Detailed information NTG0672056

Bioinformatically predicted

Overview

• Name: vraS
• Type: Regulator
• Locus tag: MUA14_RS09390
• Genome accession: NZ_CP094760
• Coordinates: 1935048..1936091 (-)
• Length: 347 a.a.
• NCBI ID: WP_001017131.1
• Uniprot ID: A0A0D1IMN4
• Organism: Staphylococcus aureus strain IVB6232
• Function: repress expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 1930048..1941091

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
MUA14_RS09360 (MUA14_09350)	-	1930469..1931725 (-)	1257	WP_001793428.1	aminopeptidase	-
MUA14_RS09365 (MUA14_09355)	-	1931728..1931928 (-)	201	WP_000180460.1	DUF1128 family protein	-
MUA14_RS09370 (MUA14_09360)	-	1932075..1932539 (+)	465	WP_000228666.1	low molecular weight protein-tyrosine-phosphatase	-
MUA14_RS09375 (MUA14_09365)	-	1932546..1932821 (+)	276	WP_000428172.1	YtxH domain-containing protein	-
MUA14_RS09380 (MUA14_09370)	-	1933099..1934316 (+)	1218	WP_045158466.1	YihY/virulence factor BrkB family protein	-
MUA14_RS09385 (MUA14_09375)	vraR	1934429..1935058 (-)	630	WP_000153530.1	two-component system response regulator VraR	Regulator
MUA14_RS09390 (MUA14_09380)	vraS	1935048..1936091 (-)	1044	WP_001017131.1	sensor histidine kinase	Regulator
MUA14_RS09395 (MUA14_09385)	liaF	1936088..1936789 (-)	702	WP_000149068.1	cell wall-active antibiotics response protein LiaF	-
MUA14_RS09400 (MUA14_09390)	-	1936804..1937190 (-)	387	WP_001110179.1	hypothetical protein	-
MUA14_RS09405 (MUA14_09395)	map	1937407..1938165 (-)	759	WP_000636142.1	type I methionyl aminopeptidase	-
MUA14_RS09410 (MUA14_09400)	-	1938806..1939792 (+)	987	WP_000999713.1	aromatic acid exporter family protein	-
MUA14_RS09415 (MUA14_09405)	-	1939981..1940394 (-)	414	WP_252550078.1	hypothetical protein	-
MUA14_RS09420 (MUA14_09410)	-	1940423..1940535 (-)	113	Protein_1814	hypothetical protein	-

Sequence

Protein

• Length: 347 a.a.
• Molecular weight: 40044.52 Da
• Isoelectric Point: 6.0577

>NTDB_id=672056 MUA14_RS09390 WP_001017131.1 1935048..1936091(-) (vraS) [Staphylococcus aureus strain IVB6232]
MNHYIRTIGSMLILVYSMLAAFLFIDKVFVNIIYFQGMFYTQIFGIPVFLFLNLIIILLCIIVGSVLAYKINQQNDWIKT
QIERSMEGETVGINDQNIEIYSETLDLYHTLVPLNQELHKLRLKTQNLTNENYNINDVKVKKIIEDERQRLARELHDSVS
QQLFAASMMLSAIKETKLEPPLDQQIPILEKMVQDSQLEMRALLLHLRPLGLKDKSLGEGIKDLVIDLQKKVPMKVVHEI
QDFKVPKGIEDHLFRITQEAISNTLRHSNGTKVTVELFNKDDYLLLRIQDNGKGFNVDEKLEQSYGLKNMRERALEIGAT
FHIVSLPDSGTRIEVKAPLNKEDSYDD

Nucleotide

• Length: 1044 bp

>NTDB_id=672056 MUA14_RS09390 WP_001017131.1 1935048..1936091(-) (vraS) [Staphylococcus aureus strain IVB6232]
ATGAACCACTACATTAGAACAATTGGTTCAATGCTCATCTTAGTATATAGCATGCTAGCTGCATTTCTGTTCATCGATAA
AGTTTTTGTAAATATCATCTATTTTCAAGGTATGTTTTATACACAAATATTCGGAATACCAGTCTTTTTATTTTTAAATC
TCATCATCATATTATTGTGTATTATTGTTGGTTCGGTACTCGCTTACAAAATCAATCAGCAAAATGATTGGATTAAGACG
CAAATTGAGCGTTCAATGGAAGGCGAAACAGTTGGCATTAATGATCAAAATATAGAAATATATAGTGAAACGTTAGATTT
ATACCATACACTCGTACCTTTAAATCAAGAATTGCATAAGTTGCGACTTAAAACTCAAAACTTAACCAATGAAAATTATA
ATATTAATGATGTGAAAGTTAAAAAGATTATTGAAGATGAACGTCAAAGACTAGCACGAGAACTTCACGATTCTGTTAGT
CAGCAACTTTTTGCGGCAAGTATGATGCTATCTGCTATCAAAGAAACGAAGTTAGAACCACCATTAGACCAACAAATTCC
GATTTTAGAGAAAATGGTTCAAGATTCGCAGTTAGAAATGCGTGCTTTACTGTTACATTTAAGACCGCTTGGTTTAAAAG
ACAAATCTTTAGGTGAGGGTATTAAAGATTTAGTTATTGATTTGCAAAAAAAAGTGCCAATGAAAGTTGTGCATGAAATA
CAAGATTTTAAAGTGCCTAAAGGTATTGAAGATCATTTGTTCAGAATTACACAGGAAGCAATTTCGAATACATTGCGTCA
TTCAAACGGTACAAAAGTGACAGTAGAATTGTTTAATAAAGACGATTATTTATTGTTGAGAATTCAAGACAATGGTAAAG
GTTTTAATGTTGATGAAAAATTAGAACAAAGTTATGGACTTAAAAATATGCGTGAAAGAGCTTTGGAAATTGGTGCAACG
TTCCATATTGTATCATTGCCAGATTCAGGTACACGTATCGAGGTGAAAGCACCTTTAAATAAGGAGGATTCGTATGACGA
TTAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (249-340)

• Histidine kinase (HisKA_3) (147-210)

3D structure

• AlphaFold DB: A0A0D1IMN4

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vraS	Staphylococcus aureus N315	100	100	1