTr DNA-binding domain (LytTR)

(152-237)

Response regulator receiver domain (Response_reg)

(3-120)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  agrA Staphylococcus aureus N315

99.58

100

0.996