Detailed information NTG0672226

Bioinformatically predicted

Overview

• Name: vraS
• Type: Regulator
• Locus tag: MUA35_RS09970
• Genome accession: NZ_CP094770
• Coordinates: 1992992..1994035 (-)
• Length: 347 a.a.
• NCBI ID: WP_262607610.1
• Uniprot ID: -
• Organism: Staphylococcus aureus strain IVB6201
• Function: repress expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 1987992..1999035

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
MUA35_RS09940 (MUA35_09905)	-	1988410..1989666 (-)	1257	WP_001793428.1	aminopeptidase	-
MUA35_RS09945 (MUA35_09910)	-	1989669..1989869 (-)	201	WP_000180462.1	DUF1128 family protein	-
MUA35_RS09950 (MUA35_09915)	-	1990016..1990480 (+)	465	WP_000228666.1	low molecular weight protein-tyrosine-phosphatase	-
MUA35_RS09955 (MUA35_09920)	-	1990487..1990762 (+)	276	WP_000428172.1	YtxH domain-containing protein	-
MUA35_RS09960 (MUA35_09925)	-	1991040..1992257 (+)	1218	WP_000037088.1	YihY/virulence factor BrkB family protein	-
MUA35_RS09965 (MUA35_09930)	vraR	1992373..1993002 (-)	630	WP_000153530.1	two-component system response regulator VraR	Regulator
MUA35_RS09970 (MUA35_09935)	vraS	1992992..1994035 (-)	1044	WP_262607610.1	sensor histidine kinase	Regulator
MUA35_RS09975 (MUA35_09940)	liaF	1994032..1994733 (-)	702	WP_262607611.1	cell wall-active antibiotics response protein LiaF	-
MUA35_RS09980 (MUA35_09945)	-	1994748..1995134 (-)	387	WP_001110179.1	hypothetical protein	-
MUA35_RS09985 (MUA35_09950)	map	1995351..1996109 (-)	759	WP_000636142.1	type I methionyl aminopeptidase	-
MUA35_RS09990 (MUA35_09955)	-	1996638..1997624 (+)	987	WP_000999713.1	aromatic acid exporter family protein	-
MUA35_RS09995 (MUA35_09960)	-	1997998..1998411 (-)	414	WP_262608065.1	hypothetical protein	-
MUA35_RS10000 (MUA35_09965)	-	1998441..1998553 (-)	113	Protein_1931	hypothetical protein	-

Sequence

Protein

• Length: 347 a.a.
• Molecular weight: 40071.55 Da
• Isoelectric Point: 6.0577

>NTDB_id=672226 MUA35_RS09970 WP_262607610.1 1992992..1994035(-) (vraS) [Staphylococcus aureus strain IVB6201]
MNHYIRTIGSMLILVYSMLAAFLFIDKVFVNIIYFQGMFYTQIFGIPVFLFLNLIIILLCIIVGSVLAYKINQQNDWIKT
QIERSMEGETVGINDQNIEIYNETLDLYHTLVPLNQELHKLRLKTQNLTNENYNINDVKVKKIIEDERQRLARELHDSVS
QQLFAASMMLSAIKETKLEPPLDQQIPILEKMVQDSQLEMRALLLHLRPLGLKDKSLGEGIKDLVIDLQKKVPMKVVHEI
QDFKVPKGIEDHLFRITQEAISNTLRHSNGTKVTVELFNKDDYLLLRIQDNGKGFNVDEKLEQSYGLKNMRERALEIGAT
FHIVSLPDSGTRIEVKAPLNKEDSYDD

Nucleotide

• Length: 1044 bp

>NTDB_id=672226 MUA35_RS09970 WP_262607610.1 1992992..1994035(-) (vraS) [Staphylococcus aureus strain IVB6201]
ATGAACCACTACATTAGAACAATTGGTTCAATGCTCATCTTAGTATATAGCATGCTAGCTGCATTTCTGTTCATCGATAA
AGTTTTTGTAAATATCATCTATTTTCAAGGTATGTTTTATACACAAATATTCGGAATACCAGTCTTTTTATTTTTAAATC
TCATCATCATATTATTGTGTATTATTGTTGGTTCGGTACTCGCTTACAAAATCAATCAGCAAAATGATTGGATTAAGACG
CAAATTGAGCGTTCAATGGAAGGCGAAACAGTTGGCATTAATGATCAAAATATAGAAATATATAATGAAACGTTAGATTT
ATACCATACACTCGTACCTTTAAATCAAGAATTGCATAAGTTGCGACTTAAAACTCAAAACTTAACCAATGAAAATTATA
ATATTAATGATGTGAAAGTTAAAAAGATTATTGAAGATGAACGTCAAAGACTAGCACGAGAACTTCACGATTCTGTTAGT
CAGCAACTTTTTGCGGCAAGTATGATGCTATCTGCTATCAAAGAAACGAAGTTAGAACCACCATTAGACCAACAAATTCC
GATTTTAGAGAAAATGGTTCAAGATTCGCAGTTAGAAATGCGTGCTTTGCTGTTACATTTAAGACCTCTTGGTTTAAAAG
ACAAATCTTTAGGTGAGGGTATTAAAGATTTAGTTATTGATTTACAAAAAAAAGTGCCAATGAAAGTTGTGCATGAAATA
CAAGATTTTAAAGTGCCTAAAGGTATTGAAGATCATTTGTTCAGAATTACACAGGAAGCAATTTCGAATACATTGCGTCA
TTCAAACGGTACAAAAGTGACAGTAGAATTGTTTAATAAAGACGATTATTTATTGTTGAGAATTCAAGACAATGGTAAAG
GTTTTAATGTTGATGAAAAATTAGAACAAAGTTATGGACTTAAAAATATGCGTGAAAGAGCTTTGGAAATTGGTGCAACG
TTCCATATTGTATCATTGCCAGATTCAGGTACACGTATCGAGGTGAAAGCACCTTTAAATAAGGAGGATTCGTATGACGA
TTAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (249-340)

• Histidine kinase (HisKA_3) (147-210)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vraS	Staphylococcus aureus N315	99.712	100	0.997