Detailed information NTG0067222

Bioinformatically predicted

Overview

• Name: cytR
• Type: Regulator
• Locus tag: H7R25_RS22015
• Genome accession: NZ_AP022261
• Coordinates: 4632152..4633177 (+)
• Length: 341 a.a.
• NCBI ID: WP_000644904.1
• Uniprot ID: P0ACN8
• Organism: Escherichia coli strain WP8-S18-ESBL-07
• Function: promote competence gene expression (predicted from homology) Competence regulation

Genomic Context

Location: 4627152..4638177

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
H7R25_RS21995 (WP8S18E07_42760)	metJ	4628337..4628654 (+)	318	WP_000852812.1	met regulon transcriptional regulator MetJ	-
H7R25_RS22000 (WP8S18E07_42770)	yiiX	4628714..4629322 (+)	609	WP_000702318.1	YiiX family permuted papain-like enzyme	-
H7R25_RS22005 (WP8S18E07_42780)	rpmE	4629383..4629595 (-)	213	WP_000710769.1	50S ribosomal protein L31	-
H7R25_RS22010 (WP8S18E07_42790)	priA	4629798..4631996 (+)	2199	WP_001545073.1	primosomal protein N'	Machinery gene
H7R25_RS22015 (WP8S18E07_42800)	cytR	4632152..4633177 (+)	1026	WP_000644904.1	DNA-binding transcriptional regulator CytR	Regulator
H7R25_RS22020 (WP8S18E07_42810)	ftsN	4633269..4634228 (+)	960	WP_000068834.1	cell division protein FtsN	-
H7R25_RS22025 (WP8S18E07_42820)	hslV	4634321..4634851 (+)	531	WP_000208242.1	ATP-dependent protease subunit HslV	-
H7R25_RS22030 (WP8S18E07_42830)	hslU	4634861..4636192 (+)	1332	WP_001293344.1	HslU--HslV peptidase ATPase subunit	-
H7R25_RS22035 (WP8S18E07_42840)	menA	4636259..4637185 (+)	927	WP_001545069.1	1,4-dihydroxy-2-naphthoate polyprenyltransferase	-
H7R25_RS22040 (WP8S18E07_42850)	rraA	4637278..4637763 (+)	486	WP_001545067.1	ribonuclease E activity regulator RraA	-

Sequence

Protein

• Length: 341 a.a.
• Molecular weight: 37819.78 Da
• Isoelectric Point: 6.3842

>NTDB_id=67222 H7R25_RS22015 WP_000644904.1 4632152..4633177(+) (cytR) [Escherichia coli strain WP8-S18-ESBL-07]
MKAKKQETAATMKDVALKAKVSTATVSRALMNPDKVSQATRNRVEKAAREVGYLPQPMGRNVKRNESRTILVIVPDICDP
FFSEIIRGIEVTAANHGYLVLIGDCAHQNQQEKTFIDLIITKQIDGMLLLGSRLPFDASIEEQRNLPPMVMANEFAPELE
LPTVHIDNLTAAFDAVNYLYEQGHKRIGCIAGPEEMPLCHYRLQGYVQALRRCGIMVDPQYIARGDFTFEAGSKAMQQLL
DLPQPPTAVFCHSDVMALGALSQAKRQGLKVPEDLSIIGFDNIDLTQFCDPPLTTIAQPRYEIGREAMLLLLDQMQGQHV
GSGSRLMDCELIIRGSTRALP

Nucleotide

• Length: 1026 bp

>NTDB_id=67222 H7R25_RS22015 WP_000644904.1 4632152..4633177(+) (cytR) [Escherichia coli strain WP8-S18-ESBL-07]
GTGAAAGCGAAGAAGCAGGAAACTGCCGCGACCATGAAAGACGTTGCCCTCAAGGCAAAAGTCTCTACAGCGACCGTCTC
CCGAGCATTAATGAATCCCGATAAAGTCTCCCAGGCCACCCGTAATCGGGTTGAAAAAGCGGCCCGGGAAGTGGGTTATT
TACCGCAGCCTATGGGGCGCAACGTCAAGCGTAATGAATCCCGCACTATTCTGGTGATTGTCCCGGATATCTGCGATCCC
TTCTTTAGCGAAATTATTCGCGGTATCGAAGTTACGGCGGCAAATCACGGATATCTGGTGCTGATTGGCGACTGTGCGCA
TCAAAATCAGCAGGAAAAAACCTTTATCGATTTGATCATCACCAAGCAAATTGATGGCATGTTGCTGCTGGGTTCAAGGC
TGCCGTTTGATGCCAGCATTGAGGAACAGCGTAATCTGCCGCCGATGGTGATGGCGAACGAATTTGCACCGGAACTGGAG
CTGCCTACAGTTCATATCGACAATCTGACCGCCGCATTTGATGCAGTAAATTATTTATATGAGCAAGGGCATAAACGGAT
TGGCTGTATAGCCGGTCCCGAAGAGATGCCGCTGTGTCACTACCGCCTGCAAGGCTATGTCCAGGCGCTGCGTCGCTGCG
GCATTATGGTTGATCCGCAATACATCGCCCGTGGCGACTTCACCTTCGAAGCTGGAAGCAAAGCAATGCAACAGCTGCTT
GATCTTCCACAACCGCCTACTGCTGTCTTCTGCCATAGTGATGTGATGGCGCTCGGCGCACTTTCGCAGGCAAAACGCCA
GGGGCTGAAAGTCCCGGAAGACCTTTCCATAATCGGTTTTGATAACATCGACCTGACGCAATTTTGTGATCCGCCGCTGA
CAACCATCGCGCAGCCGCGTTACGAAATCGGTCGGGAAGCTATGCTGTTATTGCTTGATCAAATGCAGGGGCAACACGTT
GGCAGTGGCTCTCGTTTAATGGACTGCGAACTTATCATCCGGGGATCAACACGCGCGTTACCTTAA

Domains

Predicted by InterProScan.

• Bacterial regulatory proteins, lacI family (LacI) (11-56)

• Periplasmic binding protein-like domain (Peripla_BP_3) (176-337)

3D structure

• AlphaFold DB: P0ACN8

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
cytR	Vibrio parahaemolyticus RIMD 2210633	64.179	98.24	0.63
cytR	Vibrio cholerae C6706	65.443	95.894	0.628