Detailed information NTG0672100

Bioinformatically predicted

Overview

• Name: braS
• Type: Regulator
• Locus tag: MUA83_RS13455
• Genome accession: NZ_CP094763
• Coordinates: 2705977..2706864 (-)
• Length: 295 a.a.
• NCBI ID: WP_000143420.1
• Uniprot ID: A0A2S6DP21
• Organism: Staphylococcus aureus strain IVB6221
• Function: promote expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 2700977..2711864

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
MUA83_RS13425 (MUA83_13420)	-	2700980..2701072 (+)	93	WP_010956583.1	hypothetical protein	-
MUA83_RS13430 (MUA83_13425)	-	2701180..2701677 (-)	498	WP_001065267.1	glutathione peroxidase	-
MUA83_RS13435 (MUA83_13430)	-	2701687..2701947 (-)	261	WP_014532715.1	hypothetical protein	-
MUA83_RS13440 (MUA83_13435)	-	2702329..2702442 (-)	114	WP_072357681.1	hypothetical protein	-
MUA83_RS13445 (MUA83_13440)	-	2703117..2705117 (-)	2001	WP_000776732.1	ABC transporter permease	-
MUA83_RS13450 (MUA83_13445)	-	2705114..2705869 (-)	756	WP_044122909.1	ABC transporter ATP-binding protein	-
MUA83_RS13455 (MUA83_13450)	braS	2705977..2706864 (-)	888	WP_000143420.1	nisin susceptibility-associated two-component system sensor histidine kinase NsaS	Regulator
MUA83_RS13460 (MUA83_13455)	braR	2706875..2707540 (-)	666	WP_000697877.1	nisin susceptibility-associated two-component system response regulator NsaR	Regulator
MUA83_RS13465 (MUA83_13460)	-	2707566..2707766 (-)	201	WP_000604727.1	hypothetical protein	-
MUA83_RS13470 (MUA83_13465)	-	2707964..2709387 (+)	1424	Protein_2615	alkaline phosphatase	-
MUA83_RS14080	-	2709447..2709548 (-)	102	WP_000731972.1	SE2200 family small protein	-
MUA83_RS13480 (MUA83_13475)	-	2709670..2710125 (-)	456	WP_000106185.1	MarR family winged helix-turn-helix transcriptional regulator	-
MUA83_RS13485 (MUA83_13480)	-	2710370..2711131 (-)	762	WP_000323443.1	alpha/beta hydrolase family protein	-

Sequence

Protein

• Length: 295 a.a.
• Molecular weight: 34045.32 Da
• Isoelectric Point: 5.8962

>NTDB_id=672100 MUA83_RS13455 WP_000143420.1 2705977..2706864(-) (braS) [Staphylococcus aureus strain IVB6221]
MTFLKSITQEIAIVIVIFALFGLMFYLYHLPLEAYLLALGVILLLLLIFIGIKYLSFVKTISQQQQIENLENALYQLKNE
QIEYKNDVESYFLTWVHQMKTPITAAQLLLERDEPNVVNRVRQEVIQIDNYTSLALSYLKLLNETSDISVTKISINNIIR
PIIMKYSIQFIDQKTKIHYEPCHHEVLTDVRWTSLMIEQLINNALKYARGKDIWIEFDEQSNQLYVKDNGIGISEADLPK
IFDKGYSGYNGQRQSNSSGIGLFIVKQISTHTNHPVSVVSKQNEGTTFTIQFPDE

Nucleotide

• Length: 888 bp

>NTDB_id=672100 MUA83_RS13455 WP_000143420.1 2705977..2706864(-) (braS) [Staphylococcus aureus strain IVB6221]
ATGACCTTTCTTAAAAGTATTACTCAGGAAATAGCAATAGTCATAGTTATTTTTGCTTTATTTGGCTTAATGTTTTACCT
GTATCATTTGCCATTAGAAGCATATTTACTAGCACTTGGCGTTATTTTATTATTATTACTCATATTTATAGGTATTAAAT
ATTTAAGTTTTGTAAAAACTATAAGCCAACAACAACAAATTGAAAACTTAGAAAATGCGTTGTATCAGCTTAAAAATGAA
CAAATTGAATATAAAAATGATGTAGAGAGCTACTTTTTAACATGGGTACATCAAATGAAAACACCCATTACTGCAGCACA
ACTGTTACTTGAAAGAGATGAGCCTAATGTTGTGAATCGTGTTCGTCAAGAGGTTATTCAAATTGATAACTATACAAGTT
TAGCACTTAGTTATTTAAAGTTATTAAATGAAACTTCTGATATTTCTGTCACTAAAATTTCGATTAACAATATCATTCGC
CCAATTATTATGAAATATTCAATACAGTTTATTGATCAAAAAACAAAAATCCATTATGAACCTTGTCATCACGAAGTATT
AACTGACGTTAGATGGACCTCTTTAATGATAGAACAATTAATAAATAATGCACTTAAGTATGCGAGAGGTAAAGATATAT
GGATTGAATTTGATGAGCAATCCAATCAATTATACGTAAAAGATAATGGTATCGGTATTAGTGAAGCGGACTTGCCTAAA
ATATTTGATAAGGGCTATTCAGGTTATAATGGCCAGCGGCAAAGTAACTCAAGTGGGATTGGTTTATTTATCGTAAAACA
AATTTCAACTCACACAAACCATCCTGTTTCAGTCGTATCTAAACAAAATGAGGGTACAACATTTACGATTCAATTTCCAG
ATGAATAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (191-294)

3D structure

• AlphaFold DB: A0A2S6DP21

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
braS	Staphylococcus aureus N315	99.322	100	0.993