Detailed information NTG0672061

Bioinformatically predicted

Overview

• Name: braS
• Type: Regulator
• Locus tag: MUA14_RS12865
• Genome accession: NZ_CP094760
• Coordinates: 2617313..2618200 (-)
• Length: 295 a.a.
• NCBI ID: WP_000143420.1
• Uniprot ID: A0A2S6DP21
• Organism: Staphylococcus aureus strain IVB6232
• Function: promote expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 2612313..2623200

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
MUA14_RS12835 (MUA14_12825)	-	2612316..2612408 (+)	93	WP_010956583.1	hypothetical protein	-
MUA14_RS12840 (MUA14_12830)	-	2612516..2613013 (-)	498	WP_001065267.1	glutathione peroxidase	-
MUA14_RS12845 (MUA14_12835)	-	2613023..2613283 (-)	261	WP_014532715.1	hypothetical protein	-
MUA14_RS12850 (MUA14_12840)	-	2613665..2613778 (-)	114	WP_072357681.1	hypothetical protein	-
MUA14_RS12855 (MUA14_12845)	-	2614453..2616453 (-)	2001	WP_000776732.1	ABC transporter permease	-
MUA14_RS12860 (MUA14_12850)	-	2616450..2617205 (-)	756	WP_044122909.1	ABC transporter ATP-binding protein	-
MUA14_RS12865 (MUA14_12855)	braS	2617313..2618200 (-)	888	WP_000143420.1	nisin susceptibility-associated two-component system sensor histidine kinase NsaS	Regulator
MUA14_RS12870 (MUA14_12860)	braR	2618211..2618876 (-)	666	WP_000697877.1	nisin susceptibility-associated two-component system response regulator NsaR	Regulator
MUA14_RS12875 (MUA14_12865)	-	2618902..2619102 (-)	201	WP_000604727.1	hypothetical protein	-
MUA14_RS12880 (MUA14_12870)	-	2619300..2620724 (+)	1425	WP_000948997.1	alkaline phosphatase	-
MUA14_RS13495	-	2620784..2620885 (-)	102	WP_000731972.1	SE2200 family small protein	-
MUA14_RS12890 (MUA14_12880)	-	2621007..2621462 (-)	456	WP_000106185.1	MarR family winged helix-turn-helix transcriptional regulator	-
MUA14_RS12895 (MUA14_12885)	-	2621722..2622468 (-)	747	WP_070044269.1	alpha/beta hydrolase family protein	-

Sequence

Protein

• Length: 295 a.a.
• Molecular weight: 34045.32 Da
• Isoelectric Point: 5.8962

>NTDB_id=672061 MUA14_RS12865 WP_000143420.1 2617313..2618200(-) (braS) [Staphylococcus aureus strain IVB6232]
MTFLKSITQEIAIVIVIFALFGLMFYLYHLPLEAYLLALGVILLLLLIFIGIKYLSFVKTISQQQQIENLENALYQLKNE
QIEYKNDVESYFLTWVHQMKTPITAAQLLLERDEPNVVNRVRQEVIQIDNYTSLALSYLKLLNETSDISVTKISINNIIR
PIIMKYSIQFIDQKTKIHYEPCHHEVLTDVRWTSLMIEQLINNALKYARGKDIWIEFDEQSNQLYVKDNGIGISEADLPK
IFDKGYSGYNGQRQSNSSGIGLFIVKQISTHTNHPVSVVSKQNEGTTFTIQFPDE

Nucleotide

• Length: 888 bp

>NTDB_id=672061 MUA14_RS12865 WP_000143420.1 2617313..2618200(-) (braS) [Staphylococcus aureus strain IVB6232]
ATGACCTTTCTTAAAAGTATTACTCAGGAAATAGCAATAGTCATAGTTATTTTTGCTTTATTTGGCTTAATGTTTTACCT
GTATCATTTGCCATTAGAAGCATATTTACTAGCACTTGGCGTTATTTTATTATTATTACTCATATTTATAGGTATTAAAT
ATTTAAGTTTTGTAAAAACTATAAGCCAACAACAACAAATTGAAAACTTAGAAAATGCGTTGTATCAGCTTAAAAATGAA
CAAATTGAATATAAAAATGATGTAGAGAGCTACTTTTTAACATGGGTACATCAAATGAAAACACCCATTACTGCAGCACA
ACTGTTACTTGAAAGAGATGAGCCTAATGTTGTGAATCGTGTTCGTCAAGAGGTTATTCAAATTGATAACTATACAAGTT
TAGCACTTAGTTATTTAAAGTTATTAAATGAAACTTCTGATATTTCTGTCACTAAAATTTCGATTAACAATATCATTCGC
CCAATTATTATGAAATATTCAATACAGTTTATTGATCAAAAAACAAAAATCCATTATGAACCTTGTCATCACGAAGTATT
AACTGACGTTAGATGGACCTCTTTAATGATAGAACAATTAATAAATAATGCACTTAAGTATGCGAGAGGTAAAGATATAT
GGATTGAATTTGATGAGCAATCCAATCAATTATACGTAAAAGATAATGGTATCGGTATTAGTGAAGCGGACTTGCCTAAA
ATATTTGATAAGGGCTATTCAGGTTATAATGGCCAGCGGCAAAGTAACTCAAGTGGGATTGGTTTATTTATCGTAAAACA
AATTTCAACTCACACAAACCATCCTGTTTCAGTCGTATCTAAACAAAATGAGGGTACAACATTTACGATTCAATTTCCAG
ATGAATAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (191-294)

3D structure

• AlphaFold DB: A0A2S6DP21

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
braS	Staphylococcus aureus N315	99.322	100	0.993